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OncoGenex Announces Multiple 'Trials in Progress' Presentations at the 2013 ASCO Annual Meeting
Date:5/22/2013

BOTHELL, Wash. and VANCOUVER, British Columbia, May 22, 2013 /PRNewswire/ -- OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI), a leader in the development of novel therapeutics to target mechanisms of treatment resistance in cancer, today announced that four trials of its investigational compounds, custirsen and OGX-427, will be presented as "Trials in Progress" posters at the 49th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, IL from May 31 – June 4.

Despite the availability of drugs that improve survival in patients with cancer, treatment failure attributed to resistance continues to be a major problem in medical oncology.1,2,3,4  Across multiple tumor types, the majority of patients with cancer are likely to face treatment resistance at some point.4,5,6

"At this year's ASCO we're highlighting the breadth and depth of our clinical development programs, which evaluate innovative therapies that target important mechanisms of cancer treatment resistance in a variety of cancers," said Scott Cormack , President and Chief Executive Officer, OncoGenex Pharmaceuticals, Inc. "With three Phase 3 trials for custirsen ongoing and multiple Phase 2 trials for OGX-427 underway, our development programs have never been stronger."

At ASCO, details will be presented on trial design and rationale for the Phase 3 AFFINITY trial. Additionally, three of five Phase 2 trials from the OGX-427 ORCA™ (Ongoing Studies Evaluating Treatment Resistance in CAncer) clinical trial program will be highlighted. 

  • Abstract #TPS5103: Design of the AFFINITY study: A randomized phase III study of a novel clusterin inhibitor, custirsen, plus cabazitax
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SOURCE OncoGenex Pharmaceuticals, Inc.
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1. OncoGenex Pharmaceuticals, Inc. Provides Clinical Development Program Overview and Reports Financial Results for First Quarter 2013
2. OncoGenex Pharmaceuticals, Inc. Provides Update on Clinical Development Program and Reports Financial Results for Fourth Quarter and Year End 2012
3. OncoGenex Announces Plans for the Initiation of the Borealis-2 Clinical Trial Evaluating OGX-427 in Combination with Second-Line Therapy for Bladder Cancer
4. OncoGenex Announces Initiation of the Phase 3 "AFFINITY" Trial for Patients with Advanced Prostate Cancer
5. OncoGenex Pharmaceuticals, Inc. Reports Second Quarter and First-Half 2012 Financial Results and Reviews Clinical Development Highlights for Custirsen and OGX-427
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