Navigation Links
NicOx Announces Blood Pressure Analysis From 301 Phase 3 Study for Naproxcinod at EULAR
Date:6/13/2008

acy end points, like the Modified Osteoarthritis Research Society International (OARSI) responder rate, a visual analog scale (VAS) of pain intensity during rest or walking and investigators' overall rating of disease status, treatment and response to therapy, also showed positive results.

Study design: 301 was a 13-week, double-blind, placebo and naproxen- controlled trial, in patients with osteoarthritis of the knee. 918 eligible patients were randomized on a 1:1:1:1 basis at 120 clinical sites in the United States to receive: naproxcinod 375 mg bid, naproxcinod 750 mg bid, naproxen 500 mg bid or placebo bid. Eligible patients were at least 40 years old, with a clinical diagnosis of primary osteoarthritis of the knee of at least 3 months duration, confirmed by radiographs, and diagnosed according to the ACR guidelines (patients must have qualified as ACR global functional status I, II or III). There were no statistically significant differences among the four treatment groups for any baseline variables, including hypertension medical history (approximately half of enrolled patients had a medical history of hypertension at baseline).

NicOx (Bloomberg: COX:FP, Reuters: NCOX.PA) is a product-driven biopharmaceutical company dedicated to the development and future commercialization of investigational drugs for unmet medical needs. NicOx is applying its proprietary nitric oxide-donating technology to develop an internal portfolio of New Chemical Entities (NCEs) in the therapeutic areas of inflammatory and cardio-metabolic disease.

Resources are focused on the development of naproxcinod, a proprietary NCE and the first compound in the Cyclooxygenase-Inhibiting Nitric Oxide-Donating (CINOD) class of anti-inflammatory agents, which is in phase 3 clinical studies for the treatment of the signs and symptoms of osteoarthritis, with final phase 3 results anticipated in 2008.

Beyond naproxcinod, NicOx has a pipeline containing multiple nitric oxide-
'/>"/>

SOURCE NicOx S.A.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. NicOx Completes Patient Enrollment in Third Naproxcinod Pivotal Phase 3 Study
2. NicOx Announces Initiation of First Phase 1 Study of Investigational Nitric Oxide-Donating Agent in Hypertensive Patients by Merck & Co., Inc.
3. Financial Results for Full Year 2007: NicOx Significantly Advances Clinical Programs
4. NicOx Announces Pfizer Initiates Phase 2 Clinical Development for PF-03187207 in Japan
5. NicOx Completes Enrollment in Second Pivotal Phase 3 Study for Naproxcinod and Provides Development Update
6. NicOx Announces TOPIGEN Initiates Phase 2 Proof of Concept Study in COPD for TPI 1020
7. NicOx Naproxcinod Phase 3 Results Presented at American College of Rheumatology
8. NicOx Naproxcinod ABPM Data Presented at American Heart Association
9. NicOx and Ferrer Present Promising Clinical and Preclinical Results in Dermatology
10. NicOx Reports TOPIGEN to Advance TPI-1020 Into Phase 2 for COPD Following Promising Clinical Results
11. Vion Pharmaceuticals Announces Presentation of Data of Cloretazine(R) (VNP40101M) in Elderly Patients with High-Risk Myelodysplastic Syndromes at the EHA Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... WORTH, Texas , April 27, 2015 ... market is segmented based on type, application, and geography and ... at $728.9 million in 2014, and is expected to reach ... the forecast period. Browse through the TOC of ... idea of the in-depth analysis provided. This also provides a ...
(Date:4/27/2015)... April 27, 2015  Eiger BioPharmaceuticals, Incorporated today announced ... of lonafarnib in patients with chronic hepatitis delta viral ... program, enrolled at Ankara University Medical School, ... endemic. LOWR HDV - 1 (LOnafarnib ... study which randomized subjects to receive different doses of ...
(Date:4/27/2015)... NEW YORK , April 27, 2015 /PRNewswire/ ... market for electronic medical records (EMR) to grow ... for US healthcare providers, according to a recent ... system upgrades, international sales and continued efficiency improvements ... each year for the next five years.  The ...
Breaking Medicine Technology:North America Optical Microscopy Market is Expected to Reach $829.9 Million by 2019, at a CAGR of 3.0% From 2014 to 2019 2North America Optical Microscopy Market is Expected to Reach $829.9 Million by 2019, at a CAGR of 3.0% From 2014 to 2019 3Eiger Bio Announces Interim Results of Lonafarnib in Combination with Ritonavir or Pegylated Interferon in Patients Infected with Hepatitis Delta Virus (HDV) 2Eiger Bio Announces Interim Results of Lonafarnib in Combination with Ritonavir or Pegylated Interferon in Patients Infected with Hepatitis Delta Virus (HDV) 3Kalorama: EMR Market Expected To Grow Beyond Incentives 2Kalorama: EMR Market Expected To Grow Beyond Incentives 3
... , WALTHAM, Mass., Dec. 15 Decision Resources, one of ... healthcare issues, finds that an overall survival benefit would be ... in their decision to prescribe a novel agent ahead of ... Special European Physician & Payer Forum report entitled European ...
... BEND, Oregon, December 15 Bend Research Inc. ... for HPMCAS, an,excipient used in technologies developed by the firm to ... Bend Research clients may now reference a Type V Drug ... Research officials said. , "We,re excited about ...
Cached Medicine Technology:For Breast Cancer Treatment, an Agent That Can Achieve an Overall Survival Benefit Would Pose the Greatest Challenge to Avastin's Dominance in Europe 2For Breast Cancer Treatment, an Agent That Can Achieve an Overall Survival Benefit Would Pose the Greatest Challenge to Avastin's Dominance in Europe 3Bend Research Clients May Now Reference Key Safety Document for Important Solubility Excipient 2
(Date:4/27/2015)... Orlando, Florida (PRWEB) April 27, 2015 Attorney ... , well-known for serving and protecting his clients, took that ... #Dan, an abbreviated dialing code which makes it easier for ... With an eye on building his brand and added value ... and the Greater Chicago area where Newlin has law offices. ...
(Date:4/27/2015)... (PRWEB) April 27, 2015 The Global ... grow at a CAGR of 5.9% during the period ... share in the materials healthcare packaging market, mainly due ... Global Pharmaceutical Packaging market is extremely fragmented with ... a major portion of the market with the rest ...
(Date:4/27/2015)... FL (PRWEB) April 27, 2015 Puroast Coffee ... nationwide tour for 2015. The BattleFrog OCR is a ... created to both educate participants in the training that Seals ... “We are thrilled to be able to sponsor the BattleFrog ... unique fitness experience that we find well-suited to give people ...
(Date:4/27/2015)... 27, 2015 Consumer Choice Award ... Providers in their respective sectors for Ottawa. We would ... winners; your dedication to superior service has resonated with ... Consumer Choice Award gathers opinions, perceptions and expectations through ... winners have gone through a rigorous selection process conducted ...
(Date:4/27/2015)... Colorado (PRWEB) April 27, 2015 ... ground-breaking solution to a problem that has been ... and advertising campaigns: by announcing the launch ... of its kind. , Officially launched today, ... and was created to index only marijuana-related business ...
Breaking Medicine News(10 mins):Health News:Dan Newlin Hashtags It With #Dan 2Health News:Global Pharmaceutical Packaging Market to Grow at 5% CAGR to 2019 Says a New Report at RnRMarketResearch.com 2Health News:Global Pharmaceutical Packaging Market to Grow at 5% CAGR to 2019 Says a New Report at RnRMarketResearch.com 3Health News:Global Pharmaceutical Packaging Market to Grow at 5% CAGR to 2019 Says a New Report at RnRMarketResearch.com 4Health News:Puroast Coffee on Tour with BattleFrog 2Health News:2015 Ottawa Consumer Choice Award-Winners 2Health News:2015 Ottawa Consumer Choice Award-Winners 3Health News:2015 Ottawa Consumer Choice Award-Winners 4Health News:2015 Ottawa Consumer Choice Award-Winners 5Health News:2015 Ottawa Consumer Choice Award-Winners 6Health News:2015 Ottawa Consumer Choice Award-Winners 7Health News:The WeedLife Network debuts its ground-breaking WeedLIVE cannabis industry search engine 2Health News:The WeedLife Network debuts its ground-breaking WeedLIVE cannabis industry search engine 3
... clues to the impact of severe physical, psychosocial suffering, ... Among Jewish survivors of World War II, those who ... risk of cancer, likely due to physical and mental ... Haifa researchers compared cancer rates in more than 300,000 ...
... women, wide waists in men spell trouble, study finds , ... body fat appears to affect the risk of dangerous blood ... women, a new Danish study indicates. , The 10-year study ... of venous thromboembolism (VTE) in women but not men, while ...
... habits can stave off the inevitable declines, research finds , ... that accompany growing old typically speed up after the age ... can slow the inevitable by staying lean, exercising and refraining ... issue of the Archives of Internal Medicine , are ...
... say , MONDAY, Oct. 26 (HealthDay News) -- There,s ... the family safe on Halloween. Some simple precautions will ... , The American Academy of Pediatrics offers the following ... and reflective and short enough to prevent tripping, entanglement ...
... shows they have doubled risk of GERD, may be linked ... World Trade Center rescue workers can add another illness to ... exposure to Ground Zero toxins and the ensuing mental anguish ... A new study shows that 41 percent of World Trade ...
... Oct. 26 Uno Chicago Grill®, America,s Healthiest Chain Restaurant(1), ... fall menu. , This exciting fall menu stars ... are a well-known and popular accent to many dishes, UNO ... the territory of a select few health food aficionados. ...
Cached Medicine News:Health News:Exposure to Holocaust May Have Raised Cancer Risks 2Health News:Where You Put on Pounds May Influence Clot Risk 2Health News:Fitness Fades Fast After 45 2Health News:Fitness Fades Fast After 45 3Health News:Treat Kids to a Safe Halloween 2Health News:World Trade Center Workers Have More Cases of Acid Reflux 2Health News:World Trade Center Workers Have More Cases of Acid Reflux 3Health News:Go, Go, Goji! UNO(R) Fall Menu Is 'Berry' Delicious 2Health News:Go, Go, Goji! UNO(R) Fall Menu Is 'Berry' Delicious 3
Sinskey lens manipulator, straight. Also available in titanium....
ICL manipulator with textured hemi-ball tip...
Vaulted shank with guard....
... Keeler ophthalmoscopes are individually adjusted for ... the eye, not on paper. This, along ... infinity focus, ensures that whatever the patient's ... and largest field of view. Lithium-ion technology ...
Medicine Products: