Navigation Links
Omeros Announces Positive OMS721 Data in Model of Age-Related Macular Degeneration
Date:11/5/2013

SEATTLE, Nov. 5, 2013 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today announced positive data using OMS721, the lead human monoclonal antibody in Omeros' mannan-binding lectin-associated serine protease-2 (MASP-2) program, in a well-established animal model of neovascular age-related macular degeneration (AMD), which is characterized by abnormal growth of new blood vessels behind the retina of the eye and is a leading cause of vision loss in individuals over 60 years of age. Omeros is currently completing a Phase 1 clinical trial of OMS721 in healthy subjects.

The study was conducted by Dr. Puran S. Bora and colleagues at the Jones Eye Institute, Pat and Willard Walker Eye Research Center of the University of Arkansas for Medical Sciences. In this animal model, new vessel growth in the eye is induced by laser treatment. Systemically administered OMS721 resulted in less than half of the blood vessel development compared to placebo treatment. The study included an antibody to vascular endothelial growth factor (VEGF) that also reduced blood vessel growth, and OMS721 outperformed the anti-VEGF treatment. Anti-VEGF treatment is the current mainstay of commercially available therapies for neovascular AMD.

Omeros controls the worldwide rights to MASP-2 and all therapeutics targeting MASP-2, a novel pro-inflammatory protein involved in activation of the complement system – an important component of the immune system. The complement system plays a role in the inflammatory response to tissue damage or microbial infection, and both human genetic and animal studies have linked the complement system to AMD development. OMS721 selectively inhibits MASP-2, blocking the lectin pathway of the complement system while leaving intact the classical pathway, or the acquired immune response to infection. Omeros recent
'/>"/>

SOURCE Omeros Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. FDA Grants Orphan Drug Designation to Omeros OMS824 for Huntingtons Disease
2. Omeros Chosen to Present at NewsMakers in the Biotech Industry 2013 Conference
3. Omeros Reports Initiation of Phase 2 Clinical Trial with OMS824
4. Omeros Reports Additional Positive Results from OMS824 Program
5. Omeros Submits OMS302 Marketing Authorization Application to European Medicines Agency
6. Omeros to Present at the Stifel Healthcare Conference 2013
7. Michael A. Jacobsen Joining Omeros as Vice President, Finance and Chief Accounting Officer
8. Omeros Corporation Reports Second Quarter 2013 Financial Results
9. Omeros to Present at the Wedbush 2013 Life Sciences Management Access Conference
10. Omeros Submits New Drug Application to U.S. FDA for OMS302
11. Omeros Reports Positive Results from OMS824 Positron Emission Tomography Clinical Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... CHICAGO , Sept. 19, 2014  4WEB Medical ... of 3D-printed foot and ankle osteotomy implants on ... and Ankle Society annual meeting in Chicago ... for all of a surgeon,s osteotomy needs with 74 size ... wedge systems had smaller offerings of only 15 to 18 ...
(Date:9/19/2014)... Sept. 19, 2014 Merck (NYSE: MRK ), ... and Canada , is teaming with celebrity chef ... Logra Tus Metas , an educational program encouraging Hispanics with type ... a key treatment goal to help reduce the risk of serious ... are at a higher risk for developing type 2 diabetes than ...
(Date:9/19/2014)... Sept. 19, 2014  Diplomat, the nation,s largest independent ... Dreyer to the Board of Directors on September ... will also serve as chair of the Audit Committee. ... of accounting, financial, compliance and operating experience in the ... served as chief financial officer, chief operating officer and ...
Breaking Medicine Technology:4WEB Medical Unveils 3D-Printed Osteotomy Truss System 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5David Dreyer Appointed to Diplomat Board of Directors 2
(Date:9/22/2014)... Back pain is a daily reality for ... instant powerful pain relief without taking a dangerous drug may ... have made this very possible. Enter on-line retailer Variety4Kicks, and ... Tens Unit electronic back massager. This premium quality, ... relief each and every day, in a way that's ...
(Date:9/22/2014)... Plugin creators from Pixel Film Studios ... 3D particle emitter made specifically for Final Cut ... plugin to a video adds an element of computer ... Film Studios. “ProSparkle gives users a 3D Sparkle emitter ... ProSparkle users are given total control over creating a ...
(Date:9/22/2014)... The Center for Health Affairs is ... as one of the NorthCoast 99 Award winners. This ... for top talent. This award recognizes these 99 organizations ... that support the attraction, retention and motivation of top ... development and training, compensation and rewards, success and performance, ...
(Date:9/22/2014)... 2014 A Case Management Order (CMO) ... the discovery phase for testosterone lawsuit claims pending in ... of Illinois. Wright & Schulte LLC notes ... submit initial disclosures about potential witnesses and documents in ... continue negotiating the topics in Plaintiff Fact Sheets before ...
(Date:9/22/2014)... Reflecting their position as the leading provider ... Doors and Gates is now offering ornamental iron gates ... offers quality wrought iron ornamental gates that bring elegance ... range of ornamental doors that suit varied purposes and ... ornamental doors wherein their specifications and requirements are meticulously ...
Breaking Medicine News(10 mins):Health News:Online Retailer Variety4Kicks Announces An Over The Counter Tens Unit For Back Pain Relief Is Now Available For Sale 2Health News:Announcing a new ProSparkle Particle Emitter Pack from Pixel Film Studios for Final Cut Pro X Professionals 2Health News:The Center for Health Affairs Named to 2014 NorthCoast 99 List 2Health News:The Center for Health Affairs Named to 2014 NorthCoast 99 List 3Health News:Judge Issues CMO For Testosterone Lawsuits Alleging Heart Attacks and Strokes Caused By "Low T" Drugs Such As Androgel 2Health News:Judge Issues CMO For Testosterone Lawsuits Alleging Heart Attacks and Strokes Caused By "Low T" Drugs Such As Androgel 3Health News:Judge Issues CMO For Testosterone Lawsuits Alleging Heart Attacks and Strokes Caused By "Low T" Drugs Such As Androgel 4Health News:Judge Issues CMO For Testosterone Lawsuits Alleging Heart Attacks and Strokes Caused By "Low T" Drugs Such As Androgel 5Health News:Strictly Doors and Gates Now Adding Ornamental Iron Gates to Their Products Line 2
... Opus Healthcare Solutions, Inc., a ... today that OpusMobility(R) runs on ... ) , (Logo: http://www.newscom.com/cgi-bin/prnh/20080325/LATU040LOGO ) Opus ... or Wi-Fi connections on all smart phone devices ...
... January 13, 2009 A benchmarking study ... evaluated contemporary hospital glycemic management in United ... are suboptimal and do not meet current American ... The retrospective cohort study was based upon a ...
... its annual Molecular Imaging Summit to introducing the new ... Hilton Clearwater Hotel, Clearwater, Fl. In part, the program ... Network, which was designed to facilitate cost-effective drug development ... 2, 3 and 4 therapeutics clinical trials. In addition, ...
... health care policyWASHINGTON, Jan. 13 The RAND ... policymakers and interested parties with a unique way ... consequences of health care reform proposals certain to ... beyond. COMPARE (Comprehensive Assessment of Reform Efforts) is ...
... ATLANTA, Jan. 13 Vendormate nearly tripled its customer,base ... in 42 states across the,U.S. in part because of ... help mitigate the risk of supply chain,interruptions. , ... and financial service,providers in particular are anxious about their ...
... Family,Services, Inc. No. 2851 on its annual ranking of ... marks the second consecutive year that,Access Family Services has ... the most,comprehensive look at the most important segment of ... whole, these companies represent,the backbone of the U.S. economy. ...
Cached Medicine News:Health News:OpusMobility(R) Clinical Information System Runs on Google G1 Smart Phone 2Health News:OpusMobility(R) Clinical Information System Runs on Google G1 Smart Phone 3Health News:Annual SNM MI summit introduces the clinical trials network 2Health News:RAND Launches Unique Tool to Evaluate Health Care Proposals 2Health News:RAND Launches Unique Tool to Evaluate Health Care Proposals 3Health News:RAND Launches Unique Tool to Evaluate Health Care Proposals 4Health News:Economic Uncertainty Fuels Vendormate Growth in 2008 2Health News:Access Family Services, Inc. Makes the List for the Second Year in a Row! Access Family Services 2008 Ranks No. 2851 on the Inc. 5000 With Three-Year Sales Growth of 128% 2
The CD Horizon M10 Spinal System provide spine surgeons comprehensive solutions for the treatment of spinal deformities, trauma reconstruction, and degenerative conditions....
... VIASYS Neurocare - continues the ... diagnosis. Exceptional convenience and speed. Superior ... ,VasoGuard delivers features you won't find ... for cuff attachment and testing. Up ...
... Spine System Evolution offers the latest ... variety of spinal pathologies including degenerative lumbar ... It is also intended for the treaent ... of the L5-S1 vertebra. Levels of pedicle ...
Multiwindow transcranial and peripheral Doppler system....
Medicine Products: