Navigation Links
ObeTherapy Announces the Publication of Results Obtained with one of its Lead Compounds on a New Target for the Treatment of Obesity and Type II Diabetes
Date:12/4/2012

PARIS, December 4, 2012 /PRNewswire/ --

ObeTherapy, a company focusing on the treatment of obesity and type II diabetes,  announces the publication of results that validate a new therapeutic target associated with  "starvation" human phenotype and a novel small-molecule candidate for the treatment of obesity and type II diabetes,

The article, entitled: Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment, http://dx.plos.org/10.1371/journal.pone.0049612, Numerous genes associated with obesity have been targeted over the years to treat such a condition. However, none of these has provided an effective treatment for either obesity or type II diabetes.  Many commercial drugs that target such genes have been withdrawn from the market on accounts of lack of efficacy, lack of specificity, and/or toxicity. It is therefore essential to identify new gene targets that are specific, non-redundant and associated to lean phenotype.  

Research at ObeTherapy aims to identify genes that are implicated in a "lean" human phenotype by addressing the following questions:  Are there any genetic diseases that produce a "lean phenotype"? If so, is such a condition dependent upon a single gene (i.e., is it a monogenic disease)? Is such a gene tissue-specific? Is it redundant?

Congenital enteropeptidase deficiency is an extremely rare pathology that satisfies the foregoing criteria.  Patients suffering from such a condition can eat ad libitum without gaining weight; indeed, if left untreated, they will lose weight and ultimately starve (starvation phenotype).  Thus, partial inhibition of enteropeptidase with an approriate drug should allow obese patients to nourish themselves normally, yet assimilate only a fraction of the total energy consumed during a meal. These patients would thus retain the plea
'/>"/>

SOURCE ObeTherapy Biotechnology
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
2. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
3. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
4. Misonix Announces New Distribution Agreement For Panama
5. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
6. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
7. Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter
8. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
9. Masimo Announces New Low-Profile Infant and Neonatal Pulse Oximetry Sensors
10. Anthera Announces the Completion of Patient Dosing in Phase 2b PEARL-SC Study
11. STAAR Surgical Announces First Quarter 2012 Results Release Date and Conference Call and Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... -- Hologic, Inc. (NASDAQ: HOLX ) today announced ... 28, 2014. Third Quarter Financial Highlights and ... million, reflecting operational growth of 0.5% and a positive ... in the prior year. , Revenues grew in ... revenues grew 3.5%. , GYN Surgical revenues grew ...
(Date:7/30/2014)... July 30, 2014  Cepheid (Nasdaq: ... contract with Premier will end on September 30, ... will be able to continue their relationship with ... MedAssets, Novation, and ROi, in addition to the ... Cepheid. "Cepheid has always recognized and ...
(Date:7/30/2014)... , July 30, 2014 CryoLife, Inc. (NYSE: ... focused on cardiac and vascular surgery, announced today that ... dividend for the third quarter 2014 of $0.03 per ... of $0.03 per share will be paid on September ... of September 12, 2014.  The ex-dividend date for the ...
Breaking Medicine Technology:Hologic Announces Third Quarter Fiscal 2014 Operating Results 2Hologic Announces Third Quarter Fiscal 2014 Operating Results 3Hologic Announces Third Quarter Fiscal 2014 Operating Results 4Hologic Announces Third Quarter Fiscal 2014 Operating Results 5Hologic Announces Third Quarter Fiscal 2014 Operating Results 6Hologic Announces Third Quarter Fiscal 2014 Operating Results 7Hologic Announces Third Quarter Fiscal 2014 Operating Results 8Hologic Announces Third Quarter Fiscal 2014 Operating Results 9Hologic Announces Third Quarter Fiscal 2014 Operating Results 10Hologic Announces Third Quarter Fiscal 2014 Operating Results 11Hologic Announces Third Quarter Fiscal 2014 Operating Results 12Hologic Announces Third Quarter Fiscal 2014 Operating Results 13Hologic Announces Third Quarter Fiscal 2014 Operating Results 14Hologic Announces Third Quarter Fiscal 2014 Operating Results 15Hologic Announces Third Quarter Fiscal 2014 Operating Results 16Hologic Announces Third Quarter Fiscal 2014 Operating Results 17Cepheid Updates Status Of Premier Group Purchasing Organization (GPO) Agreement 2Cepheid Updates Status Of Premier Group Purchasing Organization (GPO) Agreement 3CryoLife Announces Quarterly Cash Dividend for the Third Quarter 2014 2CryoLife Announces Quarterly Cash Dividend for the Third Quarter 2014 3
...  19, 2011 The Emergency Medicine Patient Safety ... upcoming 1st Annual Patient Safety Summit in Las Vegas, ... Safety in Emergency Care: Excellence in Outcomes, (Twitter ... on solving the patient safety challenges associated with providing ...
... 19, 2011 Medical Care Technologies Inc. ... industry, is pleased to announce that is has signed ... Limited ("OWII"), a private Hong Kong investment holding company ... opening and operating private pediatric clinics throughout China. ...
Cached Medicine Technology:National Leaders in Emergency Medicine and Patient Safety to Address Future Opportunities and Challenges in Emergency Care 2Medical Care Technologies Inc. Signs Letter of Intent for Joint Venture in China 2Medical Care Technologies Inc. Signs Letter of Intent for Joint Venture in China 3
(Date:7/30/2014)... (PRWEB) July 30, 2014 Good ... featured in an upcoming episode of Innovations with ... Discovery Channel. Dates and show times TBA. , ... Good Neighbor Community Services’ vision to redefine the ... individualized and dynamic services. Through passion, innovation, determination, ...
(Date:7/30/2014)... HealthDay Reporter WEDNESDAY, July ... States, at least 2,000 Americans die from extreme heat or ... waves, heat stroke or sun stroke caused nearly one-third of ... according to the U.S. Centers for Disease Control and Prevention. ... body heat -- accounted for 63 percent of those weather-related ...
(Date:7/30/2014)... HealthDay Reporter WEDNESDAY, July 30, 2014 (HealthDay ... excess pounds may want to team up with their child, ... a supervised behavioral modification program gained less weight than their ... average difference of about four pounds over two years). Their ... years, according to the study. "In a nutshell, we ...
(Date:7/30/2014)... happen in an instant: A small child pulls up on ... injured when the furniture tips over. "Every parent or ... and imagine what could tip over, fall off walls and ... a reality," Dr. Alex Rosenau, president of the American College ... Between 2009 and 2011, roughly 43,000 people ended up in ...
(Date:7/30/2014)... Volunteers from the Church of Scientology of Denmark have ... massive distribution of Truth About Drugs education ... Strøget, the famous Copenhagen walking street. Popular with ... ambiance, some quarter of a million people stroll down ... These activities are part of a coordinating effort by ...
Breaking Medicine News(10 mins):Health News:Good Neighbor Community Services to be Featured in an Upcoming Episode of Innovations With Ed Begley, Jr. 2Health News: Extreme Weather Kills 2,000 in U.S. Each Year: CDC 2Health News: Extreme Weather Kills 2,000 in U.S. Each Year: CDC 3Health News:Make Kids' Weight Loss a Family Affair, Study Suggests 2Health News:Make Kids' Weight Loss a Family Affair, Study Suggests 3Health News:Make Kids' Weight Loss a Family Affair, Study Suggests 4Health News:Tip-Over Furniture Can Kill Kids 2
... development collaboration between leading Australian Institutions, the Children,s ... of Melbourne and Bio-Link Partners Ltd., has been ... New Therapy Grant winners. This prestigious research grant ... focussed on development and commercialisation of small molecule ...
... to other parts of the body, known as metastasis, is ... cancer. Although patients with early stage, small, breast tumours have ... per cent of them will eventually develop distant metastases, and ... blood vessels is the major route for cancer spreading ...
... DATATRAK International,Inc. (Nasdaq: DATA ), a technology ... the clinical trials industry, today announced that,it received ... Nasdaq Stock Market,("Nasdaq"), notifying the Company that for ... 2008, the bid price of the Company,s common ...
... HighPoint Solutions LLC,a premier provider of ... signed an agreement with a global specialty ... N Managed Care and Government Pricing,System., ... finding,systematic approaches to effectively comply with government ...
... announced a $100 million (AUD) initiative to build ... assist in discovering cures and therapies for such ... ,flu pandemics. , In making the announcement at ... Diego, Premier Brumby said the Victorian government is ...
... Live Call-ins, Interactive Blogs on Topics From Holistic Health to ... ... RATON, Fla., June 18 BocaRaton.com and The Bites!,Network will ... "The Insight" featuring three hosts who will,discuss various topics dealing ...
Cached Medicine News:Health News:Dynamin drug discovery team win prestigious international epilepsy grant 2Health News:Dynamin drug discovery team win prestigious international epilepsy grant 3Health News:Improving understanding of cell behavior in breast cancer 2Health News:DATATRAK International, Inc. Receives Notice From Nasdaq 2Health News:DATATRAK International, Inc. Receives Notice From Nasdaq 3Health News:HighPoint Solutions Signs Deal to Implement Model N Managed Care and Government Pricing System for Specialty Pharmaceutical Company 2Health News:Premier Brumby announces plans to build largest life sciences supercomputer facility 2Health News:Premier Brumby announces plans to build largest life sciences supercomputer facility 3Health News:A South Florida Premiere 2
BD Visitec IOL Manipulator (Fenzl), blunt tip angled 45, 12.0 mm from end, fits 0.20 mm diameter holes and larger (3/bx, 1 bx/ca). For positioning intraocular lenses. Sure grip handles hand ridge ind...
... IOL Manipulator (Jaffe-Maltzman), blunt tip, ... end, fits 0.20 mm diameter ... intraocular lenses, (3/bx, 1 bx/ca), ... Sure grip handles hand ridge ...
Sinskey lens manipulator, straight. Also available in titanium....
Straight, with guard. Ideal for multi-directional manipulation....
Medicine Products: