Navigation Links
Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders
Date:12/6/2008

study was the percentage of patients with Grade 2 or higher bleeding, calculated using the WHO Bleeding Scale. Grade 2 bleeding is clinically significant bleeding that does not require a red blood cell transfusion. Grade 2 or higher bleeding occurred in 71 percent of patients in the low-dose arm, 69 percent in the medium-dose arm, and 70 percent in the high-dose arm. Grade 3 or higher bleeding, which generally does require treatment by red blood cell transfusion, was seen in 12 percent of patients in the low-dose arm, 9 percent in the medium-dose arm, and 10 percent in the high-dose arm. Grade 4 bleeding, the most serious, was seen in 3 percent, 2 percent, and 2 percent of patients in the low-dose, medium-dose, and high-dose arms, respectively. The median number of red blood cell transfusions (usually given for anemia) was four in each treatment arm. Treatment dose did not affect the frequency of any bleeding grade in any of the four patient groups.

A Therapeutic Platelet Transfusion Strategy Without Routine Prophylactic Transfusion is Feasible and Safe and Reduces Platelet Transfusion Numbers Significantly: Preliminary Analysis of a Randomized Study in Patients After High-DoseChemotherapyand Autologous Peripheral Blood Stem Cell Transplantation [Abstract#286]

Hannes Wandt, MD, Klinikum Nuremberg Nord, Nuremberg, Germany

This is the first worldwide randomized study showing that one-quarter to one-third of all platelet transfusions were given unnecessarily in the past and can be reduced in the future without any harm to patients following high-dose chemotherapy and autologous stem cell transplantation, according to Dr. Wandt.

This multicenter, randomized trial found that the development of major
'/>"/>

SOURCE American Society of Hematology
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Novel Technology Breaks Through Cancer Pain
2. Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers Diarrhea Patch Vaccine
3. Pharmacopeia Assists the World Health Organization in the Discovery of Novel Therapeutics for the Treatment of Malaria
4. Quark Pharmaceuticals Files Patent Application Covering Novel Chemical Modifications to its RNAi Molecules
5. Ardea Biosciences, Inc. Announces Completion of Phase 1 Clinical Trials of Novel Investigational HIV Drug RDEA806
6. The Lancet Publishes Major Phase 3 Study on Novel Oral Direct Thrombin Inhibitor
7. Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress
8. Phase 2 Clinical Studies Initiated for a Novel Therapeutic Candidate Identified Through Pharmacopeia Collaboration
9. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
10. ECLIPSE Data on Effects of Otsukas Investigational Novel Treatment, Tolvaptan, on Advanced Heart Failure Patients Hemodynamics and Urine Output Featured in Heart Failure Society of Americas Late Breaking Trials
11. Ardea Biosciences, Inc. Presents Results of Phase 1 Studies of RDEA806, a Novel NNRTI for HIV, at 47th ICAAC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Aug. 21, 2014  eRelevance Corporation ( www.erelevancecorp.com ... today that it has completed integration with Nextech, ... Plastic Surgery and Dermatology practices. "Integration ... to healthcare practices using Nextech," stated Bob ... "Using information from the EMR we are able ...
(Date:8/21/2014)... YORK , Aug. 21, 2014  Publicis Groupe ... Shannon Hartley , Managing Partner and Healthcare Industry Group ... PharmaVoice 100, which recognizes the most inspiring people in ... are leaders in research and development, marketing, technology, creativity, ... agency in 2006 as a partner in its leading ...
(Date:8/21/2014)... TORONTO , Aug. 21, 2014 /CNW/ - The Canadian ... a new comic series designed to educate children about the ... epilepsy.  The Medikidz Explain Epilepsy comic series tells ... who is navigating middle school while living with epilepsy. ... 100 Canadians, there is still so much misinformation and lack ...
Breaking Medicine Technology:eRelevance Corporation Integrates with Nextech Electronic Medical Records 2Shannon Hartley Shines in PharmaVOICE 100 2Action Heroes Harness Powers to Educate Children About Epilepsy 2Action Heroes Harness Powers to Educate Children About Epilepsy 3
(Date:8/21/2014)... with advanced laryngeal cancer appear to have better ... nonsurgical chemoradiation. , Author: Uchechukwu C. Megwalu, M.D., ... Mount Sinai, New York, and colleagues. , Background: ... are diagnosed each year and squamous cell carcinoma ... Prior to 1991, total surgical removal of the ...
(Date:8/21/2014)... TX (PRWEB) August 21, 2014 Improv ... 20 entertained residents with dementia at Silverado Turtle Creek ... Troupe, which consists of entertainers ranging from ages 10 ... time they perform their 40-minute set. The troupe's philosophy ... it universal and allows them to touch audiences regardless ...
(Date:8/21/2014)... DURHAM, NC -- Researchers have pinpointed the environmental source ... in Southern California for decades. It literally grows on ... project of a 13-year-old girl, who spent the summer ... Angeles hardest hit by infections of the fungus named ... Cryptococcus , which encompasses a number of species ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 The City ... plans for entertainment and programming for its inaugural “Re:Imagine ... Sunday, October 12, 2014, from 11 a.m. to 4 ... to all cars and the downtown will be filled ... curated by Community Arts Resources (CARS), for all to ...
(Date:8/21/2014)... only is eating better and exercising healthy for people with ... year, a new study finds. The study, led by ... Forest Baptist Medical Center in Winston-Salem, N.C., included more ... Participants ranged in age from 45 to 76, ... program" focused on diet and exercise, or to a standard ...
Breaking Medicine News(10 mins):Health News:Surgery associated with better survival for patients with advanced laryngeal cancer 2Health News:Unicorn Clearance Improv Troupe Brings Laughter to Residents with Dementia at Silverado Memory Care 2Health News:Fungus deadly to AIDS patients found to grow on trees 2Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 2Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 3Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 4Health News:Getting Healthier a Big Money-Saver for People With Diabetes 2
... savings comes an extra,hour of sleep, but how ... to the daily cup of coffee, early birds ... the Flower Promotion Organization at:, http://media.medialink.com/WebNR.aspx?story=34055 ) ... that study participants reported being happier and more ...
... Stryker Corporation,(NYSE: SYK ) announced today that it will participate in the ... 8:30 a.m. Mountain Standard Time Credit ... November 27, 2007 - 12:30 p.m. ... Care Conference New York, New York ...
... University Class Tests Benefits of Chewing Gum During Exam, ... can,be particularly stressful on college students as they struggle ... (Photo: http://www.newscom.com/cgi-bin/prnh/20071101/AQTH193 ) "It,s common practice ... and pull all-nighters in preparation for exams," says Adrinda,Kelly, ...
... Centers, Inc.,("GNC" or the "Company"), announced today that it ... third quarter 2007 financial,results at 11 a.m. EST Thursday, ... the U.S., dial 1-888-895-5479, and,outside the U.S. dial 1-847-619-6250. ... webcast of the call will also be available,through the ...
... awards,Ashaway,s horse-assisted rehabilitative therapy with Premier Center Program ... ... Nov. 1 Turning Pointe,Therapeutic Riding has again been recognized ... the Handicapped Association (NARHA),the national standard bearer for therapeutic equine ...
... Kids,Indiana Action Fund launched an independent, direct ... supporting local elected officials who,have championed smoke-free ... - D) and Scott Keller (District 16 ... in passing Indianapolis, smoke-free,ordinance. The Indianapolis smoke-free ...
Cached Medicine News:Health News:Stryker to Present at Investor Conferences 2Health News:As Exams Loom, Students Find Hope in a 'Stick' 2Health News:As Exams Loom, Students Find Hope in a 'Stick' 3Health News:As Exams Loom, Students Find Hope in a 'Stick' 4Health News:Turning Pointe Therapeutic Riding Recognized for Excellence in Providing Equine-Assisted Therapies to People with Disabilities 2Health News:Tobacco-Free Kids Indiana Action Fund Launches Campaign in Support of Angela Mansfield and Scott Keller for Indianapolis City-County Council 2Health News:Tobacco-Free Kids Indiana Action Fund Launches Campaign in Support of Angela Mansfield and Scott Keller for Indianapolis City-County Council 3
... third-generation immunoassay system combines continuous ... processing with a broad testing ... higher volume clinical laboratories to ... tests simultaneously, as well as ...
Architect ci8200 is a flexible solution for your evolving laboratory offering high productivity, one report and one operator interface for both chemistry and immunoassay testing....
... 1 provides a fully automated, ... over 50 assays available worldwide. ... therapeutic drug, serology, anemia and ... on a system designed to ...
The UniCel DxI 800 with its exceptional throughput, proven chemiluminescent technology, assay protocols like Access, Access 2, Synchron LXi 725 and load "on-the-fly" capability simplifies and automat...
Medicine Products: