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Novavax Announces Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program
Date:8/26/2008

avax has collaborated with GE Healthcare, a unit of General Electric Company (NYSE: GE), to develop processes using disposable systems as its manufacturing approach. This manufacturing approach permits rapid commissioning at a fraction of the cost of traditional, egg-based manufacturing facilities. The VLP vaccine may be an effective and affordable component of a pandemic solution for countries that do not currently have in-border pandemic vaccine production.

"This data milestone marks good progress in the viability of Novavax's vaccine which, combined with GE Healthcare's ready-to-use bioprocessing technologies, signals the promise of a solution to problems countries face in preparing for the inevitability of pandemic influenza," said Peter Ehrenheim, President and CEO, Life Sciences, GE Healthcare.

"In the face of a global health threat, innovations are required that can deliver safe and effective vaccines quickly and reliably," said Robert B. Belshe, M.D., Dianna and J. Joseph Adorjan Endowed Professor of Infectious Diseases and Immunology at the Saint Louis University School of Medicine, who served on the Data and Safety Monitoring Board for the study. "Two doses of this novel vaccine -- which is designed to prevent bird flu -- gave strong immune responses. The data are encouraging that this new vaccine approach can help prevent pandemic influenza."

Support for VLP Seasonal Influenza Vaccine Candidate

These data are also supportive for moving forward with development of another Novavax vaccine candidate: against seasonal influenza. Seasonal influenza causes over 500,000 deaths worldwide and over 36,000 deaths in the U.S. each year, most of which occur in adults 65 years of age and older, a population in which curren
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SOURCE Novavax, Inc.
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