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Obesity Therapeutics to 2019 - Safety Concerns Hinder Drug Performance Despite Large Market Opportunity
Date:9/16/2013

nsing Agreement with Takeda Pharma 686.1.3 Palatin Technologies Extends License Agreement with AstraZeneca 696.1.4 Zealand Pharma Enters into Licensing and Collaboration Agreement with Boehringer Ingelheim 696.2 Co-development Deals 706.2.1 Isis Enters into Collaboration Agreement with Ortho-McNeil 716.2.2 Orexigen Therapeutics Enters into Co-development Agreement with Takeda Pharma for Contrave 717 Appendix 727.1 References 727.2 Abbreviations 767.3 All Pipeline Drugs by Phase 797.3.1 Discovery 797.3.2 Preclinical 807.3.3 Phase I 847.3.4 Phase II 857.3.5 Phase III 867.3.6 Pre-Registration 867.4 Market Forecasts to 2019 877.4.1 Global 877.4.2 The US 877.4.3 UK 887.4.4 France 887.4.5 Germany 887.4.6 Italy 897.4.7 Spain 897.4.8 Japan 897.5 Methodology 907.6 Secondary Research 907.7 Therapeutic Landscape 907.8 Epidemiology-Based Forecasting 917.9 Market Size by Geography 927.10 Pipeline Analysis 937.11 Contact Us 937.12 Disclaimer 93

1.1 List of Tables

Table 1: BMI Classifications 10Table 2: Key Components of Pathways Thought to be Related to Obesity 14Table 3: Treatment Options Dependent on BMI 16Table 4: Obesity Therapeutics, Leading Brand Names of Phentermine 18Table 5: Efficacy Results* for Qsymia at 52 Weeks 21Table 6: Changes in Key Safety Parameters in Patients Treated with Qsymia 21Table 7: Sales Data for Xenical ($m), 2008–2011 23Table 8: Efficacy Results for Orlistat as an Initial and Maintenance Therapy 24Table 9: Safety Results of Orlistat 25Table 10: Efficacy Results for Belviq 27Table 11: Placebo-adjusted Safety Results for Belviq 27Table 12: Obesity Therapeutics Market, Global, Common Molecular Targets in the Obesity Pipeline 35Table 13: Obesity Therapeutics Market, Global, Average Clinical Trial Size for the Most Common Modes of Action Amongst Pipeline Drugs, 2006–2013 3
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