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Nova Southeastern University Researchers Receive $4.1 Million Grant from Department of Defense to Investigate Gulf War Illness
Date:11/19/2013

r understanding of Gulf War Illness through discovery of biomarkers to more accurately diagnose and treat this syndrome," said Col. Wanda Salzer, M.D., director of Congressionally Directed Medical Research Programs (CDMRP). "Working as an integrated team, the scientists, clinicians, and veterans at these accomplished organizations will be able to establish synergy and collectively develop research strategies which may unlock the pathways leading to the regulatory dysfunction in Gulf War Illness."

Col. Salzer added that the long-term goal of the CDMRP GWI research program is the investment in a lasting infrastructure of relationships among the participating organizations fostering continuing research collaborations and future clinical trials focused on GWI.

GWI is a medical condition that affects veterans and civilians who were exposed to a number of dangers, including chemical weapons, during the 1991 Gulf War. Symptoms can include chronic headaches, widespread pain, cognitive difficulties, debilitating fatigue, gastrointestinal problems, respiratory symptoms, and other abnormalities that are not explained by established medical diagnoses or standard laboratory tests. At least a quarter of the nearly 700,000 soldiers who fought in the Gulf War suffer from GWI, according to the U.S. Department of Veterans Affairs' Research Advisory Committee on Gulf War Veterans' Illnesses.

"Our goal is to develop a better understanding of GWI and understand specific causes so we can find treatments to address these causes, rather than focus on the symptoms," said Klimas. "This consortium will integrate our clinical understanding of the disease process with basic research efforts using a novel mathematical model."

It has been established that GWI is caused by a disruption in normal cell signaling that results in disabling symptoms including fainting, low blood pressure, fatigue, and pain. This is primarily due to disruptions in
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