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Octapharma Targeting the Major Risk of Hemophilia Treatment - FVIII Antibodies
Date:8/26/2009

ant human cell line products in various stages of development.

During the symposium, possible advantages of using a human cell line for recombinant FVIII production were presented. Those include the absence of the rodent antigenic epitopes Gal-1,3-Galactose and N-glycolyl-neuraminic-acid on the FVIII-protein, which could lead to a reduced immunogenicity compared to currently marketed recombinant factor VIII products that are all derived from hamster cell lines and also to a potentially increased tolerability.

Octapharma AG

Octapharma AG is headquartered in Lachen, Switzerland, the third largest plasma products manufacturer in the world and has been committed to patient care and medical innovation for over 25 years. Octapharma's core business is the development, production and sale of high quality human protein therapies from both human plasma and human cell lines, including immune globulin intravenous (IGIV). In the U.S., Octapharma's IGIV product, octagam(R) (immune globulin intravenous [human] 5%), is used to treat disorders of the immune system, and Octapharma's Albumin (Human) is indicated for the restoration and maintenance of circulating blood volume. Octapharma employs over 3,000 people and has biopharmaceutical experience in 80 countries worldwide, including the United States, where Octapharma USA
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