Navigation Links
Oncolytics Biotech(R) Inc. Announces Publication of Research on Synergistic Activity of Reovirus and Chemotherapy in NSCLC
Date:7/16/2009

CALGARY, July 16 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) ('Oncolytics') reported today that Dr. Shizuko Sei et al. published the results of their work examining reovirus and chemotherapy against human non-small cell lung cancer (NSCLC). The paper, entitled "Synergistic Antitumor Activity of Oncolytic Reovirus and Chemotherapeutic Agents in Non-Small Cell Lung Cancer Cells" appears online in the July 14, 2009 issue of Molecular Cancer.

"This important study demonstrates that reovirus works synergistically in combination with chemotherapy, and in some instances can overcome significant multiple drug resistance in certain cell lines," said Dr. Brad Thompson, President and CEO of Oncolytics. "We are currently using drug combinations against NSCLC and head and neck cancers in two separate U.S. Phase II studies."

The investigators examined in vitro combination effects of reovirus alone and in combination with cisplatin, gemcitabine or vinblastine. When reovirus was used alone, it demonstrated significant cytolytic activity in 7 of 9 NSCLC cell lines examined. The combinations demonstrated strong synergistic effects on cell killing. The combination of reovirus and paclitaxel was invariably synergistic in all cell lines tested, regardless of their level of sensitivity to either agent.

The investigators concluded that the oncolytic activity of reovirus can be potentiated by taxanes and other chemotherapeutic agents, and that the reovirus-taxane combination most effectively achieves synergy through accelerated apoptosis triggered by prolonged mitotic arrest.

About Oncolytics Biotech Inc.

Oncolytics is a Calgary-based biotechnology company focused on the development of oncolytic viruses as potential cancer therapeutics. Oncolytics' clinical program includes a variety of Phase I/II and
'/>"/>

SOURCE Oncolytics Biotech Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Oncolytics Biotech Inc. Announces Start of Patient Enrolment in Translational Clinical Trial Investigating REOLYSIN(R) in Patients with Metastatic Colorectal Cancer
2. Cancer Therapy & Research Center at The University of Texas Health Science Center and Oncolytics Biotech(R) Inc. Announce Multi-Trial Clinical Research Collaboration
3. Oncolytics Biotech(R) Inc. Announces Start of Enrolment in U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
7. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
8. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
9. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
10. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
11. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... DIEGO , July 14, 2014  Diomics, ... material, today announced that the United States Patent ... held by Diomics covering novel biologic sample collection ... their use in forensics and diagnostics. ... materials is by swabbing. Recovery of DNA from ...
(Date:7/14/2014)... ANAHEIM, Calif. , July 14, 2014  Mallinckrodt plc ... QCOR ) today announced that the registration statement ... Commission ("SEC") by Mallinckrodt plc on May 16, 2014 and ... statement of Mallinckrodt and Questcor that also constitutes a prospectus ... registration statement on Form S-4 is available on the SEC,s ...
(Date:7/14/2014)... Francisco, Calif. , July 14, 2014 ... today announces a technology partnership with global ... develop its technology for quick-to-market products. ... approach and DNA2.0,s machine learning optimization technologies, ... speeding up the process of engineering proteins ...
Breaking Medicine Technology:Diomics Announces Issuance Of U.S. Patents For Novel Biologic Sample DNA Collection Materials For Use In Forensics And Diagnostics 2Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 2Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 3Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 4Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 5Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 6Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 7Pareto Biotechnologies Announces Technology Partnership With DNA2.0, Inc. 2Pareto Biotechnologies Announces Technology Partnership With DNA2.0, Inc. 3
... WASHINGTON, June 20, 2007 /PRNewswire-USNewswire/ -- Speaker,Nancy Pelosi ... Bush's veto of the stem cell bill: , ... of the American,people, of leading medical researchers, and ... veto says 'no' to the hopes of,million of ...
... Research and,Markets (http://www.researchandmarkets.com/reports/c60415) has,announced the addition of ... advancements in molecular research and continued untiring,efforts ... more precisely,applicable Pharmaceuticals as well as agro ... advent of Chiral technologies and their,applications. , ...
Cached Medicine Technology:New Report 'Looking at Chiral Technologies' Analyzes the Global,Market Growth Forecasts Driven By Two Very Important Components as,Single Isomer Drugs and Single Enantiomer Pharmaceuticals 2
(Date:7/14/2014)... Germany (PRWEB) July 14, 2014 EurekaMag.com ... Hepatitis C which is a contagious liver disease ... a few weeks to a serious, lifelong illness that ... the United States have chronic Hepatitis C virus infection ... While the site's research category covers all studies ...
(Date:7/14/2014)... 14, 2014 According to ... review recently updated by Vkool.com, this is ... wide range of simple and easy tips ... including:,     Increasing omega-3 fatty ... products ,     Increasing fiber , ...
(Date:7/14/2014)... 14, 2014 Carepoint has been ... caregiving by combining an intuitive interface for recording, ... robust service tracking and reporting features. , Hall ... has teamed up with Rebecca de Witte to ... healthcare organizations. , Carepoint provides seamless, ...
(Date:7/14/2014)... 14, 2014 Vaginal Mesh lawsuit ... seven different pelvic mesh manufacturers in the U.S. District ... Schulte LLC. The federal complaints are pending against pelvic ... American Medical Systems (MDL No. 2325), and C.R. Bard, ... are 58,262 Vaginal Mesh lawsuit claims pending, according to ...
(Date:7/14/2014)... DC (PRWEB) July 14, 2014 ... exchanges, carriers emphasized lower-cost narrow-network products, accountable care ... generally chose coverage based on price, rather than ... enrollees from seeking care from out-of-network providers. ... ACOs, Narrow Networks and Exchange Products,” the ...
Breaking Medicine News(10 mins):Health News:EurekaMag.com Publishes 64,900 New Studies on Hepatitis C 2Health News:Endometriosis Bible and Violet Protocol Book Review Exposes Zoe Brown's Endometriosis Treatment Guide – Vkool.com 2Health News:Endometriosis Bible and Violet Protocol Book Review Exposes Zoe Brown's Endometriosis Treatment Guide – Vkool.com 3Health News:Home Health Care Professional and Marketing Firm Team Up to Create New Homecare Communication App 2Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 2Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 3Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 4Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 5Health News:Milliman, FAIR Health Executives to Discuss Data-Based Rate Setting for Out-of-Network Providers in Atlantic Information Services Webinar 2
... ... don,t need the pretty bottles or sweet aroma of fragrant lotions and cleansers-men ... tailored specifically to a man,s needs without added synthetic ingredients that may be ... uses the purity of nature to enhance the skin,s surface and makes a ...
... ... Drive in Beverly Hills to Main Street in small towns across America. The medical community ... growing epidemic. , ... PA (PRWEB) June 1, 2010 -- Nearly 7 million Americans are abusing prescription drugs – ...
... ... Harmful Bacteria, Including MRSA. Jan-Pro, Global Leader in Commercial Cleaning, Once Again Leads the ... Offer Powerful New Solution in the control of infectious microorganisms - EnviroShield Disinfectant Technology ... (PRWEB) June ...
... ... of a novel combination of two FDA Approved topical medications. This triple blind controlled ... ... Oscar Klein M.D. today announced the results of a triple blind hair loss research study ...
... ... a brand new buy back plan. , ... (PRWEB) – CosmeticLaserWorld.com ( www.cosmeticlaserworld.com ), a market leader in ... should purchase equipment from the reseller. Under an Investment Protection Plan, the company will ...
... - Shionogi Pharma, Inc., a U.S.-based group company of ... results of two pivotal studies of the investigational new ... for the treatment of primary premature ejaculation (PE). These ... (AUA) Annual Meeting in San Francisco. Evaluating a ...
Cached Medicine News:Health News:Garden of Eve Launches a Father's Day Tribute for Men Who Want to Look Well-groomed with Little Fuss 2Health News:Garden of Eve Launches a Father's Day Tribute for Men Who Want to Look Well-groomed with Little Fuss 3Health News:Garden of Eve Launches a Father's Day Tribute for Men Who Want to Look Well-groomed with Little Fuss 4Health News:Medical Community Responds to Prescription Drug Abuse 2Health News:Medical Community Responds to Prescription Drug Abuse 3Health News:JAN-PRO Launches Exclusive “EnviroShield™” Disinfecting System - Kills Harmful Bacteria, Including MRSA 2Health News:JAN-PRO Launches Exclusive “EnviroShield™” Disinfecting System - Kills Harmful Bacteria, Including MRSA 3Health News:Hair Loss Research Study Reveals Important Breakthrough in the Treatment of Male Pattern Baldness 2Health News:Hair Loss Research Study Reveals Important Breakthrough in the Treatment of Male Pattern Baldness 3Health News:CosmeticLaserWorld.com Gives Buyers Peace of Mind Through Industry-Leading Investment Protection Plan 2Health News:Pivotal data for the investigational treatment PSD502 for primary premature ejaculation 2Health News:Pivotal data for the investigational treatment PSD502 for primary premature ejaculation 3
High resolution, multi-frequency, HST version of the UST-987-7.5. Provides even greater image detail, better resolution, and penetration....
... Penetration Steered Linear Peripheral Vascular transducer, with ... MHz. It is our newest vascular ... 4 different settings to optimize imaging of ... color and Doppler sensitivity of this transducer ...
... Super High Density, multi-frequency, linear ... "twist on the UST-5536, this ... it sweeps horizontally as well ... axis so that target lesions ...
... The UST-MC11-8731 is a perfect alternative ... are used to seeing more of a ... of the transducer in the hand., This ... shaped convex intraoperative transducer. The UST-MC11-8731 nestles ...
Medicine Products: