Navigation Links
Niiki Pharma Forms Scientific Advisory Board with Leading U.S. Oncologists
Date:2/1/2012

HOBOKEN, N.J. and PHILADELPHIA, Feb. 1, 2012 /PRNewswire/ -- Niiki Pharma Inc. announced today the formation of its Scientific Advisory Board. Daniel Haller M.D. will chair the advisory board, and will be joined by Lee Ellis M.D. and Matt Kulke M.D. The Board will provide clinical and strategic guidance to the company for its two first-in-class clinical stage anti-cancer compounds, NKP-1339 and NKP-2235. As the pipeline continues to mature, the Advisory Board will be expanded.

The initial focus of the board will be Niiki Pharma's promising lead compound, NKP-1339. NKP-1339, a small molecule that down-regulates GRP78, has recently completed the dose-escalation portion of its Phase I clinical trial.

"Although we have an increasing number of drugs for a diverse spectrum of diseases, new drugs that may have higher benefit and lower toxicity for our patients are always needed," said Dr. Haller. "This Board welcomes the opportunity to participate in the development of these agents."

Dr. Daniel Haller is internationally renowned in the field of oncology. He is currently Professor of Medicine in the Department of Medicine at the Abramson Cancer Center at the University of Pennsylvania. In addition to his leadership in clinical research throughout the NCI and cancer cooperative group system, Dr. Haller is currently co-chair of the NCI Gastrointestinal Intergroup. He served as Editor-in-Chief of the Journal of Clinical Oncology, the official journal of the American Society of Clinical Oncology (ASCO), was the Associate Editor of the Annals of Internal Medicine and was Editor-in-Chief of PDQ, the National Cancer Institute's cancer information database.

Dr. Lee Ellis is an internationally recognized surgical oncologist, researcher, and leader in the field of translational oncology. He holds several positions at University of Texas MD Anderson Cancer Center, including Professor of Surgery and Cancer Biology; Director, Metastasis Research Center; Director, Colorectal Cancer Translational Research Program; and Chair, Ad Interim, Department of Cancer Biology. Dr. Ellis is vice-chair of the NCI Colon Cancer Task Force and serves on 8 editorial boards, including Journal of Clinical Oncology, Cancer Research and Clinical Cancer Research. Dr. Ellis has served in leadership roles in major cancer societies including ASCO, American Association for Cancer Research, and the Society for Surgical Oncology.

Dr. Matthew Kulke is a world expert in neuroendocrine (NET) tumors. He is Associate Professor of Medicine at Harvard Medical School and Dana-Farber Cancer Institute, where he leads the Carcinoid and Neuroendocrine Tumor Program. He has a leadership role in the Cancer and Leukemia Group B (CALGB) Gastrointestinal Cancer Committee, chairs the NCI NET Task Force and NCCN NET guidelines committees, and serves on the executive committee of the North American Neuroendocrine Tumor Society. Dr. Kulke has chaired multiple global pivotal studies exploring new therapies for NET.

About NKP-1339
NKP-1339 is a first-in-class small molecule anti-cancer compound that down-regulates GRP78, a known tumor survival and anti-apoptosis factor. In preclinical studies, NKP-1339 has demonstrated activity against multiple tumor types. In the Phase I trial, antitumor activity was seen against multiple cancers, including NET.

About NKP-2235
NKP-2235 is a first-in-class orally available small molecule that targets the endoplasmic reticulum with a unique pattern of cytotoxicity. NKP-2235 IND has been cleared and a Phase I trial will be initiated shortly.

NKP-1339 and NKP-2235 were discovered by Professor Bernhard Keppler, University of Vienna, Austria.

About Niiki Pharma Inc.
Niiki Pharma (www.niikipharma.com) is a development focused oncology company specializing in first-in-class cancer treatments directed at novel tumor targets and related companion diagnostics.


'/>"/>
SOURCE Niiki Pharma Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Novel First-in-Class Anti-Cancer Agent in Development by Niiki Pharma Shows Promising Phase I Results
2. Niiki Pharma Announces Positive Interim Data from Ongoing Clinical Trial of Novel Anti-Cancer Agent NKP-1339
3. Niiki Pharma Reports on Synergistic Activity of Novel Anti-Cancer Agent NKP-1339 with Other Anti-Cancer Agents
4. Niiki Pharma Announces the Completion of Phase I Dose Escalation for First-in-Man Anti-Cancer Agent NKP-1339
5. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
6. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
7. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
8. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
9. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
10. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
11. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... , April 25, 2017 Endo International plc (NASDAQ: ... May 9, 2017. Members of its senior management team will host ... at 8:30 a.m. ET. The dial-in number to ... International (678) 509-7598, and the passcode is 6086379. Please dial in ... A replay of the call will be available ...
(Date:4/20/2017)... April 20, 2017  Vivify Health, the pioneer and ... been awarded a very significant patent for the advancement ... continual care via digital health.  This landmark patent provides ... and further secures Vivify,s position as the leader in ... was the first company to apply consumer mobile devices, ...
(Date:4/20/2017)... 2017  CVS Pharmacy, the retail division of ... store design to enhance the retail customer experience ... products and expanded beauty selections paired with informational ... new offerings. Together with its innovative digital programs, ... customer experience at CVS Pharmacy.  ...
Breaking Medicine Technology:
(Date:4/28/2017)... Tenn. (PRWEB) , ... April 28, 2017 , ... ... system, today announced an alliance with B. Braun Medical Inc. , a leader ... role in patient care with as many as 90 percent of hospital patients receiving ...
(Date:4/27/2017)... ... April 27, 2017 , ... ... deodorant. On the heels of Thinksport’s award-winning sunscreen they’ve used the same scientific ... actually works! , Countless deodorants flood the aisles that contain harmful chemicals that ...
(Date:4/27/2017)... ... April 27, 2017 , ... Goodcents Deli Fresh Subs announced a franchise expansion ... this year. , The first new location will open at the corner of ... 84th and Northern Lights Drive this fall. And the third location is in the ...
(Date:4/26/2017)... ... April 26, 2017 , ... Jump Technologies, Inc., an innovative ... has completed a round of funding to accelerate its growth strategies. The $3.5 ... Capital is a growth equity firm focused on investments in healthcare and technology ...
(Date:4/26/2017)... ... April 26, 2017 , ... ... describes the adoption of e-prescribing as measured in Part D Medicare data. The ... prescriptions to pharmacies, either using e-prescribing, faxes or paper. The PaPR (pronounced ...
Breaking Medicine News(10 mins):