Navigation Links
Omeros and The Parkinson's Institute and Clinical Center Enter into a Collaboration Agreement to Evaluate Novel Target for the Treatment of Movement Disorders
Date:9/17/2008

SEATTLE and SUNNYVALE, Calif., Sept. 17 /PRNewswire/ -- Omeros Corporation and The Parkinson's Institute and Clinical Center today announced that they have entered into a collaboration to evaluate a novel target, proprietary to Omeros, for the treatment of movement disorders. The collaboration is based on Omeros' discovery and prior validation of a previously unknown link between this molecular target in the brain and movement disorders such as Parkinson's disease and Restless Legs Syndrome (RLS).

"We believe that the data from our earlier studies are the first to establish a link between our target and any movement disorder," stated Gregory A. Demopulos, M.D., Chairman and CEO of Omeros. "We are very pleased that The Parkinson's Institute and Dr. Langston, leaders in the field of Parkinson's disease, have chosen to work with Omeros to generate additional evidence for the potential clinical benefits of therapeutics directed to our proprietary target."

Under the collaboration, Omeros and The Parkinson's Institute will conduct laboratory studies of one or more compounds that block Omeros' proprietary target in a widely used and highly predictive model for the symptomatic treatment of Parkinson's disease. Omeros' earlier studies conducted at Emory University by Gary W. Miller, Ph.D. in a similar model showed that compounds blocking this target were as effective as levodopamine, or L-DOPA, the standard treatment for Parkinson's disease for nearly 40 years, at doses 50- to 100-times lower than those of L-DOPA. L-DOPA is also associated with side effects including dyskinesias, hallucinations, sleep disorders and cognitive impairment.

"Omeros' experimental data are the first that I have ever seen to show efficacy equivalent to that of L-DOPA," said Dr. J. William Langston, Scientific Director and Founder of The Parkinson's Institute and Clinical Center. "Based on the potential for lower dosing and the proposed mechanism of action for Omeros' tar
'/>"/>

SOURCE Omeros Corporation; The Parkinson?s Institute and ClinicalCenter
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Omeros Announces Initiation of Patient Enrollment in OMS201 Phase 1 Study
2. Omeros Announces Publication of Clinical Results for OMS103HP in Arthroscopy: The Journal of Arthroscopic and Related Surgery
3. Omeros Announces Patient Enrollment in Phase 1/Phase 2 Study of OMS302
4. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
5. Sports Legacy Institute Announces Findings of Forensic Examinations on Wrestler Chris Benoits Brain
6. Diabetes Research Institute Invention Promotes Growth of Stem Cells into Insulin-Producing Cells
7. Spine Institute of Louisiana Offers Cervical Spine Motion Preservation as an Alternative to Fusion Surgery
8. Trana Discovery and Southern Research Institute Announce the First RNA-RNA High Throughput Drug Screening Assay Platform for HIV Antivirals
9. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
10. Virogenomics, Inc. Awarded $2 Million National Institute of Standards and Technology (NIST) Advanced Technology Program Grant to Develop Integrated Diagnostic Biosensors
11. The Leukemia & Lymphoma Society and Cleveland Clinic Taussig Cancer Institute Announce Groundbreaking Partnership to Accelerate Drug Approvals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... N.J. , March 27, 2015  Johnson & Johnson ... Shareholders at 10 a.m. (Eastern Time) on Thursday, April 23, ... N.J. Investors and other interested parties ... visiting the Company,s website at www.jnj.com and clicking ... from the meeting will be made available a few hours ...
(Date:3/27/2015)... , March 27, 2015  WebMD Health ... source of health information, today announced an ... National Action Plan for Combating Antibiotic-Resistant ... emphasized the urgency and importance of addressing ... and global health.    The WebMD ...
(Date:3/26/2015)... "Whether it,s our family, our friends, all ... In a single sentence, Dr. Anthony Coyle , ... Centers for Therapeutic Innovation (CTI), sums up ... America,s biopharmaceutical companies. CTI,s unique model ... foundations and the National Institutes of Health (NIH) to ...
Breaking Medicine Technology:Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 2Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 3Collaboration for Cures: Teaming Up to Advance Science and Save Lives 2
... 12, 2007 - CombinatoRx,Incorporated (NASDAQ: CRXX), today ... efforts will be presented at the 98th,Annual ... Research,April 14-18, 2007 in Los Angeles, CA., ... Therapy", Heilbut, et.al. (Abstract #1410) will be ...
... Oncology Portfolio, SOUTH SAN FRANCISCO, Calif., April ... the presentation of four research projects aimed ... as,potential therapeutics for certain types of cancers ... presentations during,poster sessions from April 16th to ...
Cached Medicine Technology:CombinatoRx to Present Combination High Throughput Screening (cHTS),Data at Upcoming AACR Meeting 2CombinatoRx to Present Combination High Throughput Screening (cHTS),Data at Upcoming AACR Meeting 3Rigel to Present New Research Programs at AACR Meeting 2Rigel to Present New Research Programs at AACR Meeting 3Rigel to Present New Research Programs at AACR Meeting 4Rigel to Present New Research Programs at AACR Meeting 5
(Date:3/29/2015)... 2015 Adults who are comparing the ... on the web can now use the QuotesPros.com website ... can now be explored while researching the automated database ... the differences between what a term policy provides and ... for some men and women. Insurers typically provide base ...
(Date:3/29/2015)... 29, 2015 The federal court ... ) pending in the U.S. District Court, Northern ... Case Management Conference for April 21st at 1:30 ... address the progress of product liability claims filed ... attacks, strokes and other cardiovascular complications due to ...
(Date:3/29/2015)... (PRWEB) March 29, 2015 “Health is ... “and as we learn more about the cannabinoid system ... March Homeostasis: Publius’ Go Endo-Cannabinoid Update ~ ... or endo-healing, is celebrated. Publius, of The Cannabis Papers: ... National Institutes of Health (PubMed) cannabinoid system (CS) articles ...
(Date:3/28/2015)... Take a bite of warm, gooey pepperoni ... tumble into the stomach, ready to break down your ... these acids run amok, triggering a burning sensation in ... than 60 million Americans have heartburn at least once ... and how it can be stopped. , Heartburn or ...
(Date:3/28/2015)... India Network visitor health insurance ... all visitors who purchase the plan before arrival in ... to purchase the insurance program as soon as travel ... for pre-existing medical conditions. Parents and grandparents traveling from ... with serious consequences to their health. Many visitors may ...
Breaking Medicine News(10 mins):Health News:Permanent Life Insurance Quotes Now Offered Through Web Search System at Insurer Website Online 2Health News:Federal Court Overseeing Testosterone Treatment Lawsuits Schedules April Case Management Conference 2Health News:Federal Court Overseeing Testosterone Treatment Lawsuits Schedules April Case Management Conference 3Health News:March Homeostasis: Publius’ Go Endo-Cannabinoid Update ~ New on the Bryan William Brickner Blog 2Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 3
... eCare, an initiative that employs information,and advanced technologies ... care, WILLIAMSBURG, Va., June 18 The ... and Mary proudly announces that,Professor Dorothea La "Chon" ... awards available to a faculty member in a ...
... source; New York City links 7 infections to salmonella ... number of people known to have fallen ill after ... 30 states plus the District of Columbia, U.S. health ... not due to new infections but mainly because some ...
... Corporation,(Nasdaq: AIRM ), the largest air medical ... Executive Officer Aaron Todd and Chief,Financial Officer Trent ... Conference in New York City on Tuesday, June ... can listen to the presentation via a live ...
... strike small percentage of patients , , WEDNESDAY, June 18 ... new side effect associated with the cancer drug Gleevec ... leukemia and gastrointestinal stromal tumors. , In a letter ... New England Journal of Medicine , the doctors describe ...
... seizures, SPOKANE, Wash., June 18 The Epilepsy,Foundation ... this Saturday, June 21 in Spokane at Riverfront Park ... from 9:30 am - 12:30 pm., "Everyone is ... with epilepsy," said Ryan Oelrich, Program Manager. "We are ...
... Berkeley The newly sequenced genome of a dainty, quill-like ... that vertebrates evolved over the past 550 million years through ... ,The late geneticist Susumu Ohno argued in 1970 ... evolution of higher organisms, and Ohno,s theory was the basis ...
Cached Medicine News:Health News:Professor Chon Abraham of the Mason School of Business at The College of William & Mary named Fulbright Scholar 2Health News:Professor Chon Abraham of the Mason School of Business at The College of William & Mary named Fulbright Scholar 3Health News:Professor Chon Abraham of the Mason School of Business at The College of William & Mary named Fulbright Scholar 4Health News:Professor Chon Abraham of the Mason School of Business at The College of William & Mary named Fulbright Scholar 5Health News:Tainted Tomato Cases Jump to 383 People in 30 states, D.C. 2Health News:Tainted Tomato Cases Jump to 383 People in 30 states, D.C. 3Health News:Cancer Drug Gleevec Linked to Muscle Damage 2Health News:Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution 2Health News:Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution 3Health News:Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution 4
... Made with elastic fabric, these head cap ... need to begin testing. Each Electro-Cap System ... the International 10-20 System. When you place ... are using with your head cap system ...
... testing takes you into the OR, ER, or ... of Cadwells new shielded electrodes. Keeping noise low ... paired disc electrode has a special shielded cable ... damaging effects of 60-cycle interference. That means you ...
... The BIOM 3 (Binocular Indirect Ophthalmo-Microscope) incorporates ... microscope and enables a view of up to ... the BIOM 3 the eye may be rotated ... easily viewed. Even surgery through small pupils ...
... have a large body for increased ... 3 centimeters center-to-center) to resist the ... Polarity indicators are molded into the ... our bar electrode styles. Shielded bar ...
Medicine Products: