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NicOx' Naproxcinod ABPM Data Presented at American Heart Association
Date:11/7/2007

ing the completion of the 302 and 303 studies. NicOx anticipates filing a New Drug Application for naproxcinod in the United States during the first quarter of 2009.

NOTE 1: Systolic blood pressure is the maximum pressure in the arteries

when the heart is contracting, while diastolic pressure is the

lowest pressure between heart beats.

NOTE 2: Office blood pressure measurements (OBPM) are made by a health

care professional during a subject's visit to their treatment

center using standard equipment (i.e. a sphygmomanometer).

NicOx (Bloomberg: COX: FP; Reuters: NCOX.PA) is a product-driven biopharmaceutical company dedicated to the development of nitric oxide-donating drugs to meet unmet medical needs. NicOx is targeting the therapeutic areas of inflammation and cardio-metabolic disease. Resources are focused on two lead compounds, naproxcinod (formerly HCT 3012); in phase 3 development for the treatment of signs and symptoms of osteoarthritis, and NCX 4016, in phase 2 for type 2 diabetes.

NicOx has strategic partnerships with some of the world's leading pharmaceutical companies, including Pfizer Inc. and Merck & Co., Inc.

NicOx S.A. is headquartered in Sophia-Antipolis, France, and is a public company listed on the Eurolist of Euronext(TM) Paris (segment: Next Economy).

The elements included in this communication may contain forward-looking statements subject to certain risks and uncertainties. Actual results of the company may differ materially from those indicated in the forward-looking statements because of different risks factors described in the company's document de reference.


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SOURCE NicOx S.A.
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