Navigation Links
Northwestern Memorial Study Tests Cancer Drug on Scleroderma Patients
Date:3/6/2008

Study Seeks Treatment to Address Skin Hardening Affects of the Devastating Disease

CHICAGO, March 6 /PRNewswire-USNewswire/ -- Physicians at Northwestern Memorial Hospital are studying the effects of an anti-cancer drug to treat patients with scleroderma, a rare, incurable autoimmune rheumatic disease that leads to hardening and tightening of the skin and connective tissues. Scleroderma affects an estimated 300,000 people in the United States and can often attack the lungs, heart, kidneys and intestinal tract, and sometimes lead to death.

The study is the first of its kind to examine if Gleevec, a cancer drug commonly used to treat leukemia, will treat the skin thickness in scleroderma patients by blocking the pathway that causes fibrosis. Patients enrolled in the clinical trial will receive daily oral doses of Gleevec for six months and will be evaluated initially on a weekly basis at Northwestern Memorial, one of only three centers nationwide participating in the study. Others include Johns Hopkins and Boston University Medical Center.

John Varga, MD, rheumatologist at Northwestern Memorial, John and Nancy Hughes Distinguished Professor in Rheumatology at Northwestern University's Feinberg School of Medicine and principal investigator of the study, said this could be a big step forward for people diagnosed with scleroderma. "Based on recent research performed by investigators at the Feinberg School, Gleevec shows potential efficacy in reducing the abnormal skin changes associated with scleroderma."

The exact cause of Scleroderma, a chronic disease most commonly found in women between the ages of 30 and 40, remains unknown. Through continued research, Northwestern Memorial physicians hope to identify treatments to target the disease and improve the quality of life for patients living with Scleroderma.

"We hope that the use of Gleevec for a sustained period of time will decrease the symptoms of skin hardening, and po
'/>"/>

SOURCE Northwestern Memorial Hospital
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Northwestern Offers Clinical Research and Regulatory Administration Graduate Certificate Program
2. Northwestern Memorial Transplant Program Initiates New Study
3. Bertrand Study Finds Significant Value in Breast-Specific Gamma Imaging (BSGI) as an Adjunctive Procedure in Breast Diagnostics
4. Study Finds Starion Instruments Tissue Welding Technology Safe and Effective in Parotidectomy Procedures
5. Thomson Healthcare Cancer Profiler Used in Study
6. Pharmacopeia Initiates Second Phase 2 Hypertension Study with PS433540 (DARA)
7. Genetic Variation Associated with Treatment Response in a Clinical Study of a New Atypical Antipsychotic Fiaptatm (iloperidone)
8. CMC, Moffitt Partner to Study Cancer
9. Pharmacopeia Completes Enrollment in Phase 2 Hypertension Study with PS433540 (DARA)
10. Oral Talactoferrin Alfa Improves Overall Survival in Patients With Refractory Non-Small Cell Lung Cancer: Final Phase 2 Study Results Presented at the 8th Annual Targeted Therapies for the Treatment Of Lung Cancer Meeting
11. EndoGastric Solutions(TM) Announces Results of EsophyX(TM) Multi-Center GERD Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... 30, 2015  ResMed (NYSE: RMD ... definitive agreement to acquire Curative Medical, a ... sleep-disordered breathing medical devices and accessories. ... with ResMed,s global leadership in sleep and respiratory medicine, ... China suffering from sleep-disordered breathing ...
(Date:7/30/2015)... Calif. , July 30, 2015  EP ... /Alcon executives have recently contacted the Company about ... begin as early as Monday, August 3, 2015.  ... quoted as saying that the coming electronic contact ... of dollars over the next several years.  Novartis ...
(Date:7/30/2015)...  Amgen (NASDAQ: AMGN ) today announced ... Key results include: , Total revenues increased ... to $5,370 million, with 6 percent product sales ... Prolia ® (denosumab), Sensipar ® (cinacalcet), ... (denosumab). Unfavorable changes in foreign exchange rates impacted ...
Breaking Medicine Technology:ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 2Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 3Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 4Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 5Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 6Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 7Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 8Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 9Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 10Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 11Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 12Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 13Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 14Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 15Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 16Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 17Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 18Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 19Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 20Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 21Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 22Amgen's Second Quarter 2015 Revenues Increased 4 Percent To $5.4 Billion And Adjusted Earnings Per Share (EPS) Increased 8 Percent To $2.57 23
... LIONVILLE, Pa., Dec. 16, 2010 West Pharmaceutical Services, Inc. (NYSE: ... has approved payment of the first-quarter 2011 cash dividend of $0.17 ... to shareholders of record on January 19, 2011. ... of components and systems for injectable drug delivery, including stoppers and ...
... (Nasdaq: HSKA, "Heska" or the "Company"), announced today that ... Forever, has been awarded $25,000 as the grand prize ... (Logo: http://photos.prnewswire.com/prnh/20000622/HESKALOGO) Helping low-income ... their pets for as long as possible, Pets Forever ...
Cached Medicine Technology:Heska Corporation Awards $25,000 Grand Prize to Pets Forever 2
(Date:7/31/2015)... ... 31, 2015 , ... In the most recent testosterone lawsuit news ... District of Illinois, Androgel testosterone attorneys report that a “Mini Status Conference” was held ... recording the minutes of the status conference, which was held that day, according to ...
(Date:7/31/2015)... ... July 31, 2015 , ... People love to feel ... insurance, where price is an important factor to clients when choosing to purchase ... offers the Preferred Producer Multi-Life Discount program, where advisers pass savings onto their ...
(Date:7/30/2015)... ... July 31, 2015 , ... Reduce ... or More, **Presented by FDAnews and Ginette M. Collazo, Inc.**, Sept. 16-17, 2015 ... veteran of helping drug, biologic and device firms reduce manufacturing errors by 50 ...
(Date:7/30/2015)... ... 2015 , ... As more hospitals across the country see the value in ... challenge. Because of growing competition, it is more important than ever to market ... The team at Wound Care Advantage has found that while many hospitals ...
(Date:7/30/2015)... ... July 30, 2015 , ... Women's dating ... Lines ." It's for women interested in improving their love lives using specific ... which officially launched to the public early this morning, has drawn praise from ...
Breaking Medicine News(10 mins):Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 2Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 3Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 4Health News:Secura Consultants Gives Advisers Competitive New Edge with Multi-Life Discount Program 2Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 2Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 3Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 4Health News:WCA Offers Shockwave; The Marketing Module for Hospital Wound Care Programs 2Health News:WCA Offers Shockwave; The Marketing Module for Hospital Wound Care Programs 3Health News:WCA Offers Shockwave; The Marketing Module for Hospital Wound Care Programs 4Health News:Lovetraction Lines - Review Examining Simone Myers' New Online Course Released 2
... Steven Reinberg HealthDay Reporter , WEDNESDAY, Oct. 5 (HealthDay ... introduced the world to personal computers, then the iPod, the iPhone ... cancer. He was 56. "Apple has lost ... amazing human being," the company said in a statement it posted ...
... of strategies released today by the Commonwealth Fund Commission ... how the U.S. health care system serves vulnerable populationsthose ... of racial and ethnic minority groups. According to ... Achieve High Performance Health Care for Vulnerable Populations, closing ...
... AMHERST, Mass. -- New research based on post-hospital arrival ... adjusting for differences in injury severity, gun use, and ... assault, African-Americans have a significantly higher overall post-scene of ... by Anthony R. Harris, emeritus professor of sociology at ...
... 12 or older are estimated to have driven under the ... a 2009 National Survey on Drug Use and Health. While ... its role in causing crashes has remained in question. To ... of a car accident, researchers at Columbia University did a ...
... and run and how their knees look in an MRI ... decades in advance whether they will develop osteoarthritis, the common ... the time they reach the age of 70. Doctors ... scan and tell you definitively whether or not they will ...
... (HealthDay News) -- Technology that directly oxygenates the blood reduced ... by the H1N1 flu virus, a new British study shows. ... they noted that debate continues about the use of the ... called extracorporeal membrane oxygenation, which oxygenates the blood. It,s used ...
Cached Medicine News:Health News:Steve Jobs, Visionary Leader of Apple Inc., Dies at 56 2Health News:Steve Jobs, Visionary Leader of Apple Inc., Dies at 56 3Health News:Strategy for improving health care for uninsured, low-income, and minorities in the US 2Health News:Strategy for improving health care for uninsured, low-income, and minorities in the US 3Health News:Strategy for improving health care for uninsured, low-income, and minorities in the US 4Health News:Strategy for improving health care for uninsured, low-income, and minorities in the US 5Health News:Researchers find race disparity in post-hospital arrival homicide deaths at trauma centers 2Health News:Marijuana use may double the risk of accidents for drivers 2Health News:$6.3 million center at UCSF and UC Davis seeks ways to diagnose and prevent osteoarthritis 2Health News:$6.3 million center at UCSF and UC Davis seeks ways to diagnose and prevent osteoarthritis 3Health News:Oxygenating Blood of Hospitalized H1N1 Flu Patients Saved Lives: Study 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: