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Novartis Drug SOM230 is First Medical Therapy to Show Efficacy in a Phase III Trial in Cushing's Disease, a Debilitating Hormonal Disorder
Date:9/21/2010

leading positions in each of these areas. In 2009, the Group's continuing operations achieved net sales of USD 44.3 billion, while approximately USD 7.5 billion was invested in R&D activities throughout the Group. Headquartered in Basel, Switzerland, Novartis Group companies employ approximately 102,000 full-time-equivalent associates and operate in more than 140 countries around the world. For more information, please visit http://www.us.novartis.com.

References

  1. Colao, A. Pasireotide (SOM230) provides clinical benefit in patients with Cushing's disease: results from a large, 12-month, randomized-dose, double-blind, Phase III study. Abstract OC1.7. European Neuroendocrine Association (ENEA) 14th Congress
  2. National Endocrine and Metabolic Diseases Information Service. Cushing's syndrome. Available at: http://endocrine.niddk.nih.gov/pubs/cushings/Cushings_Syndrome_FS.pdf. Accessed August 2010
  3. MedlinePlus. Cushing's disease. Available at: http://www.nlm.nih.gov/medlineplus. Accessed August 2010
  4. Colao, A., et al. Persistence of increased cardiovascular risk in patients with Cushing's disease after five years of successful cure. J Clin Endocrin Metabol. 1999: 84(8); 2664-2672
  5. Pituitary Network Association. Cushing's syndrome. Available at: http://www.pituitary.org. Accessed August 2010
  6. PASPORT: A global clinical research program to advance patient care. Available at: http://www.pasporttrials.com/index.jsp. Accessed August 2010
  7. US Food and Drug Administration. Drugs@FDA. Available at: http://www.accessdata.fda.gov/scripts/cder/drugsatfd
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