Navigation Links
Nobel Prize Winner Bruce Beutler joins Sound Pharmaceuticals
Date:11/28/2012

SEATTLE, Nov. 28, 2012 /PRNewswire/ -- Sound Pharmaceuticals, Inc. is honored to have Bruce A. Beutler, a recipient of the 2011 Nobel Prize in Physiology or Medicine for his discoveries involving the activation of innate immunity, join the company as a scientific advisor. Dr. Beutler is currently the Director of the Center for the Genetics of Host Defense at the University of Texas Southwestern Medical Center. In addition, he has identified and characterized COMT2, a genetic mutation that leads to human deafness. "He is an expert in the molecular pathways and biology that are at the heart of our science, and is a tremendous addition to our Scientific Advisory Board," said Jonathan Kil, MD, Chief Medical Officer.

SPI has developed an orally delivered small molecule (SPI-1005) that is currently in mid-stage or Ph-II clinical trials for the prevention and treatment of noise induced hearing loss and chemotherapy induced ototoxicity and tinnitus. SPI found that the enzyme glutathione peroxidase 1 (GPx1) is diminished in several critical cells and tissues in the cochlea of mammals immediately following noise exposure. SPI-1005 treatment increases the expression of GPx1 and is thought to allow these affected cells and tissues to repair themselves, thus restoring auditory function and preventing the irreversible loss of auditory hair cells and supporting cells.

SPI is also developing a locally delivered drug for regenerating cells within the inner ear of mammals as a means to restore auditory function to the severely hearing impaired or deaf. By inhibiting p27Kip1, a cyclin dependent kinase inhibitor or CKI, supporting cell and auditory hair cell regeneration is stimulated in adult mice and Guinea pigs that were previously exposed to intense noise or ototoxic drugs. This novel prolif
'/>"/>

SOURCE Sound Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. The Galien Foundation Announces Roster of Luminary Presenters for Third Galien Forum; Program Highlights Include CEO Panel, Panel on Alzheimers Disease Innovation, Nobel Laureate Elie Wiesel
2. Breast Cancer Survivor Awarded Top Prize In 2012 Oncology On Canvas(SM) Art Competition
3. Archbishop Desmond Tutu and the International Childrens Peace Prize Winners Launch Remember2015
4. Women Health Expert GC-Rise Launches Obstetrician-gynecologist Prize
5. Building on a Legacy: Vinita Gupta, CEO of Lupin Pharmaceuticals, Inc., Named Ernst & Young U.S. 2012 Family Business Award of Excellence winner
6. West Virginia Rx Program Named a Mutual of America 2012 Community Partnership Award Winner
7. 2012 Facility of the Year Awards Program Names Mercks Vaccine Bulk Manufacturing Facility (VBF) Program of Projects as Overall Winner
8. Winner Medical Announces Mailing of Definitive Proxy Materials for Special Meeting of Shareholders
9. Goodwin Biotechnology is a Three-Category Winner in the 2012 CMO Leadership Awards
10. Tina Fehr, Senior Product Manager For AmLactin, Upsher-Smith Laboratories Named PM360 Trailblazer Winner For Womens Health Brand Manager
11. Elsevier and Australasian Research Management Society Announce Winners of the 2012 Scopus Young Researcher of the Year Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... , July 10, 2014 Decision Resources Group ... of the U.S. Food and Drug Administration,s (FDA) approval ... binder Velphoro, which was approved by the FDA in ... kidney disease (CKD) patients on dialysis. Other ... Nephrology (US) Q2 2014 : ...
(Date:1/15/2014)... 15, 2014 As health officials across the Midwest warn ... pharmacies in Michigan will offer free ... enabling Meijer pharmacists to administer tests and, in some cases, ... physician participating in the study. The ...
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) announces ... condition to the announced tender offer for all of the outstanding ... result of the waiver, the transaction is no longer conditional on ... January 24, 2014 following the currently scheduled expiration time, subject to ...
Breaking Medicine Technology:Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3
... Cardium Therapeutics,(Amex: CXM ) and its ... findings from a preclinical study, demonstrating a ... (cooling) for the potential,treatment of acute myocardial ... BioMed Central (BMC) Cardiovascular Disorders (2008, 8:7, ...
... - New Approach to Targeting the Tumor ... Halozyme Therapeutics,Inc. (Nasdaq: HALO ), ... the extracellular matrix, today,announced new pre-clinical findings ... the American Association for Cancer Research (AACR) ...
Cached Medicine Technology:Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 2Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 3Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 4Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 5Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 6Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 7Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 8Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 9Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 10Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 11Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 12Halozyme Therapeutics Presents Pre-Clinical Studies of Systemic Delivery of Pegylated rHuPH20 Enyzme in Prostate Cancer Models at American Association for Cancer Research Conference 2Halozyme Therapeutics Presents Pre-Clinical Studies of Systemic Delivery of Pegylated rHuPH20 Enyzme in Prostate Cancer Models at American Association for Cancer Research Conference 3Halozyme Therapeutics Presents Pre-Clinical Studies of Systemic Delivery of Pegylated rHuPH20 Enyzme in Prostate Cancer Models at American Association for Cancer Research Conference 4
(Date:7/10/2014)... According to a new market research ... Airborne, Naval), Application (Software Defined Radios, SATCOM, Encryption, ... America, Asia-Pacific, Europe, the Middle East & ROW) ... the market is estimated to be $30.15 billion ... CAGR of 5.56% to reach $39.52 billion by ...
(Date:7/10/2014)... 10, 2014 Best Drug ... that having family close by during a stay ... whether or not the process is successful, has ... website at http://www.bestdrugrehabilitation.com/success-stories/ . , The new ... testimonials from several Best Drug Rehabilitation graduates who ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Ivalua, ... latest results of the 4th “Trending in Procurement” ... model. , Every day multinational corporations process ... expense forms etc. To meet this challenge, more ... suites which can be defined as a suite ...
(Date:7/10/2014)... not nurture, may play the bigger role in the ... "As is the case in humans, genes matter ... William Hopkins of the Yerkes National Primate Research Center ... journal Current Biology . The findings might ... humans, Hopkins, team said. According to the researchers, ...
(Date:7/10/2014)... who are sensitive to light or noise after a ... as anxiety and depression, a new study says. ... teens experience after concussion may help in planning for ... to return to play and what accommodations are needed ... and Dong Han, of the University of Kentucky in ...
Breaking Medicine News(10 mins):Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Best Drug Rehabilitation Launches New Success Stories Section of Website 2Health News:‘Source-to-Pay’ e-Procurement Is Real Performance Driver for Purchasing Departments 2Health News:‘Source-to-Pay’ e-Procurement Is Real Performance Driver for Purchasing Departments 3Health News:Like Humans, Chimps' Smarts May Rely on Genes 2Health News:Some Teens May Face Emotional Problems After Concussion 2
... , , IRVING, Texas, ... (OTC Bulletin Board: RBCL), a provider of proprietary nutritional supplements and ... the ClearPay System, a compensation plan that rewards the company,s independent ... The ClearPay System is the ...
... , , , ... with painful conditions, September is a time for their true ... communication, National Pain Awareness Month allows people with painful conditions ... fight their pain. , , Fibromyalgia has ...
... of infections on campus already increasing rapidly; could ... , TUESDAY, Sept. 8 (HealthDay News) -- Erica Goldfine, ... to school this semester to find a new item ... cheating: emergency preparedness procedures for the H1N1 swine flu. ...
... , CLAREMONT, Calif., Sept. 8 ... that personalized medicine will have on life science companies, physicians, patients, ... "Personalized medicine will change how medicine is delivered," said Diana Bartlett, ... longer one size fits all. Your therapy may be different from ...
... Ala., Sept. 8 BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX ... two upcoming investor conferences. , , ... to present a corporate summary at the Rodman & Renshaw Annual ... Eastern Time. The conference will be held September 9-11, 2009 in ...
... , , JACKSONVILLE, Fla., Sept. 8 ... to getting the job done. Yet, new research reveals that as they ... to perform everyday activities at home and on the job. , ... are concerned that their vision is getting worse as they age, and ...
Cached Medicine News:Health News:RBC Life Sciences Unveils the ClearPay System - the Industry's First Balancing Compensation Plan That Pays Quickly and Abundantly 2Health News:RBC Life Sciences Unveils the ClearPay System - the Industry's First Balancing Compensation Plan That Pays Quickly and Abundantly 3Health News:Know Fibro Initiative Commemorates National Pain Awareness Month 2Health News:Know Fibro Initiative Commemorates National Pain Awareness Month 3Health News:Colleges Move to Limit Swine Flu's Spread 2Health News:Colleges Move to Limit Swine Flu's Spread 3Health News:Colleges Move to Limit Swine Flu's Spread 4Health News:KGI to Host Public Discussion on Personalized Medicine 2Health News:BioCryst Executives to Present at Two Investor Conferences 2Health News:Working Moms' Vision Not 'Near' Perfect 2Health News:Working Moms' Vision Not 'Near' Perfect 3
The Doro Halo retractor system is designed for all neurosurgical applications where retraction of the brain tissue and an armrest is required....
Molt 9, excellent for subperiosteal tunneling....
Love-Adson periosteal elevator, semi sharp, blade width 3/16" (5 mm), length 6 1/2" (165 mm)....
Iowa University periosteal elevator, blade width 11/16" (17 mm), length 7 1/4" (184 mm)....
Medicine Products: