Date:11/3/2011

the United States and may be different from similar non-GAAP financial measures used by other companies. The non-GAAP financial measure disclosed by the Company is not meant to be considered superior to or a substitute for results of operations prepared in accordance with GAAP. Management uses Adjusted EBITDA (EBITDA adjusted for stock based-compensation, deferred revenue recognized, manufacturing transition costs and other non-cash expenses) to understand operational cash usage.  The Company believes the non-GAAP financial measure provides useful and supplementary information allowing investors greater transparency to one measure used by management.  The non-GAAP financial measure is meant to supplement, and to be viewed in conjunction with, GAAP financial measures.  The non-GAAP financial measure is reconciled to the most comparable GAAP financial measure below.

NxStage Medical, Inc.Condensed Consolidated Statements of Operations(in thousands, except per share data)(unaudited)Three Months EndedNine Months EndedSeptember 30,September 30,2011201020112010Revenues

$55,903$45,033$160,235$129,449Cost of revenues

36,36330,073103,79788,914Gross profit

19,54014,96056,43840,535Operating expenses:Selling and marketing

9,4468,45228,02525,034Research and development

3,3883,13210,6949,369Distribution

4,7093,78813,29810,831General and administrative

5,7086,02316,75016,604Total operating expenses

23,25121,39568,76761,838Loss from operations

(3,711)(6,435)(12,329)(21,303)Other expense:Interest expense

(1,186)(1,176)(3,513)(3,432)Other (expense), net

(146)(341)(342)(128)(1,332)(1,517)(3,855)(3,560)Net loss before income taxes

(5,043)(7,952)(16,184)(24,863)Provision for income taxes

235212654556Net loss

$ (5,278)$ (8,164)$ (16,838)$ (25,419)Net loss per share, basic and diluted

$   (0.10)$   (0.17)$
(0.31)$
(0.54)Weighted-average
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SOURCE NxStage Medical, Inc. Copyright©2010 PR Newswire. All rights reserved

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