Navigation Links
Omeros Files Orphan Drug Application for Treatment of Atypical Hemolytic Uremic Syndrome with OMS721
Date:4/17/2013

vation pathways, known as the lectin pathway. Importantly, inhibition of MASP-2 does not appear to interfere with the antibody-dependent classical complement activation pathway, which is a critical component of the acquired immune response to infection, and its abnormal function is associated with a wide range of autoimmune disorders. MASP-2 is generated by the liver and is then released into the circulation. Adult humans who are genetically deficient in one of the proteins that activate MASP-2 do not appear to be detrimentally affected by the deficiency. Therefore, Omeros believes that it may be possible to deliver MASP-2 antibodies systemically.

Omeros also believes that it has identified the proteins that activate the complement system's alternative pathway, which is linked to a wide range of immune-related disorders. In addition to its lectin pathway inhibitors, the Company is advancing the development of antibodies that would block activation of the alternative pathway alone or in combination with the lectin pathway.

About Omeros Corporation

Omeros is a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing products targeting inflammation, coagulopathies and disorders of the central nervous system. The Company's most clinically advanced product candidates, OMS302 for lens replacement surgery and OMS103HP for arthroscopy, are derived from its proprietary PharmacoSurgery™ platform designed to improve clinical outcomes of patients undergoing a wide range of surgical and medical procedures. Omeros has five clinical development programs. Omeros may also have the near-term capability, through its GPCR program, to add a large number of new drug targets and their corresponding compounds to the market. Behind its clinical candidates and GPCR platform, Omeros is building a diverse pipeline of protein and small-molecule preclinical programs targeting inflammation, coagulopathies and central nervous syst
'/>"/>

SOURCE Omeros Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Omeros Announces that GPR17 Antagonists Improve Function in Model of Multiple Sclerosis
2. Omeros Announces Positive OMS721 Data in Model of Thrombotic Microangiopathy
3. Omeros to Present at the 2013 Future Leaders in the Biotech Industry Conference
4. Omeros Announces Toxicology Data that Support Advancing MASP-2 Inhibitor into Clinical Trials
5. Omeros Announces Successful Completion of PDE10 Phase 1 Multiple Ascending Dose Trial
6. Omeros Elucidates Mechanism of its PDE7 Inhibitors in Addiction
7. Omeros to Present at the Cowen and Company 33rd Annual Health Care Conference
8. Omeros Announces Toxicology Study Data from MASP-2 Inhibitor
9. Omeros Announces Positive OMS302 Safety Data in Phase 3 Clinical Trial
10. Omeros Announces Encouraging Data from Phase 1 Clinical Trial for PDE10 Program
11. Omeros to Present at the 24th Annual Piper Jaffray Health Care Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... , Sept. 18, 2014  ADM Tronics Unlimited, ... , Ph.D. to its corporate Advisory Board for ... instructor at the Harvard Medical School and Visiting ... He received his Masters degree in Electronics Engineering ... from the University of Bologna. After spending a year ...
(Date:9/18/2014)... Sept. 18, 2014  A $3 million grant from ... University of Michigan to establish a national center of ... Center for Aging Research at U-M will focus on ... slow the effects of aging and postpone diseases in ... that can help develop medications that may help people ...
(Date:9/18/2014)...  Neurotrope, Inc. (OTCQB: NTRP) today announced the appointment ... the Company,s Board of Directors, effective September 12, 2014. ... the Board of seven members. Dr. Altstiel will also ... and a member of the Audit and Compensation Committees ... Scientific Advisory Board, a position he has held since ...
Breaking Medicine Technology:ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 2ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 3$3 M grant funds Paul F. Glenn Center for Aging Research at the University of Michigan 2$3 M grant funds Paul F. Glenn Center for Aging Research at the University of Michigan 3Larry D. Altstiel, M.D., Ph.D. Joins Neurotrope Board of Directors 2Larry D. Altstiel, M.D., Ph.D. Joins Neurotrope Board of Directors 3Larry D. Altstiel, M.D., Ph.D. Joins Neurotrope Board of Directors 4
... 20, 2011 Reportlinker.com announces that a new ... Rheumatoid Arthritis Market Forecast ... launch of novel oral drugs and reformulations of ... the seven major markets, rising from $12bn in ...
... Sept. 20, 2011 Reportlinker.com announces ... is available in its catalogue: ... Therapy (HRT) - Pipeline Assessment and ... http://www.reportlinker.com/p0617091/Post-Menopausal-Hormone-Replacement-Therapy-HRT---Pipeline-Assessment-and-Market-Forecasts-to-2018.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Therapy ...
Cached Medicine Technology:Rheumatoid Arthritis Market Forecast 2Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 2Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 3Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 4Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 5Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 6Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 7Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 8Post-Menopausal Hormone Replacement Therapy (HRT) - Pipeline Assessment and Market Forecasts to 2018 9
(Date:9/18/2014)... Kent, WA (PRWEB) September 18, 2014 ... at Lake Meridian Chiropractic are pleased to announce that Dawn ... the 24-year-old clinic. Dr. Saggau looks forward to Ms. ... operational and administrative talents will make her a key contributor. ... unique combination of educational, professional, and personal experiences that ...
(Date:9/18/2014)... September 18, 2014 Memorial Cardiac ... history this week by performing the first ever, adult ... (United Network for Organ Sharing) approval to launch the ... of only two programs in South Florida. , ... Dr. Enrique Gongora, Medical Director of the Adult ...
(Date:9/18/2014)... 2014 (HealthDay News) -- Exposure to diverse communities may ... Hearing different languages in the park or ... learn from people who are different from them, researchers ... adults, are often biased against interacting with and learning ... Woodward, a University of Chicago psychology professor, said in ...
(Date:9/18/2014)... Reinberg HealthDay Reporter , THURSDAY, Sept. ... outbreak in West Africa is starting to spread faster than ever, ... cases of the deadly viral infection were reported in just one ... than 5,300, with roughly half of those reported in the past ... deaths now tops 2,600. WHO has estimated that as many ...
(Date:9/18/2014)... It’s been just a few short weeks ... bunion splint to website visitors, but already the response has ... absolutely delighted. It is perfect and I find it sooo ... THANK YOU FOR LISTENING!!!" Another user compared the original ... used to slip to the end of my toe. Now ...
Breaking Medicine News(10 mins):Health News:Lake Meridian Chiropractic of Kent, WA Announces that Dawn Kelly Has Been Promoted to the Position of Office Manager 2Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 2Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 3Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 4Health News:Study: Exposure to Diversity Might Boost Baby's Social Skills 2Health News:New Ebola Cases Top 700 in Just One Week, Officials Report 2Health News:New Ebola Cases Top 700 in Just One Week, Officials Report 3Health News:Feedback for the New Bunion Bootie Design Feedback is Already Pouring In, and Bunion Sufferers Love It 2Health News:Feedback for the New Bunion Bootie Design Feedback is Already Pouring In, and Bunion Sufferers Love It 3
... Jan. 10 (HealthDay News) -- Women exposed to plasticizers and ... and to have lower birth-weight babies, according to a new ... age 30, who were pregnant between 2002 and 2006. More ... women who provided information on how long it took them ...
... Reporter , MONDAY, Jan. 10 (HealthDay News) -- Having babies ... second child, new research suggests. The highest risk was ... sibling. Babies conceived within 12 to 23 months and 24 ... a heightened risk of autism, although the risk was not ...
... HealthDay Reporter , MONDAY, Jan. 10 (HealthDay News) -- ... brain on Saturday will likely cause some permanent damage, but ... might be. However, doctors at University Medical Center in ... shooting are already encouraged by her ability to follow simple ...
... romantic partners are not quintessentially masculine, women in their ... men than are women paired with George Clooney types. ... become more attracted to their partners, a recent study ... concludes. Meanwhile, a man,s intelligence has no effect ...
... Steven Reinberg HealthDay Reporter , SUNDAY, Jan. ... fluoxetine (best known by the brand name of Prozac) ... stroke sufferers, French researchers have found. Not surprisingly, ... to depression after their stroke, the study found. ...
... who have to undergo dialysis see their lives inevitably ... of life perceived by these kidney patients has improved ... Basing this as her starting point, Dr Begoa Ruiz ... with dialysis (hospitalised haemodialysis treatment and domiciliary peritoneal dialysis) ...
Cached Medicine News:Health News:Closely Spaced Pregnancies Might Up Autism Risk: Study 2Health News:While Doctors Are Optimistic, Prognosis for Wounded Congresswoman Is Unclear 2Health News:While Doctors Are Optimistic, Prognosis for Wounded Congresswoman Is Unclear 3Health News:While Doctors Are Optimistic, Prognosis for Wounded Congresswoman Is Unclear 4Health News:Men with macho faces attractive to fertile women, researchers find 2Health News:Men with macho faces attractive to fertile women, researchers find 3Health News:Prozac May Speed Physical Rehabilitation After Stroke 2Health News:Prozac May Speed Physical Rehabilitation After Stroke 3Health News:Ph.D. thesis shows why patients subjected to dialysis face their illness in different ways 2Health News:Ph.D. thesis shows why patients subjected to dialysis face their illness in different ways 3
... Tecoflex stents that save inventory, shelf space, ... ureteral lengths from 22 cm to 28 ... Quadra-Coil to glide over any guidewire and ... provide ease of placement and patient comfort ...
... for temporary internal drainage from the ... sterile in peel-open packages. Intended for ... advised; C-Flex® and Sof-Flex® stents must ... (6) months; silicone stents must not ...
... Classic Double Pigtail Ureteral Stents have ... that maximizes migration. They also feature ... and cost savings. Each Classic ... one Classic Double PigTail Ureteral Stent ...
... internal drainage from the ureteropelvic ... filiform stent assembly provides one ... peel-open packages. Intended for one-time ... advised; stent must not remain ...
Medicine Products: