for
Nexavar and 4% in placebo. The incidence of treatment-emergent cardiac
ischemia/infarction was 2.7% for Nexavar vs. 1.3% for placebo. Most common
adverse events reported with Nexavar in patients with unresectable HCC were
diarrhea, fatigue, abdominal pain, weight loss, anorexia, nausea and
hand-foot skin reaction. Grade 3/4 adverse events were 45% for Nexavar vs.
32% for placebo. Women of child-bearing potential should be advised to
avoid becoming pregnant and advised against breast-feeding. In cases of any
severe or persistent side effects, temporary treatment interruption, dose
modification or permanent discontinuation should be considered.
For information about Nexavar including U.S. Nexavar prescribing
information, visit http://www.nexavar.com or call 1.866.NEXAVAR
(1.866.639.2827).
About Bayer HealthCare Pharmaceuticals Inc.
Bayer HealthCare Pharmaceuticals Inc. is the U.S.-based pharmaceuticals
unit of Bayer HealthCare LLC, a division of Bayer AG. One of the world's
leading, innovative companies in the healthcare and medical products
industry, Bayer HealthCare combines the global activities of the Animal
Health, Consumer Care, Diabetes Care, and Pharmaceuticals divisions. In the
U.S., Bayer HealthCare Pharmaceuticals comprises the following business
units: Women's Healthcare, Diagnostic Imaging, Specialized Therapeutics,
Hematology/Cardiology and Oncology. The company's aim is to discover and
manufacture products that will improve human health worldwide by
diagnosing, preventing and treating diseases.
About Onyx Pharmaceuticals, Inc.
Onyx Pharmaceuticals, Inc. is a biopharmaceutical company committed to
improving the lives of people with cancer. The company, in collaboration
with Bayer HealthCare Pharmaceuticals, Inc., is developing and marketing
Nexavar(R) (sorafenib) tablets, a small molecule drug. For more information
about Onyx, visit the company's website at '/>"/>
SOURCE Bayer HealthCare Pharmaceuticals, Inc.; OnyxPharmaceuticals, Inc. Copyright©2008 PR Newswire. All rights reserved | |
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