Navigation Links
Novartis Enters Into Agreement for Exclusive US and Canadian Rights to Fanapt(TM), an FDA-Approved Oral Therapy for Schizophrenia
Date:10/12/2009

00 million for the exclusive rights to commercialize the oral tablet, which is already approved in the US, in the territory of the US and Canada, as well as to develop and commercialize a depot formulation of Fanapt for patients in this territory. Vanda will be eligible for additional payments upon achieving defined development and commercial milestones and will also receive sales royalties. Vanda will retain rights to develop and commercialize Fanapt outside the territory of US and Canada, but Novartis has the option to enter into discussions with Vanda to co-commercialize Fanapt or receive sales royalties outside this territory. The consummation of the transaction is subject to the receipt of customary regulatory approvals, which are expected by the end of 2009.

Important Safety Information

Fanapt is indicated for the acute treatment of schizophrenia in adults.

Increased Mortality: Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death compared to placebo. Fanapt is not approved for the treatment of patients with dementia-related psychosis.

QT Prolongation: In an open-label QTc study in patients with schizophrenia or schizoaffective disorder (N=160), Fanapt was associated with QTc prolongation of 9 msec at an iloperidone dose of 12 mg twice daily. This affect was augmented by the presence of CYP450, 2D6 or 3A4 metabolic inhibition. The use of Fanapt should be avoided in combination with other drugs that are known to prolong QTc. Caution is warranted when prescribing Fanapt with drugs that inhibit Fanapt metabolism.

Neuroleptic Malignant Syndrome (NMS):A potentially fatal symptom complex, has been reported in association with administration of antipsychotic drugs. Clinical manifestations include hyperpyrexia, muscle rigidity, altered mental sta
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Results In The New England Journal Of Medicine Confirm Novartis Drug Femara(R) Is Superior To Tamoxifen After Breast Cancer Surgery
2. US FDA Approves Extavia(R) - the First in a New Portfolio of Planned MS Therapies from Novartis to Help Patients with this Devastating Disease
3. Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative Diabetes Drug Discovery and Development Partnership
4. Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
5. More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
6. Video: Novartis Vaccines and PTA Battle Flu: Public Health Vaccination Initiative Urges Families Lets Fight Flu Together!
7. Emisphere Announces Recruitment of Novartis Phase III Study for Oral Osteoporosis Treatment
8. Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting
9. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
10. Orion Genomics Enters Discovery Collaboration and License Agreement to Advance Personalized Diagnostics
11. Elbit Imaging Ltd. Announces Sale of Plaza Centers Shares
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014 /CNW/ - Bedrocan Cannabis Corp., previously Bedrocan ... to its Board of Directors, enhancing executive oversight ... company, a leading licensed producer of medicinal cannabis ... has 13 years, experience in producing and supplying ... including Canada. As previously announced ...
(Date:8/21/2014)... Aug. 21, 2014  SI-BONE, Inc. ( San ... pioneered the use of the iFuse Implant System, ® ... fusion of the sacroiliac (SI) joint, announced that Priority ... to its Lumbar Fusion Medical Policy No. 91590-R4 providing ... The policy states that the fusion procedure, which employs ...
(Date:8/20/2014)... Aug. 20, 2014 Northstar Global Business ... after months of hard work from many talented ... Snorenz formulation and package design.  The new formulation ... back into the product due to overwhelming evidence ... effects.  Snorenz Nighttime will also include these vitamins, ...
Breaking Medicine Technology:Senior Life Sciences Executives Join Bedrocan as Independent Directors 2Senior Life Sciences Executives Join Bedrocan as Independent Directors 3SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 2SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 3Northstar completes the first phase of its new retail strategy and prepares to ship reformulated Snorenz with all new packaging 2
... China Medical Technologies, Inc. (the "Company") (Nasdaq: ... diagnostic ("IVD") company, today announced that the Company ... improve its balance sheet. The plan may include, ... of the Company,s convertible notes maturing in August ...
... one of every 150 two-year-olds visits an emergency department ... most often after finding and eating or drinking medicines ... safe medication storage and what to do in case ... Healthcare Products Association Education Foundation and a coalition ...
Cached Medicine Technology:China Medical Technologies Intends to Implement Debt Restructuring 2Many Young Children Overdosing From Medicines at Home 2Many Young Children Overdosing From Medicines at Home 3
(Date:8/22/2014)... The rising numbers of teenage substance ... the years, countless lives have been lost due to adolescent ... the community a new helpline was established to provide a ... Ohio who are seeking to overcome their chemical dependency issues. ... (300) 400-2616, parents and their teens can speak immediately to ...
(Date:8/22/2014)... Aid in Recovery, a full service drug and ... recent bill introduced in the Philippines House ... and retired police general. In House Bill 4451, Pagdilao ... than imprisonment. Aid in Recovery points to this bill ... drug addiction epidemic. , The bill, introduced this summer, ...
(Date:8/22/2014)... Lexington, North Carolina (PRWEB) August 22, 2014 ... United Church Homes and Services (UCHS ), recently ... frail and at risk seniors with limited resources in ... open floor plan, fully operational kitchen, individually controlled heating ... The HUD Section 202 supportive housing community, consists of ...
(Date:8/21/2014)... Os-Monitor.com, an outstanding online supplier of useful ... software collection ( http://www.os-monitor.com ). In addition to ... these high end items are offered with greatly ... improving productivity, the employers pay more attention to ... and network monitoring software products are becoming more ...
(Date:8/21/2014)... (PRWEB) August 22, 2014 The natural loss ... fine lines, wrinkles and sagging of skin. Using products ... "By age 40, the body has lost about 15% of ... about 45%," says Kathy Heshelow, founder of Sublime Beauty®. ... of it - well, we know what happens." , Collagen ...
Breaking Medicine News(10 mins):Health News:Troubled Teens in Akron, OH Can Receive Assistance from New Helpline for Addiction Recovery 2Health News:Proposed Legislature in the Philippines Highlights the Need for Rehabilitation, Not Incarceration, for Drug Users, Says Aid in Recovery 2Health News:Proposed Legislature in the Philippines Highlights the Need for Rehabilitation, Not Incarceration, for Drug Users, Says Aid in Recovery 3Health News:United Church Homes and Services Announce New Affordable Housing Community for Seniors 2Health News:New Employee Monitoring Software Collection Unveiled By Os-Monitor.com 2Health News:4 Skincare Products That Boost and Nurture Collagen on Sale at Sublime Beauty® 2Health News:4 Skincare Products That Boost and Nurture Collagen on Sale at Sublime Beauty® 3
... of men as an erectile dysfunction (ED) medication for ... rates of// patient and partner satisfaction. However, Researchers have ... ,Recent reports have appeared about some individuals ... narcotics such as methamphetamines. These reports further note that ...
... the leaders of the world system are falling short of pennies ... poorest of the poor communities marred by diabetes from snow diving ... the form of appropriate care when compared to those who suffer ... ,Statistics reveal that Over two million people are diagnosed ...
... Freddie and Thomas Greenstreet were born two weeks ago ... genetic haplotyping that screens for genetic// diseases. ... cystic fibrosis (CF). Pre-implantation genetic haplotyping looks for a ... disease, Huntington's disease, Duchenne muscular dystrophy and spinal muscular ...
... (ACS) has planned to celebrate the 30th anniversary of ... objective of the Great American Smokeout over the past ... dangers of tobacco use as well as the challenges ... want to quit are urged to call the American ...
... released in the state of Pennsylvania, U.S,reveals that there were ... 2005.// ,The report the first of ... various hospitals spread all over the state released in Pennsylvania ... hospital acquired infections when admitted there for some treatment or ...
... platelet-depleting autoimmune disease in a whole new way, ... thrombocytopenic purpura (ITP) once again// produce healthy amounts ... ,That's the conclusion of a new, ... professor of pediatrics at Weill Cornell Medical College, ...
Cached Medicine News:Health News:HIV and Erectile Medications - No Link Found 2Health News:Poor diabetics: bitter times and worse times with no sweet respite 2Health News:First Embryos in UK Screened for Disease 2Health News:Hospital infections gaining ground in Pennsylvania hospitals 2Health News:Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura 2Health News:Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura 3
... and Quality Assurance (for Waived and PPM ... clinics and small hospitals maintain laboratory excellence. ... patient lab results and assist labs in ... to earn 12 P.A.C.E. Contact hours per ...
An enzyme linked immunosorbent assay (ELISA) for the detection and quantitationof RF IgG isotype in human serum of patients with rheumatoid arthritis....
An enzyme linked immunoassay (ELISA) for the detection and semiquantitationof IgG and IgM antibodies to 2-GP1, as an aid in assessingthe risk of thrombosis in patients with Systemic Lupus Erythematos...
An enzyme linked immunoassay (ELISA) for the detection and semiquantitation of IgG, IgA or IgM anticardiolipin antibodies, as an aid in assessing the risk of thrombosis in individuals with Systemic L...
Medicine Products: