Navigation Links
Not Only Lipids and Inflammation: Insight Into a New Cause of Heart Attack and Other Vascular Disease
Date:1/6/2008

REYKJAVIK, Iceland, Jan. 6 /PRNewswire/ -- deCODE scientists today report that the genetic variant on chromosome 9p21 that the company has linked to increased risk of heart attack is also associated with up to 70% increase in risk of abdominal aortic aneurysm (AAA) and intracranial aneurysm (IA). This is the first common genetic variant ever found to associate with either condition. The paper, entitled 'The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm,' is published today in the online edition of Nature Genetics, at http://www.nature.com/ng.

AAA and IA are the most common aneurysms - balloon-like protrusions on arteries in the abdomen and head, respectively - and are potentially lethal if they are left untreated and burst. "Today's findings enhance the importance of our 9p21 variant when it comes to risk of cardiovascular disease, and suggest that it confers this risk by affecting how artery walls respond to other risk factors such as atherosclerotic plaque and inflammation," said Kari Stefansson, CEO of deCODE. "As we bring these findings into our cardiovascular therapeutics program, we are also incorporating them into our deCODE MI diagnostic test and our deCODEme(TM) personal genome analysis service. With today's discovery and others we expect to announce in the weeks and months ahead, we underscore our global leadership in human genetics and our commitment to convert this leadership into products and the products into profit for our shareholders."

Six months ago, deCODE reported that this SNP confers significantly increased risk of coronary artery disease (CAD) and accounts for roughly one- third of early-onset heart attacks. This discovery has now been replicated in studies of ten populations. The study published today was aimed in part at investigating how this risk is conferred. To do so, the deCODE team, - enli
'/>"/>

SOURCE deCODE genetics Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. PDHI Launches ConXus Rewards, Announces Partnership With Hallmark Insights to Support Incentive-Driven Wellness Programs
2. Seriously Low Vaccination Rates Cause Experts to Call for Increased Immunization Before Influenza Season Peaks
3. Influenza is Leading Cause of Vaccine-Preventable Deaths for Kids; Despite CDC Recommendations, Moms Still Dont Vaccinate
4. St. Jude Identifies the Specific Cell That Causes Eye Cancer, Disproving Long-Held Theory
5. UNICEF Partners With Causes on Facebook to Launch Charity Gift Feature
6. Many Heart Attack Patients Dont Get Best Emergency Treatment
7. The Heart, Diabetes, And Weight Loss Centers of New York Introduce the New Science of Metabolic Diagnosis and Weight Management
8. American Heart Association Comment Saving Lives in Type 2 Diabetics: Could It Be as Easy as Lowering Blood Pressure?
9. Terumo Heart to Announce Results of European Clinical Trial of DuraHeart(TM) LVAS at European Association of Cardiothoracic Surgeons Meeting in September
10. WorldHeart Announces Further Milestone in Miniaturized Assist Pump Development
11. CellCyte Genetics Corp. Enters Collaborative Research Agreement With Cleveland Clinic Foundation to Qualify Stem Cell Delivery in Damaged Heart Tissue
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... 2, 2014   Santa Clara dentist , Dr. ... promotion for Invisalign. Invisalign is an orthodontic system that ... is often the orthodontic treatment of choice for older ... of it. For a limited time, patients can try ... from the usual cost. This offer cannot be combined, ...
(Date:9/2/2014)... Spain , September 2, 2014 ... at ESC CONGRESS 2014 provide insight into treatment ... in everyday clinical practice --   ... Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF), ... that stroke prevention strategies for atrial fibrillation (AF) ...
(Date:9/2/2014)... -- Ortho Development® Corporation (ODEV) has received FDA ... addition to its growing hip replacement product line. ... in total hip arthroplasty and hemiarthroplasty procedures. ... Alpine was developed based on the clinically-proven, ... closely with a select team of orthopedic surgeons ...
Breaking Medicine Technology:Santa Clara Cosmetic Dentist, Dr. Alan Frame, is Now Offering a Special on Invisalign 2Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 2Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 3Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 4Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 5Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 6Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 7Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 8Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 9Ortho Development Receives FDA Clearance for Alpine Hip Stem 2
... R.I., June 13, 2011 CVS Caremark Corporation (NYSE: ... executive vice president and chief financial officer of CVS ... the Jeffries 2011 Global Consumer Conference on June 22, ... AM EDT. (Logo: http://photos.prnewswire.com/prnh/20090226/NE75914LOGO ) ...
... Henry Schein, Inc., (NASDAQ: HSIC ), the ... practitioners, announced today that Stanley M. Bergman, Chairman ... the Company,s Executive Vice President and Chief Financial Officer, will ... is taking place at the Four Seasons Hotel in Chicago. ...
Cached Medicine Technology:CVS Caremark to Present at the Jefferies 2011 Global Consumer Conference 2Henry Schein to Present at the William Blair 31st Annual Growth Stock Conference 2
(Date:9/2/2014)... 2, 2014 (HealthDay News) -- Complications are rare ... reconstruction, a new study indicates. However, the ... associated with a slightly higher risk for certain ... included more than 18,000 breast cancer patients who ... mastectomy with breast reconstruction and were followed for ...
(Date:9/2/2014)... return to the emergency department within a few days of ... symptoms and have lost trust in other parts of the ... published online today in Annals of Emergency Medicine ... ). , "When asked why they did not ... symptoms were too severe to wait until their scheduled appointment ...
(Date:9/2/2014)... Sept. 2, 2014 (HealthDay News) -- Two new studies ... suggests that 6-year-olds who were breast-fed have a lower ... bottle-fed infants, while the other finds a similar trend ... the "many benefits of breast-feeding in the immediate newborn ... Hill Hospital in New York City. She was not ...
(Date:9/2/2014)... -- Drinking and marijuana may lead to different types ... Researchers analyzed 2007 to 2011 data gathered from ... they had used alcohol or marijuana at least once. ... with more unsafe driving, damage to relationships with friends ... the influence of alcohol, especially among females. ...
(Date:9/2/2014)... Anti-aging is proving to be ... as anti-wrinkle treatments and products, hair restoration treatments, ... augmentation becoming much sought after worldwide. In a ... firm Transparency Market Research, the global market for ... USD 191.7 billion by 2019, from being worth ...
Breaking Medicine News(10 mins):Health News:Complication Rates Low With Mastectomy, Breast Reconstruction: Study 2Health News:Discharged patients return to the ER because 'better safe than sorry' 2Health News:More Evidence Breast-Feeding Lowers Child's Risk of Infections, Allergies 2Health News:Booze, Pot Bad for Teens in Different Ways, Study Suggests 2Health News:Global Anti-aging Market Research Report 2018 by Transparency Market Research 2Health News:Global Anti-aging Market Research Report 2018 by Transparency Market Research 3
... the same-sex marriage, has said she would prefer to stay ... their marriage ends. ,Recording her statement before civil ... abducted by anyone, adding that their marriage took place with ... be his life partner and he responded to my proposal ...
... and the Institute for the Study of Labour has revealed ... ,In the study of 1000 adults in Germany, the ... of 100 euros today or 150 euros in a year's ... measured the cognitive abilities of the participants, using two different ...
... seen the first-ever signs of a drop in new ... country with the world's second-heaviest AIDS burden. ... HIV prevalence among pregnant women had dropped to 29.1 ... Manto Tshabalala-Msimang told journalists in Pretoria. ,"The ...
... School of Medicine in St. Louis, Missouri, have found ... to treatments for deadliest poisons like Ricin, cholera toxin, ... deadly strains of E. coli bacteria, these toxins travel ... Golgi network and endoplasmic reticulum before interrupting protein synthesis. ...
... Committee on Economic Affairs (CCEA) today gave its approval ... (RNTCP) for five years - - from April ... of Chhattisgarh, Jharkhand and Uttranchal. ,The CCEA also ... project - - Andhra Pradesh, Chandigarh, Haryana, Maharashtra, Punjab ...
... are a group of five large lakes in North America ... largest group of fresh water lakes on Earth. ... levels of toxic chemicals in the lakes are alarmingly high. ... Great Lakes Fish, analyzed the fish advisories published by the ...
Cached Medicine News:Health News:People With Higher IQs are More Patient in Financial Matters 2Health News:Great Lakes Fish in Canada Heavily Polluted 2Health News:Great Lakes Fish in Canada Heavily Polluted 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
The GII titanium anchor with nitinol arcs is used for soft tissue reattachment to bone. The GII's small size, high pull-out strength and wide range of clinical applications make it the anchor used by...
Medicine Products: