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Northwest Biotherapeutics Conducting Ovarian Cancer Clinical Trial With DCVax(R)-L at University of Pennsylvania
Date:12/27/2007

. These personal cancer biomarkers are then loaded onto the patient's own dendritic cells (the master cells responsible for starting and managing the body's overall immune response), and injected back into the patient through a simple intra-dermal injection, similar to an insulin shot, at various intervals over a period of up to three years.

About Northwest Biotherapeutics

Northwest Biotherapeutics is a biotechnology company focused on developing immunotherapy products that treat cancers more effectively than current treatments, without toxicity, on a cost-effective basis. The Company has two broad platform technologies: dendritic cell-based vaccines, and therapeutic antibodies. The Company is currently conducting a large clinical trial in Glioblastoma multiforme, which is designed and powered to serve as a pivotal trial. The Company has also received clearance from the FDA for a large Phase III trial in prostate cancer, and clearance from the FDA for Phase I trials in five other cancers. The Company also has a second technology platform, involving monoclonal antibodies to CXCR4, which is at the late pre-clinical development stage.

For further information, please visit the company web site at http://www.nwbio.com.

About the Ovarian Cancer Vaccine Initiative

The Ovarian Cancer Vaccine Initiative (OCVI) is a private philanthropic organization that is funding this NWBT trial at the Hospital of the University of Pennsylvania. Fundraising to underwrite the clinical trial, and translational research that supports it, is actively sought by the OCVI campaign heads and lead donors, Patricia Dunn and Randall Caudill. Donations in cash or stock, which qualify for tax-exemption, may be directed to:

Ovarian Cancer Vaccine Initiative

Account 9078-6137

Schwab Charitable Fund

101 Montgomery Street

San Francisco, CA 94104


SOURCE Northwest Biotherapeutics, Inc.
Copyright©2007 PR Newswire.
All rights reserved

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