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Nile Therapeutics Completes Dosing of Clinical Trial Evaluating the Subcutaneous Infusion of Cenderitide in Chronic Heart Failure Patients
Date:10/18/2011

he next trial," said Hsiao Lieu, MD, Vice President of Clinical Research at Nile. "We believe we understand cenderitide's pharmacokinetics and pharmacodynamics when administered through continuous subcutaneous infusion, and look forward to moving into the next phase of development."

"We are very encouraged by the data we have seen to date," said Joshua Kazam, Chief Executive Officer of Nile. "We are currently actively engaged in discussions with potential strategic and financial partners to ensure that we determine the best way to move forward with this exciting program in the best interests of our shareholders."

About Heart Failure

Heart failure is the fastest-growing clinical cardiac disease in the U.S. according to the American Heart Association, affecting over 5 million Americans. Over 1 million patients in the U.S. each year are hospitalized with ADHF, an acute exacerbation of heart failure. ADHF is the is the most frequent cause of hospital admission in the U.S. for patients older than 65 years, generating annual inpatient costs of more than $35 billion. Within 90 days following admission for ADHF, approximately 40% of patients return to the hospital. Nile believes that a decrease in the ADHF re-hospitalization rate, which is the clinical target of the cenderitide development program, could both improve the quality of life for patients and decrease the annual inpatient cost of heart failure.

About Nile Therapeutics

Nile Therapeutics, Inc. is a biopharmaceutical company that develops innovative products for the treatment of cardiovascular disease and other areas of unmet medical needs. Nile is initially focusing its efforts on developing its lead compound, cenderitide, a novel rationally designed chimeric peptide in clinical studies for the treatment of heart failure, and CU-NP, a novel rationally designed natriuretic peptide. More information on Nile can be found at http://
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SOURCE Nile Therapeutics, Inc.
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