Navigation Links
Node-Negative Early Stage Breast Cancer Patients Benefit from Taxotere(R)-Based Chemotherapy
Date:5/27/2008

mors > 5 cm; tamoxifen was given for 5 years to all patients with endocrine responsive tumors. A study amendment initiated during enrollment mandated the use of G-CSF with the first cycle of TAC, in order to reduce the incidence and severity of hematological toxicities and febrile neutropenia.

The primary end-point was DFS with analysis planned after a minimum follow-up of 5 years.

The full safety analysis has previously been published (Martin et al (2006), Ann Oncol 17: 1205-12). The analysis demonstrated that febrile neutropenia (grade 4) was the most common and clinically severe event (24.6%) reported with the TAC regimen. The incidence of febrile neutropenia decreased to 6.5% with the use of G-CSF from the first cycle of TAC. The incidence of febrile neutropenia among patients treated with FAC was 2.3%. Grade 2-4 anemia was higher in the TAC regimen (47.4%) vs FAC (7.5%). The incidence of anemia TAC decreased (27.5%) with the use of G-CSF. No toxic deaths were reported.

About Breast Cancer

According to the American Cancer Society, worldwide, breast cancer is the most common cancer in women and the second most common after lung cancer in both genders. More than one million new cases of breast cancer are reported worldwide annually and more than 400,000 women die each year from the disease.

In Europe, breast cancer is responsible for 27.3% of all new cancer cases among women and 20.22% of cancer deaths. The International Agency for Research in Cancer estimates that in 2004 there were 360,749 new breast cancer cases diagnosed while the number of deaths was 129,013.

According to the American Cancer Society, in general, breast cancer rates have risen about 30% in the past 25 years in western countries. In addition, the incidence is highest in western countries. This appears to be due to increased screening which detects breast cancer in earlier stages.

About GEICAM

GEICAM (Grupo Espanol de Investigacion en Cance
'/>"/>

SOURCE sanofi-aventis
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Nearly 60 New Studies of Oral Xeloda(R) (capecitabine) Featured at the 44th American Society of Clinical Oncology Annual Meeting
2. Early Esophageal Cancer and Pre-Cancer Eliminated With Non-Surgical Treatment Combination
3. AviaraDx Confirms That Combination of Two Molecular Biomarkers Improves Prediction of Disease Recurrence in Early Stage Breast Cancer Patients
4. TYKERB(R) (Lapatinib) to be Investigated in Landmark Early Breast Cancer Trial
5. Starting Flu Vaccination in August Could Help Protect Nearly 11 Million More Children During Scheduled Doctors Visits
6. Data Show Preoperative Assessment of Breast Cancer Patients Enables Early Diagnosis, Successful Treatment of Lymphedema
7. Quantum Immunologics, Inc. and the South Alabama Medical Science Foundation Announce an Early Clinical Evaluation of a Novel Immuno-therapeutic Vaccine for Treating Advanced Human Breast Carcinomas
8. Gene Therapy Provides Vision to People who Were Nearly Blind
9. Nostrum Announces the Successful Completion of Early Proof-of-Concept Study for its Novel Clot Busting Therapeutic Protein
10. Cardiums Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack
11. Study Shows Once-Yearly Reclast Better than Risedronate at Increasing Bone Mass in Patients With Osteoporosis Caused by Glucocorticoids
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... SAN DIEGO , Dec. 17, 2014 ... PHIA) and Volcano Corporation (NASDAQ: VOLC ), a ... applications, today announced that they have entered into a definitive ... tender offer to acquire all of the issued and outstanding ... total equity purchase price of USD 1 billion (approx. EUR ...
(Date:12/17/2014)... HOLBROOK, N.Y. , Dec. 17, 2014 /PRNewswire/ ... that The Depository Trust Company (DTC) has made ... the Deposit Chill on the Company,s stock effective ... of Northstar,s common stock for depository and book ... and the Company is now once again fully ...
(Date:12/17/2014)... 17, 2014  ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") (NYSE ... Trademark Office (USPTO) has issued a key patent ... immunotherapeutic vaccine targeting six tumor antigens that are ... Patent No. 8,871,211, which issued October 28, 2014, ... a dendritic cell composition comprising peptide epitopes of ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3ImmunoCellular Therapeutics Announces Issuance of Key Patent For ICT-107 Cancer Vaccine 2
... Jan. 22 Protalix,BioTherapeutics, Inc. (Amex: PLX ... concept results in an animal study conducted as ... is being conducted under the agreement the Company ... the technology transfer,arm of the Hebrew University of ...
... approved to reduce both A1C and LDL cholesterol, ... Inc.,announced that the United States Food and Drug ... glycemic control,(measured as hemoglobin A1C) in adults with ... or insulin, either alone or in,combination with other ...
Cached Medicine Technology:Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study 2Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study 3Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes 2Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes 3Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes 4Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes 5Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes 6Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes 7
(Date:12/21/2014)... The Oncology Institute of Hope and Innovation hosted their third ... The Hope for the Holidays Toy Drive is a way ... during the holiday season. This year, the toy drive was ... offices. This event continues to be successful year after year. ... managers and assistant managers came out and not only donated ...
(Date:12/20/2014)... 21, 2014 BambooIndustry.com is a professional ... . The business has recently shown its new engineered ... all its bamboo flooring models. , BambooIndustry.com’s customers come ... Asia and more. According to the CEO of the ... very fast in the past few years, and the ...
(Date:12/20/2014)... MissyDress, a distinguished special dress supplier, has just ... has drastically cut prices to all its prom dresses ... 30, 2015. Many of the hottest styles are sold ... dresses, and more. , A spokesman for MissyDress says, ... A-line princess prom dresses or sweetheart chiffon prom dresses, ...
(Date:12/20/2014)... An improving macroeconomic landscape and a ... Massage Services industry over the five years ... the anticipated 1.0% annualized increase in per capita disposable ... the means to afford additional massages. “While the share ... a given year has declined from 2009 to 2012, ...
(Date:12/20/2014)... 2014 DePuy Pinnacle hip lawsuits ... of the artificial hip system was defectively designed ... courts, Bernstein Liebhard LLP reports. According to an ... Court on December 2nd, counsel in 10 DePuy ... plaintiffs on November 19, 2014, with depositions to ...
Breaking Medicine News(10 mins):Health News:BammbooIndustry.com: Big Discounts On All Kinds Of Bamboo Flooring Collections 2Health News:MissyDress: The Prices of Prom Dresses Just Reduced 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 2Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 3Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 4
... new center to produce and sell human stem cells; ... the first ever in Europe,// envisaged to give an ... research. The Roslin Cells Center is a brain child ... Enterprise, Edinburgh University and the Scottish National Blood Transfusion ...
... A recent study reveals that islet cell transplantation may decrease ... diabetes. // ,This study conducted by James Shapiro, ... and his team was published in Thursday's New England Journal ... from dead donors were transplanted into 36 patients affected by ...
... Information on the Disease Control Priorities project that plans ... countries // was given to health ministers from the ... ,According to the Pan American Health Organization, ... of the "best buys" in health improvement in developing ...
... announced that it is adequately geared with a ... // control measures, to counter a potential chikungunya ... Ernakulum and Kozhikode have reported the chikungunya fever. ... the Health watch dogs, Ms. Sreemathy, Health Minister, ...
... of Radiology says that a mathematical formula can predict ... percent accuracy.// Researchers say this will allow doctors to ... of women have different levels of bone mineral density ... as to how physicians should assess their future fracture ...
... At the turn of the 20th century, tobacco baron James ... figure of 430 million, jabbed his finger at a map ... to sell cigarettes." ,One hundred years on, Duke's prophesy ... population has since grown to 1.3 billion, has been realised ...
Cached Medicine News:Health News:Formula Predicts Osteoporotic Fracture Risk 2Health News:World's 3 out of 10 Cigarettes Smoked in China 2
The 40D is ideal for pediatric ophthalmoscopy and other examinations requiring expansive fundus visibility. Alternatively, this lens may be used at the slit lamp biomicroscope to provide an extremely...
This excellent mid-power lens provides medium field and magnification, with an ideal diameter for grip andmanipulation in the orbital area....
The 15D provides high magnification along with an optimized working distance from the cornea. With its 4.11x magnification it is also well suited for disc and macular observation....
The Professional ophthalmoscope has been designed to ensure ultimate control. Lenses, graticules and filters can all be introduced at the touch of a fingertip without the need to pull away from the p...
Medicine Products: