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Novel Cancer Immunotherapy set to enter Clinical Trials
Date:4/16/2013

LAWRENCEBURG, Ind., April 16, 2013 /PRNewswire/ -- PDS Biotechnology Corporation today presented a summary of the company's preclinical data on its lead cancer immunotherapy PDS0101 at the World Vaccine Congress in Washington DC.  The product is based on the company's ground-breaking and proprietary Versamune™ nanotechnology vaccine platform.  PDS Biotechnology also announced that the company's Investigational New Drug (IND) application had been granted by the FDA allowing PDS0101 to be evaluated in human patients.

PDS0101 is a first-in-class immunotherapy being developed to treat cancers and diseases caused by infection with the human papillomavirus such as cervical cancer, head and neck cancer and cervical intraepithelial neoplasia.  Dr. Frank Bedu-Addo , President and CEO presented the highly promising preclinical efficacy and safety data demonstrating eradication of the tumors without any of the safety drawbacks typical of the current immunotherapy technologies.  PDS0101 is designed to prime the immune system to recruit cells of the body's own immune system to specifically recognize, target and kill the cancer cells.  PDS0101 is also designed to reduce the population of certain immune suppressive cells which prevent our immune systems from detecting and attacking the cancer cells.  "Should the preclinical results be replicated in the clinical setting, this will be a giant leap forward in the development of safe and effective cancer therapies," said Frank Bedu-Addo .

Versamune™ is a nanotechnology-based immune modulating technology which acts by a novel mechanism to prime and activate the immune system to recognize specific diseased cells and disease causing agents.   The technology is unique in its multiple-mode-of-action enabling simple and effective disease-targeting vaccines and immunotherapies to be developed.

About PDS Biotechnology Corporation

PDS Biotechnology is a privately held biotechnology company developing vaccines and immunotherapies based on the company's proprietary Versamune platform.  In addition to PDS0101, the company is also currently developing a potentially game-changing influenza vaccine which in preclinical studies has demonstrated significantly improved speed in which protection against the disease is developed.  In preclinical studies, the strength of the protective immune response was also significantly increased even at lower vaccine doses when compared to the current US licensed flu vaccine.  In June of 2012 PDS granted an exclusive license to Merck KGaA, Darmstadt, Germany for use of Versamune in 2 specific cancer vaccines.  PDS Biotechnology Corporation is headquartered in Lawrenceburg, IN.  Additional information about the company and technology may be found online at http://www.pdsbiotech.com.


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SOURCE PDS Biotechnology Corporation
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