Navigation Links
Octapharma Targeting the Major Risk of Hemophilia Treatment - FVIII Antibodies
Date:8/26/2009

art Kreuz, M.D. of the Hemophilia Comprehensive Care Centre at Johann Wolfgang Goethe University Hospital in Frankfurt, Germany. "Successful ITI leads to normalization of the FVIII half-life, allows fully effective on-demand replacement therapy and prophylaxis, with consequent improvement in the patient's quality of life and a marked reduction in the cost of treatment."

The Octapharma-sponsored symposium "From Humans to Humans - Introducing the First Recombinant FVIII Produced From a Human Cell Line" was chaired by Edward G.D. Tuddenham, M.D., Director of The Katharine Dormandy Haemophilia Center & Thrombosis Unit in London, and Johannes Oldenburg, M.D., Ph.D., Chairman and Director of the Institute of Experimental Haematology and Transfusion Medicine in Bonn, Germany.

"Twenty years after the start of clinical trials with rFVIII concentrates expressed by hamster cells, a new rFVIII compound has recently entered clinical studies," Dr. Tuddenham said. "The primary goal behind the development of this new rFVIII was to reduce the overall immunogenic challenge (and resultant inhibitor formation) to the hemophilia patient during rFVIII replacement therapy. An essential part of this strategy was the development of a human rFVIII protein expressed in a human cell-based protein expression system instead of using existing hamster-derived cell lines."

The symposium highlighted the benefits of using a human cell-based protein; preclinical characterizations and some of the functional properties of the first recombinant factor VIII (rFVIII) from a human cell-line; and the planned global clinical development program with the new rFVIII derived from human cells. The investigational new drug application for Octapharma's human cell line rFVIII was filed in the U.S. in May 2008. Clinical trials started in Russia in Spring 2009 and are expected to start in the U.S. later this year. Additionally, Octapharma has other recombin
'/>"/>

SOURCE Octapharma AG
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Octapharma Accepting Applications for Research Grants on Immunotherapy, Coagulation Disorders and Critical Care
2. Plasma Products Safe Despite Swine Influenza Outbreak, Assures International Biopharmaceutical Company Octapharma
3. Dendreon Initiates Phase 1 Clinical Trial of Small Molecule Targeting TRPM8 in Cancer
4. Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrines PS-Targeting Antibodies
5. Raptor Pharmaceuticals Provides Update on Targeting Platforms
6. Medarex Receives Milestone Payment for Investigational Antibody Targeting Integrin Receptors
7. MedImmune Advances Asthma Program with Start of a Phase 2 Trial in Europe and Australia and First U.S.-Based Clinical Trial for Antibody Targeting IL-13
8. Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrines anti-PS Vascular Targeting Antibodies
9. Dutch Top Institute Allocates 150 Million Euro to R&D Projects Targeting Early Diagnosis and Treatment of Disease
10. Genaera Announces MedImmune Initiation of Phase 2a Trial of Antibody Targeting Interleukin-9 in Patients with Asthma
11. MedImmune Advances Clinical Development of Antibody Targeting Interleukin-9 in Patients with Asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... , Dec. 17, 2014  IGI Laboratories, Inc. (NYSE ... closing of its offering of $125 million aggregate principal ... "Notes").  The Notes were offered and sold only to ... Securities Act of 1933, as amended (the "Securities Act"). ... rate of 3.75% per year, payable semiannually in arrears ...
(Date:12/15/2014)... December 15, 2014 ... 19. und 20. Februar sind alle akkreditierten ... MEDICINE ECOSYSTEM PARTNER PROGRAMM ™ 2015 in ... Diese Tagung soll dazu beitragen, ... geben, die neue profitablen Unternehmensdienstleistungen, die für ...
(Date:12/15/2014)... --Research and Markets , ... announced the addition of the "Cardiac Guidewires - ... offering. Global Guidewires sector is projected to reach ... accounts for nearly 35% (2015) of the ... approximately 25% (2018). Asia-Pacific is ...
Breaking Medicine Technology:IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 2IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 4Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4
... CARLOS, Calif, April 11, 2007 /PRNewswire-FirstCall/ --,Nuvelo, ... from a study,of NU206 (R-Spondin1), a secreted ... acts as a specific and potent,stimulator of ... damaged in patients with inflammatory bowel,conditions, including ...
... 10, 2007 - The two most,prevalent forms of ... share a common cause, according to researchers at,Stanford ... network in the brain, may also be associated ... very different, the,end result for the brain seems ...
Cached Medicine Technology:Nuvelo Announces Publication of NU206 Study Results in,Gastroenterology 2Nuvelo Announces Publication of NU206 Study Results in,Gastroenterology 3Nuvelo Announces Publication of NU206 Study Results in,Gastroenterology 4Fragile X, Down Syndromes Linked to Faulty Brain Communication,Stanford Researcher Finds 2Fragile X, Down Syndromes Linked to Faulty Brain Communication,Stanford Researcher Finds 3Fragile X, Down Syndromes Linked to Faulty Brain Communication,Stanford Researcher Finds 4
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... example of the Bush Administration promoting, politics over a sound health ... oversight of the federal family planning program and the health of ... ... National Abortion,Federation (NAF) denounces the appointment of Dr. Susan Orr as ...
... 40|86 Strategic Income,Fund (NYSE: CFD ) declared a ... holders of record at the close of business on ... closed-end investment management,company. The Fund,s primary investment objective is ... prospectus, the Fund intends to,distribute substantially all of its ...
... State Senate,Committee passed legislation today (October 17) that would enable,motorcyclists ... bid to rid riders of their helmets, special interest groups ... motorcyclists,can buy their way out of a helmet. The ... Senate in the near,future. The bill was passed by the ...
... standard treatment best against the facial paralysis, study finds , , ... is no better at easing a form of facial paralysis ... , The fact that acyclovir may not be a new, ... say, but on the other hand, many people afflicted with ...
... defect exists in men, it could lead to new treatments, ... defect in a gene that,s essential for the formation of ... of sperm from being able to penetrate an egg. , ... at Chapel Hill, was based on research with mice. But ...
... Governors,University (http://www.wgu.edu ) is now offering its ... managers and nurse educators. These,scholarships are designed to ... become educators, managers, and leaders in various healthcare,settings. ... and,M.S. in Nursing-Leadership and Management degree programs., ...
Cached Medicine News:Health News:National Abortion Federation Denounces the Appointment of Dr. Orr to Oversee Federal Family Planning Funds 2Health News:Michigan Senate Committee Votes in Favor of 'Opt-Out' Option for State's Helmet Law; AAA Says Deaths and Injuries Will Increase 2Health News:Antiviral Won't Improve Bell's Palsy Outcome 2Health News:Gene Mutation Key to Infertility in Male Mice 2Health News:Nursing Scholarships Offered by Western Governors University for Master's Degree Programs 2
Complete calibration kits are available for both pH and manometry systems....
... formulated buffers are available from ... antimony catheters. All buffers are ... internal or external reference, single ... are available in 250ml bottle ...
... formulated buffers are available from ... antimony catheters. All buffers are ... internal or external reference, single ... are available in 250ml bottle ...
Flexilog custom medical carts are configured to suite the requirements of FLEXILOG motility system users. With locking wheels and storage drawers, our carts are suitable for any care provider in any ...
Medicine Products: