Navigation Links
Obesity Common in Children with Heart Disease

PHILADELPHIA, Nov. 1 /PRNewswire-USNewswire/ -- Obesity is common in children with heart disease, a population already at increased risk of a shortened life expectancy.

More than 25 percent of children with congenital and acquired heart disease are overweight or obese, say researchers from The Children's Hospital of Philadelphia and Children's Hospital, Boston in a study released in the current issue of Pediatrics. While this 25 percent prevalence is similar to the rate found in the general population, the researchers stress that health risks from obesity are added to the children's separate risks from their underlying heart disease.

Activity restrictions, whether or not they are recommended by physicians, may play a role in the development of obesity in this patient group, say the research team, adding that doctors may need to counsel families on safe and appropriate exercise routines for their children.

"Children with congenital heart disease may have unique risk factors which may contribute to the development of obesity," said Nelangi M. Pinto, M.D., a pediatric cardiologist now at University of Utah formerly of The Children's Hospital of Philadelphia where the research was conducted and primary investigator of this study. "The long-term impact of superimposed obesity on children with heart disease is unknown but is likely to increase morbidity and mortality as it does in adults with heart disease."

The Children's Hospital of Philadelphia clinicians collaborated with researchers from Children's Hospital Boston, to review the medical records from a sample of 2,921 patients between ages six and 19 years of age who visited one of the hospitals for cardiology outpatient care in 2004. Of the 2,921 samples, 1,523 children had either acquired or congenital heart disease.

Roughly half of the sample who had no significant heart disease constituted the control group in the study. The rate of overweight and obesity in these control patients was no different from that found in the general population of children, as measured by the Centers for Disease Control and Prevention.

Among the children with heart disease, those with heart transplants, rhythm problems and mild heart disease had a similar prevalence of obesity to the clinic control group. The only subgroup of children with heart disease with a significant lower prevalence of overweight and obesity were those who had undergone the Fontan operation to treat highly complex forms of congenital heart disease.

Those children had a prevalence of 15.9 percent, compared to the over 25 percent rate found in both clinic control group and the heart patients as a whole.

The researchers noted that children who have the Fontan operation often have chronic growth and development problems, but the rate of obesity, nearly 1 in 6, was still very concerning.

The researchers also found that discussions about weight were relatively uncommon during cardiology clinic visits. "Awareness and discussion of weight control, exercise and other lifestyle issues must become an important part of the evaluation of all children with heart disease during cardiology visits," said Meryl S. Cohen, M.D., a pediatric cardiologist at The Children's Hospital of Philadelphia and senior author on this study. "It is also important to note that activity restrictions are not solely determined by cardiologists but may also be initiated by parents or self-imposed by the children themselves."

Drs. Pinto and Cohen's coauthors were Bradley S. Marino, M.D., M.P.P., M.S.C.E.; Gil Wernovsky, M.D.; Kristen Hyland, and Stanley O. Dunn, Jr., all of The Children's Hospital of Philadelphia; and Sarah D. de Ferranti, M.D., M.P.H; Meena Laronde, R.N., and Amy Z. Walsh, R.N., of Children's Hospital Boston.

The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 430-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit

Contact: Joey Marie McCool

(267) 426.6070

SOURCE The Children's Hospital of Philadelphia
Copyright©2007 PR Newswire.
All rights reserved

Related medicine technology :

1. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
2. Amylin Pharmaceuticals to Present New Data from Broad Diabetes and Obesity Programs at ADA 2007
3. Genaera to Present Preclinical Data on Trodusquemine for the Treatment of Obesity at the American Diabetes Association 67th Scientific Sessions
4. Common Preterm Labor Drug Has More Side Effects Than Alternative, Finds Study from Packard Childrens Hospital and Stanford
5. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
6. Encouraging Clinical Activity of GSKs Novel Cancer Immunotherapeutic Confirmed in Phase II Study in Patients with Most Common Form of Lung Cancer
7. Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant
8. Researchers Discover a Common Variation in a Gene Segment that Increases the Risk for Prostate Cancer
9. Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million Annually
10. One-Third of Patients Discontinue Common Breast Cancer Therapy
11. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
Post Your Comments:
(Date:6/24/2016)... NAMUR , Belgium , ...  (NYSE MKT: VNRX), today announced the appointment of ... Board of Directors as a Non-Executive Director, effective ... the Company,s Audit, Compensation and Nominations and Governance ... Board, Dr. Futcher will provide independent expertise and ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published ... unfamiliar with. The article goes on to state that individuals are now more comfortable ... less common operations such as calf and cheek reduction. The Los Angeles area medical ...
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
Breaking Medicine News(10 mins):