Navigation Links
Novagali Pharma Successfully Enrolls First Patient in U.S. Phase I Clinical Study with CORTIJECT(R) for Diabetic Macular Edema
Date:4/24/2008

EVRY, France, April 24 /PRNewswire/ -- Novagali Pharma, an emerging ophthalmic pharmaceutical company today announced that it has successfully injected the first patient in a Phase I clinical trial using CORTIJECT(R), an ophthalmic injectable emulsion based on EYEJECT(R) technology platform containing a corticosteroid prodrug for the treatment of Diabetic Macular Edema (DME). This trial, which will enrol a total of 15 patients, is designed to evaluate the safety and to observe the efficacy trend of CORTIJECT(R). The patients will be monitored for a period of twelve months following injection. Company's Investigational New Drug Application (IND) to conduct this Phase I clinical trial has been granted by the U.S. Food and Drug Administration (FDA) in January 2008 (cf. Novagali Pharma Press Release issued on January 18th, 2008).

"This first injection in patient is a crucial step toward the clinical development of our state-of-the-art technology for the posterior segment of the eye that can be used to develop new treatments for retinopathies" said Jerome Martinez, Pharm.D., Novagali Pharma Chief Executive Officer. "Thanks to EYEJECT(R) technology, CORTIJECT(R) is a major move with the optimized use of corticosteroids for the back of the eye expected to combine ease of use, sustained release and ocular safety. Administering this emulsion through a single injection can offer real medical value to both physicians and patients."

Investigators for this open-label, dose-escalation study will treat patients suffering from DME with a single intravitreal injection (inside the eye) of CORTIJECT(R) formulation. The trial will include 3 treatment arms with patients receiving one of three doses of Novagali Corticosteroid prodrug. Each administration of CORTIJECT(R) will provide the patient with exposure to the compound for approximately nine months.

About Novagali Pharma : http://www.novagali.com


'/>"/>

SOURCE Novagali Pharma
Copyright©2008 PR Newswire.
All rights reserved

1

GOOD

Page: 1 2

Related medicine technology :

1. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
2. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
3. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
4. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
5. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
6. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
7. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
8. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
9. Par Pharmaceutical Begins Shipment of Additional Dosage Strength of Generic TOPROL-XL(R)
10. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
11. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2009)... , KNOXVILLE, Tenn., Dec. 2 ...m ), a division of the nation,s largest provider o...t has signed two contracts to provide teleradiolog...linois. ,, An agreement signed with UpState Car... allow TeamHealth Teleradiology to provide service...
(Date:12/2/2009)... , PHILADELPHIA, Pennsylvania, December 2 ...DAQ: SHPGY ), the global specialty biopharmaceuti...igation with Teva,Pharmaceuticals USA, Inc. ("Teva...neric version of ADDERALL XR. Shire has been suppl...e April 1, 2009. Shire,s ability to supply,the pro...
(Date:12/2/2009)... , ROCKVILLE, Md., Dec. 2 /PRNewswire-FirstCall... favorable initial results from the first stage of... safety and immunogenicity of the company,s 2009 H...accine. Novavax is conducting this study in colla...port registration of the vaccine in Mexico and pot...
Breaking Medicine Technology:TeamHealth Teleradiology Announces New Contracts in South Carolina and Illinois 2Shire and Teva Settle Litigation Concerning Supply of ADDERALL XR Authorized Generic 2NOVAVAX Reports Positive Clinical Results from Pivotal Study of H1N1 Influenza Vaccine in Mexico 2NOVAVAX Reports Positive Clinical Results from Pivotal Study of H1N1 Influenza Vaccine in Mexico 3NOVAVAX Reports Positive Clinical Results from Pivotal Study of H1N1 Influenza Vaccine in Mexico 4Aegis Living Chosen as Best Retirement Facility in 2009 Best of 425 magazine 55950 1Aegis Living Chosen as Best Retirement Facility in 2009 Best of 425 magazine 55950 2Video 3A Renowned Health Expert Dra Aliza Teams Up With Baby Looney Tunes To Promote Healthy Happy Babies 55945 1Video 3A Renowned Health Expert Dra Aliza Teams Up With Baby Looney Tunes To Promote Healthy Happy Babies 55945 2Video 3A Renowned Health Expert Dra Aliza Teams Up With Baby Looney Tunes To Promote Healthy Happy Babies 55945 3Video 3A Renowned Health Expert Dra Aliza Teams Up With Baby Looney Tunes To Promote Healthy Happy Babies 55945 4United Therapeutics Corporation Announces Stock Split To Be Effected as a Stock Dividend 13786 1United Therapeutics Corporation Announces Stock Split To Be Effected as a Stock Dividend 13786 2
... and Disease-Free Survival -, WAYNE, N.J., June 5...noma patients demonstrated that a majority of pati...ed disease-free and/or overall,survival. These fin...cancer,setting, were released at the 44th annual m...y (ASCO)., Results from the Phase II study (ASCO ...
...t International Conference on Malignant L...y, BETHESDA, Md., June 5 Micromet, Inc. (Nasdaq:...el, proprietary antibodies,for the treatment of ca...presented an update of an ongoing phase 1 clinical...3/MEDI-538) at the 10th International Conference,o...
Other Medicine Technology:Study Supports Possible Use of Leukine(R) as a Potential Adjuvant Therapy for High-Risk Melanoma Patients 2Study Supports Possible Use of Leukine(R) as a Potential Adjuvant Therapy for High-Risk Melanoma Patients 3Study Supports Possible Use of Leukine(R) as a Potential Adjuvant Therapy for High-Risk Melanoma Patients 4Study Supports Possible Use of Leukine(R) as a Potential Adjuvant Therapy for High-Risk Melanoma Patients 5Micromet's BiTE Antibody Blinatumomab (MT103/MEDI-538) Demonstrates Durable Responses in Patients with Relapsed Non-Hodgkin's Lymphoma 2Micromet's BiTE Antibody Blinatumomab (MT103/MEDI-538) Demonstrates Durable Responses in Patients with Relapsed Non-Hodgkin's Lymphoma 3Micromet's BiTE Antibody Blinatumomab (MT103/MEDI-538) Demonstrates Durable Responses in Patients with Relapsed Non-Hodgkin's Lymphoma 4Micromet's BiTE Antibody Blinatumomab (MT103/MEDI-538) Demonstrates Durable Responses in Patients with Relapsed Non-Hodgkin's Lymphoma 5
(Date:12/2/2009)... many more to come, NIH director says, , ...n stem cell lines have been added to the pool that...and many more such lines will soon be made availab..., These are the first additional embryonic stem ce...National Institutes of Health (NIH) since Presiden...
(Date:12/2/2009)...Directors Represent Diverse Healthcare Stakeholder...re/ -- The membership of the National Quality Foru...irectors and reappointed four current Board member... healthcare stakeholders, including consumers, pro...ommunity healthcare. ,, The newly elected Boar...
(Date:12/2/2009)...Dec. 2 TeamHealth ( www.teamhealth...ith the acquisition of Naples-based Emergency Phys...EPN has held an exclusive contract with NCH Health...he Downtown Naples Hospital, North Naples Hospital...es the staffing for two stand-alone urgent care cl...
(Date:12/2/2009)...duced movement therapy (CIMT) is a potentially eff...plegic cerebral palsy, but more research is needed...n the November issue of Physical Therapy (PTJ), ...erapy Association (APTA). The review, which analyz...s, concluded that further research should focus on...
(Date:12/2/2009)...nday, more than 900 runners and walkers from Las V...line at the Rock ‘n’ Roll Las Vegas Ha....2 million for the Crohn,s & Colitis Foundatio... Challenge (www.ccteamchallenge). As the official ...arch, education, and support initiatives to benefi...
Breaking Medicine News(10 mins):Health News:U.S. Approves New Stem Cell Lines for Publicly Funded Research 2Health News:U.S. Approves New Stem Cell Lines for Publicly Funded Research 3Health News:National Quality Forum Members Elect Nine Directors to Board 2Health News:National Quality Forum Members Elect Nine Directors to Board 3Health News:TeamHealth Acquires Emergency Physicians of Naples, LLC 2Health News:Report shows CIMT may improve arm use in children with hemiplegic cerebral palsy 2Health News:Raising Millions for Team Challenge through Rock ‘n' Roll Las Vegas Half Marathon Program Brings Hundreds From Across the Country to Raise Funds for Crohn's & Colitis 2Health News:Raising Millions for Team Challenge through Rock ‘n' Roll Las Vegas Half Marathon Program Brings Hundreds From Across the Country to Raise Funds for Crohn's & Colitis 3Health News:Raising Millions for Team Challenge through Rock ‘n' Roll Las Vegas Half Marathon Program Brings Hundreds From Across the Country to Raise Funds for Crohn's & Colitis 4
.... (OTC Bulletin Board: FGHH) today announced that ...e date for the Company,s annual stockholder,s,meet...ater date., About Flagship Global Health, Flagsh...at home or traveling., Flagship is focused on pro...
...nstitute report that full-body PET/CT scanning det...ients with Li-Fraumeni syndrome (LFS), a rare gene...ave been recommended. , The results suggest that ...urnal of the American Medical Association. But the...
...are, (http://www.VieHealthcare.com ) announced tod...C (http://www.CJPS-Enterprises.com ) to expand it...regional office in Troy, Michigan., The new offic...hcare, a nationally recognized organization, speci...
...s cited in new research , , TUESDAY, March...art disease, bone health and post-traumatic stress...etics is poised to revolutionize medicine, said sc...ses than others -- and how they might be helped. ...
... one of only a few centers in Canada that perform ...cedure developed in the late 1980s that expands th... done a year in Alberta, 10 of those being living-...le duct anatomy. Thanks to a review paper done at ...
...und the World, Supports,Public Health Abroad, BAL...g thousands of scientific articles by African and ... 400,000 resources, announced the,Johns Hopkins Bl...d One Source,( http://www.infoforhealth.org/onesou...
Other Medicine News:Health News:Scans spot hidden tumors in rare cancer syndrome 2Health News:Scans spot hidden tumors in rare cancer syndrome 3Health News:VIE Healthcare Expands Its Operations in the Midwest, and Obtains First Local Client 2Health News:Genetic Medicine Making Inroads Against Disease 2Health News:Genetic Medicine Making Inroads Against Disease 3Health News:Resources Top 400,000 in Hopkins International Information Service 2
...ial growth system, combines orbital shaking, oxyge...or bacterial growth. It is designed for easy integ... Extractor. The uniquely engineered HT-MegaGrowTM ...hakers. Plate-holding cassettes allow for high pla...
Innova 4300 Floor Model Incubator Shaker, Large Capacity Chest Style
Innova 4330 Floor Model Incubator Shaker, Large Capacity Chest Style with Refrigeration
Innova 44R Large-Capacity, Floor-Stackable Incubator Shaker with Refrigeration
Medicine Products: