Navigation Links
Novartis Drug SOM230 is First Medical Therapy to Show Efficacy in a Phase III Trial in Cushing's Disease, a Debilitating Hormonal Disorder
Date:9/21/2010

230 targets multiple subtypes of the receptor for somatostatin (sst), a hormone that controls the pituitary gland. Its highest affinity is to sst5, a receptor subtype frequently expressed by the pituitary tumors associated with Cushing's disease. Currently approved somatostatin analogs preferentially bind to sst2 and are not effective in Cushing's disease(6).

SOM230 is currently being studied as a twice-daily sc injection, as well as a long-acting release (LAR) once-monthly intramuscular injection for the treatment of multiple disease types, including Cushing's disease, carcinoid syndrome and acromegaly(10).

Because it is an investigational compound, the safety and efficacy profile of SOM230 has not yet been established. Access to this investigational compound is available only through carefully controlled and monitored clinical trials. These trials are designed to better understand the potential benefits and risks of the compound. There is no guarantee that SOM230 will become commercially available(6).

Information about Novartis clinical trials for SOM230 can be obtained by healthcare professionals at www.pasporttrials.com.

DisclaimerThe foregoing release contains forward-looking statements that can be identified by terminology such as "will," "planned," "potential," or similar expressions, or by express or implied discussions regarding regulatory submissions or approvals for SOM230, or the timing of such submissions or approvals, or regarding potential future revenues from SOM230. You should not place undue reliance on these statements. Such forward-looking statements reflect the current views of management regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results with SOM230 to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guar
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
2. Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting
3. Emisphere Announces Recruitment of Novartis Phase III Study for Oral Osteoporosis Treatment
4. Video: Novartis Vaccines and PTA Battle Flu: Public Health Vaccination Initiative Urges Families Lets Fight Flu Together!
5. More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
6. Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
7. Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative Diabetes Drug Discovery and Development Partnership
8. US FDA Approves Extavia(R) - the First in a New Portfolio of Planned MS Therapies from Novartis to Help Patients with this Devastating Disease
9. Results In The New England Journal Of Medicine Confirm Novartis Drug Femara(R) Is Superior To Tamoxifen After Breast Cancer Surgery
10. Novartis Enters Into Agreement for Exclusive US and Canadian Rights to Fanapt(TM), an FDA-Approved Oral Therapy for Schizophrenia
11. Novartis Pharmaceuticals Corporation Prevails in Medicaid Pricing Case Before Alabama Supreme Court
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... 2014 Australian biomarker discovery company Minomic International ... its MiStat™ prostate cancer screening test, planning to achieve ... completion. Minomic,s proprietary MiStat™ technology is a ... proprietary biomarker known as the MIL-38 antigen. This biomarker ... Researchers at 11 leading urology centres ...
(Date:9/18/2014)... YORK , Sept. 18, 2014 Relmada ... therapies for the treatment of chronic pain, announced today ... to the position of  Senior Director of Clinical ... Research, Mr. James has established and led successful global ... Europe , to facilitate the clinical development of ...
(Date:9/18/2014)... , Sept. 18, 2014  Spring Bank ... therapeutics for the treatment of RNA viruses, today ... of Health (NIH) for animal testing of the ... pathogens, classified as "Special Pathogens," against which currently ... derived from Spring Bank,s proprietary Small ...
Breaking Medicine Technology:Minomic Launches US Pilot Study of MiStat(TM) Novel Prostate Cancer Screening Technology 2Relmada Therapeutics, Inc. Appoints Christopher W. James As Senior Director of Clinical Development 2Spring Bank Pharmaceuticals Announces NIH Collaboration for Testing of SB 9200 Against Multiple Viral Pathogens 2
... Feb. 16, 2012 Millstone Medical Outsourcing announced today ... CA, and Warsaw, IN.  With new offices positioned in ... will be able to provide customer-specific program development as ... Senior Vice President, will run the San Diego office, ...
... Inc. (PSI), a leading pharmaceutical CRO, announced today that ... oral formulation efforts.  According to Mark Mitchnick, the company,s ... technologies applicable across many dosage forms and drug types.  ... on small molecules of which about 80% fall into ...
Cached Medicine Technology:Millstone Medical Outsourcing Opens Sales Offices in CA, IN 2Particle Sciences Hires Robert Gwozdz to Head Oral Formulation 2
(Date:9/18/2014)... the popular online supplier of funny figurines, has added a ... line. Moreover, all the company’s products are now offered with ... special offer before September 29, 2014. Customers who place bulk ... bobblehead doll ). , “We are pleased to ... make our interesting items available to all the global customers. ...
(Date:9/18/2014)... Hills, CA (PRWEB) September 18, 2014 ... camp, is the fastest-selling fitness business in the country and ... work out, has continued to grow enormously in 2014. ... Camp World Conference, is taking place in Costa Mesa, CA ... one of the biggest conferences yet. Founder Bedros Keuilian, who ...
(Date:9/18/2014)... A positive outlook on life can go ... This year, at the Weekend for Women Conference in Los ... radio talk show host Mother Love will be speaking on ... , The always-funny Jo Anne Hart, aka Mother Love, has ... her widely acclaimed talk show on LATalkRadio.com, which airs weekdays ...
(Date:9/18/2014)... September 18, 2014 How much is ... one of the factors contributing to the obesity epidemic ... a single serving and how to manage portion size ... presentation Oct. 3 at Humility House, 755 Ohltown Road, ... will lead the informational discussion and answer questions from ...
(Date:9/18/2014)... It is true that a business-oriented ... a successful brand or business online. Best Cheap ... compared plenty of professional web hosting suppliers and ... iPage are the best VPS hosting suppliers in ... hosting. All-sized businesses or enterprises can find the ...
Breaking Medicine News(10 mins):Health News:Discounted Custom Bobbleheads Online For Sale At WowBobble.com 2Health News:With Fit Body Boot Camp World Conference Nearing, Founder Explains the Fitness Boot Camp Franchise’s Success 2Health News:With Fit Body Boot Camp World Conference Nearing, Founder Explains the Fitness Boot Camp Franchise’s Success 3Health News:DiabetesSisters Showcases Radio Talk Show Host Mother Love at Weekend for Women Conference in Los Angeles 2Health News:HMHP Workshop Addresses Portion Control 2Health News:Best Cheap Hosting USA: GreenGeeks, Arvixe And iPage Are The Best Hosting Suppliers In 2014 2
... last year when he gave the slip to authorities after being ... ailing son. ,He has now been captured, along with ... in Puerto Vallarta on Mexico's Pacific coast, said Deputy U.S. Marshal ... by a federal judge in January 2006 so he could complete ...
... burst into the open in Paris, Dr. Brian Halevie-Goldman, ... months by the// Californian state authorities. ,Dr.Goldman ... Laboratory Co-Operative that allegedly provided steroids to top athletes. ... years' probation and ordered to undergo a psychiatric evaluation ...
... abalone are paying with their lives. Four people perished in ... used in sushi// and a variety of other Asian dishes ... market. ,Abalone are a special type of shellfish ... delicacy in certain parts of Latin America (especially Chile), South ...
... consumer court in Himachal Pradesh has fined the soft drink ... a consumer five years ago//. The complaint was lodged after ... ,The Himachal Pradesh Consumer Redressal Commission here Tuesday asked ... in 2002 by a consumer in Dharamsala, 280 km from ...
... not only protects memories from outside interferences, but also ... looked at memory recall with and without interference (competing ... 30 took part in the study. All had normal, ... Participants were divided evenly into four groups—a wake group ...
... of the body’s genetic repair system may cause Huntington’s ... by destroying their nervous system. Until now, no one ... ,"We showed that when single-strand breaks in ... gene continued to add extra replacement segments," explains Cynthia ...
Cached Medicine News:Health News:Fugitive Who Ditched His Ailing Son Arrested After a Year 2Health News:US Psychiatrist Suspended from Practicing Medicine for Involvement in Doping Scam 2Health News:US Psychiatrist Suspended from Practicing Medicine for Involvement in Doping Scam 3Health News:Hunt for Sea Delicacy Taking a Toll in California 2Health News:Hunt for Sea Delicacy Taking a Toll in California 3Health News:Sleep Makes Your Memory Strong 2Health News:Researchers Discovers DNA Repair as Key to Huntington's Disease 2
Hydrophobic PE filter without self-sealing additives, permits sample recovery after accidental over-pipetting. All filters are sterile (to USP, DAB, Ph.Eur. standards) and PCR clean (free from human ...
Ideal for use with low volume samples on the Biomek robotic pipetting systems, the ART 20R provides guaranteed protection for your expensive workstation....
... eliminate false signals and contamination caused ... Promega Barrier Tips offer performance and ... acids (PCR(a)), radioactive isotopes, tissue culture ... specimens. , ,Promega Barrier Tips are ...
... 0.5l - 10l Eppendorf Barrier Tips. Designed to ... reduces the amount of DNA and proteins bound ... advertised as low retention, which means the focus ... tip. However, AvantGard also focuses on low binding ...
Medicine Products: