Navigation Links
Novexel Starts Phase II Clinical Trial With NXL103 in Adults With Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Date:11/6/2009

nti-MRSA antibacterials when they wish to switch from intravenous (IV) to oral treatment, a key step prior to a patient being able to be discharged from the hospital.

NXL103, as a member of the Streptogramin class of antibiotics, has a unique mode of action, with its two components acting synergistically to inhibit the bacterial ribosome. Its spectrum of activity indicates its potential to be effective in the treatment of ABSSSI, including those caused by resistant pathogens such as MRSA.

In late 2008, Novexel announced positive results from a Phase II clinical trial evaluating NXL103 in the treatment of community acquired pneumonia (CAP).

Iain Buchanan, Novexel's CEO, said, "The start of this Phase II trial with NXL103 is another important step in the growth of the company. There is a clear need for products that can be used to manage the release of patients from hospital by allowing them to be switched from intravenous to oral therapy."

Notes to Editors

About NXL 103

NXL103 is a novel oral antibiotic made up of two streptogramin antibiotics, linopristin and flopristin, which act synergistically to inhibit the bacterial ribosome. NXL103 is a bactericidal antibiotic and in vivo studies have shown that this novel antibiotic is not affected by either beta-lactam or common macrolide resistance mechanisms. Positive results for a Phase II trial with NXL103 in the treatment of community acquired pneumonia (CAP) were reported towards the end of 2008. NXL103 is currently in a Phase II trial for the treatment of ABSSSI.

About ABSSSI

ABSSSI (Acute Bacterial Skin and Skin Structure Infections) are infections that involve deeper tissue or require surgical intervention (e.g. cellulitis, major cutaneous abscesses, and infected wounds) or are associated with a significant underlying disease that complicates response to therapy. A variety of pathogens may
'/>"/>

SOURCE Novexel
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Novexel to Present Four Posters at the 19th European Congress of Clinical Microbiology and Infectious Diseases in Helsinki
2. Novexels NXL104/ceftazidime Combination Commences Second Phase II Clinical Trial in Hospital Patients With Complicated Intra-Abdominal Infections (cIAIs)
3. Novexels NXL104/ceftazidime Combination Commences Phase II Clinical Trial in Hospital Patients With Complicated Urinary Tract Infections
4. Novexel to Present Five Posters at the Joint Annual Interscience Conference on Antimicrobial Agents and Chemotherapy and the Infectious Disease Society of America (ICAAC/IDSA) Meeting
5. Novexel Reports Positive Phase II Trial Results With NXL103 in Adult Patients With Community Acquired Pneumonia
6. AMT Starts Development LPLChip(TM) With Progenika
7. American Association for Homecare Proposes Strong Anti-Fraud Measures in Medicare, Applauds HHS Testimony Today That Pledges to "Stop Fraud Before it Starts"
8. R-Tech Ueno Starts Early Phase II Clinical Trial for RK-023
9. BioCis Pharma Starts a Phase I Clinical Trial With a New Cancer Drug
10. Intercell Starts a Phase I Clinical Trial for a New Streptococcus pneumoniae Vaccine
11. GeoVax Starts Injections for Phase 2a Human HIV/AIDS Vaccine Trial in USA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... 31, 2014 Vermillion, Inc. (NASDAQ: VRML), a multivariate ... hold a conference call on Thursday, August 14, 2014, at ... quarter ended June 30, 2014. Financial results will be issued ... Vermillion,s Chairman, President and CEO James LaFrance will ... Date: Thursday, August 14, 2014 Time: 4:30 p.m. ...
(Date:7/31/2014)... YORK , July 31, 2014 TB ... better, faster and affordable treatments for tuberculosis (TB), announced ... Vice President, Market Access. Ms. Robertson joins the organization ... company,s business in Sub-Saharan Africa and Eastern ... oversee the TB Alliance,s efforts to ensure beneficial new ...
(Date:7/31/2014)... NEW YORK , July 31, 2014 ... the eighth annual Prix Galien USA ... biomedical industry,s highest accolade and recognizes the technical, scientific ... and devices. This year brings the highest ... Galien USA . Nominees include biomedical ...
Breaking Medicine Technology:Vermillion Sets Second Quarter 2014 Conference Call for Thursday, August 14, 2014 2TB Alliance Names Elana Robertson Senior Vice President, Market Access 2TB Alliance Names Elana Robertson Senior Vice President, Market Access 3The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 2The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 3The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 4The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 5
... ... C Clarification of Oncogenic Pathways ... Potential Benefit in Liver Transplantation, MILAN, April 26 , - Systems Biology ... Meeting of the European,Association for the Study of the Liver (EASL), experts reported advances ...
... YORK, April 24 PulmoBioTech Inc. (OTC,Bulletin Board: PLMO) ... the areas that it will be investigating as part ... are:, 1. Efficacy Binding Studies 2. ... 4. Pyrogenicity 5. Immunological Testing 6. ...
Cached Medicine Technology:Basic Science Discoveries Yield Progress in Hepatology 2Basic Science Discoveries Yield Progress in Hepatology 3Basic Science Discoveries Yield Progress in Hepatology 4PulmoBioTech Announces Details of Its Regulatory Approval Experiments 2PulmoBioTech Announces Details of Its Regulatory Approval Experiments 3
(Date:7/31/2014)... (PRWEB) July 31, 2014 Developer Jamestown, ... on its Ponce City Market project in Atlanta’s ... Sears, Roebuck & Company building into best-in-class office, housing, ... OxBlue reviewed Jamestown’s experience with their construction webcam service ... , Jamestown wanted a construction camera for ...
(Date:7/31/2014)... Goshen, IN (PRWEB) July 31, 2014 In ... and increasingly difficult to get. Snoring and sleep apnea (a ... stops) rob people and their bed partners of the rest ... to 45% of the population snores and 20 million people ... only 10% have been diagnosed and treated; and of those ...
(Date:7/31/2014)... In many states and counties across the country, ... necessary life saving drugs. This requirement is for the safety ... high number of ambulances without proper security procedures. , In ... and even replaces the vital pain killers with saline. Later, ... the case in Baraboo, Wisconsin last November. According to court ...
(Date:7/31/2014)... Adventist Health System, which is ... Florida Hospital Tampa, Florida Hospital Carrollwood, Florida Hospital ... Pinellas, Florida Hospital Wesley Chapel, Florida Hospital Zephyrhills, ... Heartland Medical Center Lake Placid and Florida Hospital ... Most Wired Hospitals and Health Systems, which is ...
(Date:7/31/2014)... NV (PRWEB) July 31, 2014 Weblify has ... after 4 years of development and testing. The result ... monetized websites in as little as 5 minutes without knowing ... full Weblify review , Shane Michaels, an SEO expert, agrees ... quickly. “I’ve seen a lot of web site builders ...
Breaking Medicine News(10 mins):Health News:OxBlue Construction Webcam Proves Valuable Tool for Developer, Consumers on Historic Ponce City Market Project 2Health News:OxBlue Construction Webcam Proves Valuable Tool for Developer, Consumers on Historic Ponce City Market Project 3Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:New MedixSafe Alert - Ambulances Must Have A Medical Safe, Narcotics Cabinet, or Drug Locker 2Health News:Florida Hospital West Florida Region is Among the Most Wired Hospitals and Health Systems in the United States 2Health News:Weblify Review Exposes Ricky Mataka And His New Site Building Platform 2Health News:Weblify Review Exposes Ricky Mataka And His New Site Building Platform 3
... 29 Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN ... 13-D filing with the Securities and Exchange Commission from ... their intent to nominate a slate of five directors ... meeting. Amylin has not yet received the required notice ...
... DALLAS Jan. 29, 2009 Mice whose fat cells were ... "healthy" obesity when fed a high-fat diet, researchers at UT Southwestern ... but healthy mice lacked a protein called collagen VI, which normally ... a cage around a water balloon. The findings appear online and ...
... major public health problem. A new study examined the ... OA progression and symptoms. CS, unlike other chondroitin sulfate ... been approved as a prescription symptomatic slow acting drug ... published in the February issue of Arthritis & ...
... year,s worst city for asthmatics, experts say , , THURSDAY, Jan. ... "Asthma Capital of the United States," according to the Allergy ... most challenging places to live for people with the respiratory ... the top of this year,s list due to a number ...
... You Care" Contest Invites Participants to Share and ... CVS/pharmacy, the nation,s leading retail pharmacy, today announced ... Care" contest created to celebrate and honor caregivers ... caregivers and others to submit stories of caring ...
... , ... Irvine, CA (Vocus) January 29, 2008 -- ... improvement programs in a meaningful way, LifeMasters Supported SelfCare, Inc. has ... demonstration project targeting Medicare and Medicaid recipients in South Florida. , ...
Cached Medicine News:Health News:UT Southwestern researchers identify protein that may explain 'healthy' obesity 2Health News:Chondroitin slows progression and relieves symptoms of knee osteoarthritis 2Health News:St. Louis Ranked America's 'Asthma Capital' 2Health News:CVS/pharmacy Announces National Contest for Stories of Extraordinary Caregiving 2Health News:CVS/pharmacy Announces National Contest for Stories of Extraordinary Caregiving 3Health News:LifeMasters Offers Financial Incentives to Florida Physicians for Participation in Disease Management Programs 2Health News:LifeMasters Offers Financial Incentives to Florida Physicians for Participation in Disease Management Programs 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: