Nuvo Research presents positive Phase III study results for Pennsaid at leading rheumatology ...( MISSISSAUGA ON Oct. 27 / Nuvo Res...),Health

MISSISSAUGA, ON, Oct. 27 /PRNewswire-FirstCall/ - Nuvo Research Inc. (TSX: NRI), a Canadian drug development company focused on the research and development of drug products delivered to and through the skin using its topical and transdermal drug delivery technologies, today announced that study results showing that Pennsaid, Nuvo's topical diclofenac solution, is an effective treatment option for the symptoms of osteoarthritis of the knee, with an improved safety profile compared to oral diclofenac, were detailed in a poster presentation at the 2008 American College of Rheumatology Scientific Meeting in San Francisco.

The lead author of the presentation was Dr. Lee Simon, Associate Clinical Professor of Medicine, Harvard Medical School. This was the first presentation to a medical and scientific audience of the Phase III clinical study results, which were originally announced by the Company upon study completion in January 2006.

"Presenting at a prestigious event such as the American College of Rheumatology Scientific Meeting provides Nuvo with a forum to share our compelling Pennsaid clinical data with medical and scientific leaders," said Dr. Brad Galer, Vice President and General Manager of Nuvo's Pain Group. "As we move closer to Pennsaid's approval by the U.S. FDA, it is important that the professional rheumatology community be aware of what we believe is the strongest clinical efficacy and safety evidence of any topical NSAID formulation for the treatment of osteoarthritis. We believe that this data supports the conclusion that Pennsaid, once approved, will be the best-in-class product available in the U.S."

"These results confirm and extend previous studies and show that this novel topical diclofenac solution is efficacious for the relief of symptoms in patients with symptomatic knee osteoarthritis," said Dr. Marc C. Hochberg, Head, Division of Rheumatology & Clinical Immunology at the University of Maryland School of Medicine. "F
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