Navigation Links
Omeros Reports Additional Positive Results from OMS824 Program
Date:9/12/2013

SEATTLE, Sept. 12, 2013 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today announced positive data from the Company's Phase 1 clinical trial evaluating the pharmacokinetics of OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program, further supporting that OMS824 can achieve superior target engagement with lesser side effects compared to other PDE10 inhibitors in development. With these data and the previously announced encouraging results from the OMS824 positron emission tomography (PET) clinical trial, Omeros is advancing OMS824 into Phase 2 clinical programs. OMS824 selectively inhibits PDE10, an enzyme expressed in areas of the brain linked to a wide range of diseases that affect cognition, including Huntington's disease and schizophrenia.

The OMS824 Phase 1 clinical trial included single- and multiple-dose escalation studies that enrolled 100 healthy male subjects: 60 subjects received a single dose of OMS824, 24 subjects received multiple doses for seven to 10 days, and 16 subjects received placebo. The data announced today are at the highest multiple-dose level administered and, at this dose, OMS824 was well tolerated and the only apparent drug-related adverse events were mild. Almost all adverse events were self-limiting, resolving during the 10-day dosing period. In May of this year, Omeros reported that a lower dose evaluated in an ongoing PET clinical trial demonstrated target engagement greater than had previously been reported for any PDE10 inhibitor (an average of approximately 50-percent and a maximum of approximately 70-percent engagement) without the dose-limiting side effects seen with other PDE10 inhibitors. Pharmacokinetic data at the high dose announced today showed an approximately two-fold increase in plasma concentration over that of the dose used in the earlier-reported PET trial. This same high dose l
'/>"/>

SOURCE Omeros Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Omeros Submits OMS302 Marketing Authorization Application to European Medicines Agency
2. Omeros to Present at the Stifel Healthcare Conference 2013
3. Michael A. Jacobsen Joining Omeros as Vice President, Finance and Chief Accounting Officer
4. Omeros Corporation Reports Second Quarter 2013 Financial Results
5. Omeros to Present at the Wedbush 2013 Life Sciences Management Access Conference
6. Omeros Submits New Drug Application to U.S. FDA for OMS302
7. Omeros Reports Positive Results from OMS824 Positron Emission Tomography Clinical Trial
8. Omeros Files Clinical Trial Application for Lead Antibody in MASP-2 Program
9. Omeros Corporation Reports First Quarter 2013 Financial Results
10. Omeros Announces $16.2 Million Registered Direct Offering of Common Stock
11. Omeros Ophthalmology Product OMS302 Granted Eligibility for European Centralized Review
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2015)...  Accuray Incorporated (Nasdaq: ARAY ) announced ... MIM Software Inc. to further develop adaptive therapy ... product portfolios. The new software solution will ... Accuray,s second collaboration with MIM; the previous partnership ... treatment plan review capability, PlanTouch™. "Accuray ...
(Date:4/30/2015)... Diabetes Care ® , Inc. (NASDAQ: TNDM ), a ... and t:flex™ Insulin Pumps, today reported its financial results for ... comparing the first quarter of 2015 to the same period ... million from $8.1 million , t:slim Pump shipments grew ... "Our investment in resources to build the foundation of our ...
(Date:4/30/2015)... 2015   Regulus Therapeutics Inc . (NASDAQ: ... development of innovative medicines targeting microRNAs, today announced that ... quarter ended March 31, 2015 on Thursday, May 7, ... Regulus will host a conference call and webcast ... Daylight Time to discuss its first quarter 2015 financial ...
Breaking Medicine Technology:Accuray Signs Agreement with MIM Software Inc. to Develop Adaptive Therapy Software 2Accuray Signs Agreement with MIM Software Inc. to Develop Adaptive Therapy Software 3Tandem Diabetes Care Reports First Quarter 2015 Financial Results 2Tandem Diabetes Care Reports First Quarter 2015 Financial Results 3Tandem Diabetes Care Reports First Quarter 2015 Financial Results 4Tandem Diabetes Care Reports First Quarter 2015 Financial Results 5Tandem Diabetes Care Reports First Quarter 2015 Financial Results 6Regulus Announces Timing for First Quarter 2015 Financial Results Webcast and Conference Call 2Regulus Announces Timing for First Quarter 2015 Financial Results Webcast and Conference Call 3
... Aug. 8, 2011 Systech International®, the recognized global ... leading systems engineering, automation, and manufacturing optimization services company, ... for the pharmaceutical market in Puerto Rico.  VCG now ... Systech and their extensive customer-base in region. ...
... 2011 - Pharmasset, Inc. (Nasdaq: VRUS ) announces ... to be held August 10 to 11, 2011 at the ... Executive Officer, will provide an overview of the company at ... 9:30 AM (ET). To access a simultaneous webcast ...
Cached Medicine Technology:Systech Selects Vantage Consulting Group as their Sales Agent in Puerto Rico 2Systech Selects Vantage Consulting Group as their Sales Agent in Puerto Rico 3Pharmasset to Present at Canaccord Genuity Growth Conference 2Pharmasset to Present at Canaccord Genuity Growth Conference 3
(Date:5/2/2015)... 02, 2015 Kare Visits LLC. launched in ... busy caregivers. Kare Visits offers relief for caregivers by ... facilities. According to the Caregiver Action Network, eight ... of 20 hours a week caring for an elderly or ... to hire a nurse, a caregiver is now empowered to ...
(Date:5/2/2015)... 02, 2015 ZoomCare, the Portland-based innovator ... plans to offer its new healthcare insurance to individuals ... Personal Health Insurance System is the nation’s first health ... human performance. ZOOM+ Personal Health Insurance was ZoomCare’s first ... that are subject to review and regulation by the ...
(Date:5/1/2015)... (PRWEB) May 02, 2015 IDLife LLC, ... is proud to announce the addition of its newest ... is a life long athlete, growing up in gymnastics ... after college by becoming a personal trainer and helping ... the face of several TV shows highlighting her stunning ...
(Date:5/1/2015)... (PRWEB) May 01, 2015 Pioneer Millworks, ... share the latest in their reclaimed wood products at ... the Jacob Javits Center in NYC this May. Their ... will bring much anticipated texture and color to North ... an explosion of texture and color in the design ...
(Date:5/1/2015)... May 01, 2015 Royal River Natural ... Maine, reports on a new study that found two ... swelling and improved physical function as well as standard ... osteoarthritis of the knee. , The report is part ... for Well Being® ,” which Royal River Natural Foods ...
Breaking Medicine News(10 mins):Health News:Chicagoan Seeks to Transform Industry by Launching an Innovative Elderly Care Solution 2Health News:ZoomCare Applies to be on Oregon Exchange 2Health News:IDLife LLC Announces New Partnership with Fitness Celebrity, Jen Widerstrom 2Health News:Intensely Textured Reclaimed Wood to be Unveiled at ICFF in NYC by Pioneer Millworks 2Health News:Intensely Textured Reclaimed Wood to be Unveiled at ICFF in NYC by Pioneer Millworks 3Health News:New Study Finds Nutrients Ease Arthritis Pain, Retailer Reports 2
... prescription for longevityCOLORADO SPRINGS, Colo., Feb. 2 A ... dying by about 50% compared to runners, walkers and ... study led by Dr. Steven Blair evaluated comprehensive physical ... were enrolled in the Aerobics Center Longitudinal Study (ACLS) ...
... PLYMOUTH MEETING, Pa., Feb. 2 Employers spend more than ... to obesity - dubbed the world,s number one health threat ... of work, are more prone to injury and accidents and ... there is a guidepost to help employers address this issue. ...
... University,s M.S. in Mental,Health Counseling program is ... and Related Educational Programs (CACREP), an independent,accrediting agency ... accredits counselor preparation master,s degree programs., Walden ... a,CACREP-accredited M.S. degree in Mental Health Counseling online. ...
... 13,000 biological and biomedical scientists will gather for the ... Convention Center in New Orleans, April 18 -April 22. ... scientific concepts and research findings shaping future and current ... an unparalleled opportunity to hear from colleagues working on ...
... Name Change Signals Rapid Evolution of Technology, ... the innovative health care analytics company that ... and other health care leaders, is changing ... http://www.newscom.com/cgi-bin/prnh/20090202/PH65375LOGO )In addition to the ...
... Ocean Spray Supports the Go Red for Women Movement by ... 2 Ocean Spray is joining the American Heart Association,s ... million in support of the cause. While heart disease is ... is also largely preventable. Throughout the month of February, Go ...
Cached Medicine News:Health News:New Study Reveals Swimming Can Cut Men's Risk of Dying in Half 2Health News:New Study Reveals Swimming Can Cut Men's Risk of Dying in Half 3Health News:Health Advocate Releases Obesity White Paper: Strategies and Programs to Reduce Obesity in the Workplace 2Health News:Health Advocate Releases Obesity White Paper: Strategies and Programs to Reduce Obesity in the Workplace 3Health News:Walden University's M.S. in Mental Health Counseling Program Receives CACREP Accreditation 2Health News:Walden University's M.S. in Mental Health Counseling Program Receives CACREP Accreditation 3Health News:Experimental Biology 2009 meets April 18-22 2Health News:Experimental Biology 2009 meets April 18-22 3Health News:Experimental Biology 2009 meets April 18-22 4Health News:Experimental Biology 2009 meets April 18-22 5Health News:Health Care Analytics Innovator SafeMed Becomes Anvita Health, Expands Software Solutions 2Health News:Health Care Analytics Innovator SafeMed Becomes Anvita Health, Expands Software Solutions 3Health News:Health Care Analytics Innovator SafeMed Becomes Anvita Health, Expands Software Solutions 4Health News:Ocean Spray Shows Its Love for Heart Health with American Heart Association Partnership 2
Integra Epilepsy grid electrodes are thin and flexible for easier placement and to conform to the curvature of the cortical surface. Lead tunneling is done using a 14-gauge tunneling needle (ET-2)....
...
... Electrodes feature exceptional quality and design to ... seizure recording technology. Neurosurgeons worldwide consider these ... flexible available. Our electrodes come in many ... 4-contact strips to 64-contact grids. Their bodies ...
... designed for laboratories looking for time and ... system operation in terms of easy reagent ... and on-board stability., ,URISYS 2400 is ... walk-away capability for medium to high volume ...
Medicine Products: