Navigation Links
Novelos Therapeutics And Academic Collaborators Present Three Posters At 2012 World Molecular Imaging Congress
Date:9/7/2012

nding.  We may determine such a dose based on an efficacy signal or an acceptable safety profile in the Phase 1b trial and/or upon calculating it from ongoing PET imaging trials in cancer patients with LIGHT (since PET imaging is quantitative, enabling determination of tumor radiation exposure at a given dose level).  Preclinical experiments in vitro (in cell culture) and in more than a dozen in vivo (in animals) models have demonstrated selective killing of cancer cells along with a benign safety profile.  In view of HOT's selective uptake and retention in a wide range of solid tumors and in cancer stem cells, its single-agent efficacy in animal models and its non-specific mechanism of cancer-killing (radiation), we are first developing HOT as a monotherapy for solid tumors with significant unmet medical need.

About Novelos Therapeutics, Inc.
We are a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer.  Our cancer-targeted compounds are selectively taken up and retained in cancer cells, including cancer stem cells, versus normal cells.  Thus, our therapeutic compounds appear to directly kill cancer cells while minimizing harm to normal cells.  This offers the potential for a paradigm shift in cancer therapy by providing efficacy versus all three major drivers of mortality in cancer: primary tumors, metastases and stem cell-based relapse.  I-124-CLR1404 (LIGHT) is a small-molecule cancer-targeted PET imaging agent.  We believe LIGHT has first-in-class potential and Phase 1-2 clinical trials are ongoing across 11 solid tumor indications.  I-131-CLR1404 (HOT) is a small-molecule, broad-spectrum, cancer-targeted molecular radiotherapeutic that delivers cytotoxic radiation directly and selectively to cancer cells and cancer stem cells.  We believe HOT also has first-in-class potential.  HOT Phase 1b dose-escalation trial is ongoing and we expect HOT to en
'/>"/>

SOURCE Novelos Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
2. Novelos Therapeutics Successfully Completes First Cohort In Phase 1b Solid Tumor Trial With I-131-CLR1404 (HOT) Cancer-Targeted Molecular Radiotherapeutic
3. Novelos Therapeutics Prices $5.4 Million Public Offering
4. Novelos Therapeutics to Present at LHA Life Sciences & Medical Technologies Virtual Conference on June 28
5. Novelos Therapeutics to Present at Rodman & Renshaw 14th Annual Healthcare Conference on September 11
6. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
7. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
8. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
9. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
10. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
11. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... , July 11, 2014  Kindred Hospital Houston ... announce the opening of its new outpatient wound ... services to people with chronic, hard to heal ... can lead to amputation, lower leg wounds related ... delayed closure, and traumatic injury wounds which are ...
(Date:7/11/2014)... Australia , July 11, 2014  Australian drug ... announced that it has raised A$19.3 million via a ... Europe , the U.S., Asia ... A$3 million from a share purchase plan (SPP) to ... million will be made in two tranches. ...
(Date:7/11/2014)... , July 11, 2014 ... 4,396.20, down 0.52%, the Dow Jones Industrial Average finished the ... at 1,964.68, down 0.41%. The losses were broad based as ... The S&P 500 Health Care Sector Index ended the day ... in the last one month. Investor-Edge has initiated coverage on ...
Breaking Medicine Technology:Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4
(Date:7/11/2014)... (PRWEB) July 11, 2014 Ticket Down is a ... in Mountain View, CA. Over the years Luke Bryan ... accolades. Not only does he do well at award shows, but ... of the most anticipated tours of the genre and this summer ... few artists can compare to the popularity and success that is ...
(Date:7/11/2014)... Ticket Down is a reliable ... Train Amphitheatre in Wheatland, CA. In the Sacramento ... what the Sleep Train Amphitheatre can do for music fans. ... over the course of its existence and can seat 18,500 ... in Wheatland (Sacramento metro area) will host the “That’s My ...
(Date:7/11/2014)... Riverside Health System became the first provider of ... late 2012 and now, in partnership with Williamsburg Landing, will ... Williamsburg and Newport News region. , Also known as life ... independent older adults who wish to remain in their homes ... continuing care services as well as control over the cost ...
(Date:7/11/2014)... Austin, TX (PRWEB) July 11, 2014 ... to their staff. Jim Siddons joins the agency as ... Siddons graduated in 1994 with a Bachelor’s Degree in ... years of industry experience and will manage everything from ... bonds for trucking to the specialized needs for those ...
(Date:7/11/2014)... 2014 Europe is one of the ... cultivated-and hence, irrigated land area. The agricultural sector is ... for around 30.0% of the total water use. The ... the southern region, but far from negligible in most ... for over 60.0% of the water use in most ...
Breaking Medicine News(10 mins):Health News:Luke Bryan Tickets Shoreline Amphitheatre in Mountain View, CA: Ticket Down Slashes Ticket Prices for Luke Bryan in Mountain View at the Shoreline Amphitheatre 2Health News:Luke Bryan Tickets Shoreline Amphitheatre in Mountain View, CA: Ticket Down Slashes Ticket Prices for Luke Bryan in Mountain View at the Shoreline Amphitheatre 3Health News:Luke Bryan Tickets Sleep Train Amphitheatre in Wheatland, CA (Sacramento): Ticket Down has Slashed Ticket Prices on Luke Bryan in Wheatland at Sleep Train 2Health News:Luke Bryan Tickets Sleep Train Amphitheatre in Wheatland, CA (Sacramento): Ticket Down has Slashed Ticket Prices on Luke Bryan in Wheatland at Sleep Train 3Health News:Riverside and Williamsburg Landing Partner to Offer First of Its Kind Service to Virginians Who Want to Age in Place 2Health News:Riverside and Williamsburg Landing Partner to Offer First of Its Kind Service to Virginians Who Want to Age in Place 3Health News:Riverside and Williamsburg Landing Partner to Offer First of Its Kind Service to Virginians Who Want to Age in Place 4Health News:Europe Micro Irrigation System Market Driven by Growing Environmental Concerns and Decreasing Water Availability - New Report by MicroMarket Monitor 2Health News:Europe Micro Irrigation System Market Driven by Growing Environmental Concerns and Decreasing Water Availability - New Report by MicroMarket Monitor 3
... bedside patient safety solutions -SAN DIEGO, April 3 ... handheld barcode point-of-care (BPOC) solutions ... Sweeney has been appointed Chairman and CEO.(Logo: ... CEO of eight healthcare service companies including Bridge ...
... boost strength in other ways, researchers say , , FRIDAY, April ... mass in octogenarian women but still helped them lift more ... University in Indiana finds. , , The six ... for three months on a machine designed to strengthen the ...
... F C, s * ... , Although recent media attention has focused on the presence of ... Protection Agency and the U.S. Food and Drug Administration (FDA) have ... appropriate for all consumers, including sensitive sub-populations like infants. Trace ...
... Inc. (Nasdaq: MEDQ ) has announced it has ... of Sales and Marketing. Gold will be responsible for ... of MedQuist. "We are pleased to have Alan join the ... brings an extensive knowledge and an in-depth understanding of healthcare ...
... poorer scores on cognitive tests , , FRIDAY, April 3 (HealthDay News) ... life span may be taking a toll on the brains of ... shows that women aged 47 to 74 who tested positive for ... or bones (an indication of cumulative exposure over the life span) ...
... & Spa,Group, Inc. (OTC Bulletin Board: SOKF) announced the ... April 1, 2009. The latest SOKO Spa began,offering "pre-opening" ... more,than 500 Spa members since that date. , ... Blessing Hot Spring Business Club,No.332, Xinyang Rd., Daoli District, ...
Cached Medicine News:Health News:James M. Sweeney Named Chairman and CEO of IntelliDOT 2Health News:James M. Sweeney Named Chairman and CEO of IntelliDOT 3Health News:James M. Sweeney Named Chairman and CEO of IntelliDOT 4Health News:Muscle Mass Won't Grow in Women Over 80 2Health News:International Formula Council (IFC) Reassures Parents about Perchlorate and the Safety of Infant Formula 2Health News:MedQuist Names Alan J. Gold as Senior Vice President, Sales and Marketing 2Health News:Accumulated Lead May Affect Older Women's Brains 2Health News:SOKO Fitness & Spa Group, Inc. Opens Xinyang Spa in Harbin 2
... UniBloc weighing mechanism for speed, ... stability control, analog display modes, multiple ... percent measure functions, auto print, and ... data from built-in clock. Built-in, ...
TOPLOAD 320/0.01G, BL320S. Touch-key external calibration only. Requires calibration weights (either 200g or 300g). 120/240V A/C adapter, Lock-down Ring, In-use Protective Cover....
... - Battery Powered (6 size AA required). ... (g, ct, oz, ozt, GN, dwt, mom, ... and Percent Measure functions, Auto Print. Optional ... AC adapter may be ordered for AC ...
... (6 size AA required). Fast, Lightweight Strain ... ozt, GN, dwt, mom, dwt, tael), Specific ... functions, Auto Print. Optional hook (321-34532-03) available ... be ordered for AC Operation of ELB. ...
Medicine Products: