Navigation Links
Nexavar Significantly Improves Overall Survival by 47 Percent in Asia-Pacific Liver Cancer Study
Date:5/15/2008

- Trial Results Confirm Efficacy for Population Most Affected by Disease -

WAYNE, N.J. and EMERYVILLE, Calif., May 16 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that Nexavar(R) (sorafenib) tablets significantly improved overall survival by 47.3 percent (HR=0.68; p-value=0.014) in patients in the Asia-Pacific region with advanced hepatocellular carcinoma (HCC), or primary liver cancer versus those receiving placebo. Nexavar also significantly improved time to progression in these patients by 74 percent (HR=0.57; P=0.001). These data were presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) and further confirm Nexavar's efficacy in liver cancer.

The international, Phase 3, randomized trial evaluated efficacy and safety of Nexavar versus placebo in 226 Asian patients with advanced HCC who had not received prior systemic therapy. The study was designed to compare overall survival, time to progression, time to symptomatic progression, response as defined by RECIST criteria and safety in patients receiving Nexavar versus placebo. Median overall survival was 6.5 months in patients treated with Nexavar versus 4.2 months for those taking placebo. The survival benefit was seen across multiple patient subsets analyzed, including age, extrahepatic spread and/or macroscopic vascular invasion.

"Liver cancer in the Asia-Pacific region continues to grow because of a high incidence of chronic hepatitis B viral infections, which now impact approximately 275 million people in the region," said Ann-Lii Cheng, MD, PhD, Department of Internal Medicine and Department of Oncology, National Taiwan University Hospital, Taipei, T
'/>"/>

SOURCE Bayer HealthCare Pharmaceuticals, Inc.; OnyxPharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

1

GOOD

Page: 1 2 3 4 5 6

Related medicine technology :

1. Nexavar First FDA-Approved Drug Therapy for Liver Cancer
2. ZymoGenetics Reports Positive Phase 1 Results for IL-21 With Nexavar(R)
3. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
4. Study Demonstrates Lexapro(R) Significantly Improves Depression Symptoms in Adolescents
5. Patients Treated with Risperidone Long-Acting Injection had a Significantly Longer Time to Relapse Compared to Quetiapine in International Clinical Study
6. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
7. Data Presented at the American Academy of Neurology Show XP13512/GSK1838262 Significantly Improved Symptoms of Moderate-to-Severe Primary Restless Legs Syndrome
8. Data Presented at AAN Show That Lacosamide Significantly Reduced Pain and was Generally Well Tolerated in Patients With Diabetic Neuropathic Pain
9. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
10. Orqis(R) Medicals Cancion(R) System Significantly Increases Cardiac Performance
11. CV Therapeutics Anti-Ischemic Therapy Ranexa(R) Significantly Reduces Cardiac Chest Pain Symptoms and Recurrent Ischemia in MERLIN-TIMI 36 Patients With Angina

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2009)...Nov. 6 The ,Help is Her...lina and Georgia throughout the week of November 9...nd financially-struggling patients access informat...s for free or nearly free. With the nation,s unemp...ship for Prescription Assistance (PPA) bus tour is...
(Date:11/6/2009).... 6 Derma Sciences, In...anced wound care products, announced plans to rele...n Monday, November 16, 2009. The Company will hold...sults at 11:00 am EST. Interested parties should c...nternational), with passcode 81416481 to access th...
(Date:11/6/2009)...RNewswire-FirstCall/ -- NuVasive, Inc. (Nasdaq: N...ing products for minimally disruptive surgical tre...ment of Michael J. Lambert as Executive Vice Presi...er 9, 2009. The Company also announced several ot...ael will be an excellent complement to the NuVasiv...
Breaking Medicine Technology:Partnership for Prescription Assistance Prepared to Help Southern Workers Hurt by Recession 2Partnership for Prescription Assistance Prepared to Help Southern Workers Hurt by Recession 3Derma Sciences Announces Date of Its Third Quarter 2009 Earnings Release and Conference Call 2NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 2NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 3NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 4NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 5Respect Life and the Truth on Respect Life Sunday 58814 1Respect Life and the Truth on Respect Life Sunday 58814 2Respect Life and the Truth on Respect Life Sunday 58814 3NHIT Processes Over 4 000 Production Transactions Advances Adoption of NHIN Initiative 58809 1NHIT Processes Over 4 000 Production Transactions Advances Adoption of NHIN Initiative 58809 2Brookdale to Present at JMP Securities Healthcare Focus Conference 58804 1
... Researchers Identify Simple Test To Help Survivor...scular Fitness Level , , WASHINGTON, May 28 The ...s not affected by many standard cancer therapies, ...al Cancer. That is the finding of a new observati...ollege of Sports Medicine in Seattle. , , "We k...
... a First, Immunotherapy Works Against Neuroblastom...arch team has announced encouraging results for an... immune system to improve cure rates for children ...rvous system. , , John M. Maris, M.D., chief of O..., co-authored the phase 3 clinical trial, which wa...
Other Medicine Technology:Cardiovascular Fitness Not Affected by Cancer Treatment 2Cardiovascular Fitness Not Affected by Cancer Treatment 3New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer 2New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer 3
(Date:11/9/2009)... Leading U.S. air ambulance company now the...I accreditation and Department of Defense approval...) November 9, 2009 -- AirMed International, the le...it has earned full accreditation from the European...ttgart, Germany, based non-profit association of a...
(Date:11/9/2009)... One of the top cosmetic surgeons in Dallas...njamin Bassichis, MD, FACS, has recently published...juvenation in the Facial Plastic Surgery Clinics o...lastic and Reconstructive Surgeon, Dr. Bassichis&r...g-term facial filler treatments to achieve the mos...
(Date:11/9/2009)... -- Gifted young athletes are under increasing pre... new Loyola University Health System study of 519 ...zation increases the risk of injury. Researchers w...Association junior competition found that players ... withdraw from tournaments for medical reasons, ty...
(Date:11/8/2009)...Nov. 8 Today, the natio...es on passing, the Affordable Health Care for Amer...mportant step in reforming America,s healthcare sy...s Annual Meeting in Providence (RI), mayors from a...care reform principles of reducing the long-term g...
(Date:11/8/2009)..., Nov. 8 The American P...ntion and wellness provisions in the health reform...passage of this bill, the House takes important st...t insurance reforms and moving our health system f...hat focuses on keeping people healthy," said Georg...
Breaking Medicine News(10 mins):Health News:AirMed International, Top U.S. Air Ambulance, Receives EURAMI Accreditation 2Health News:Dallas Facial Plastic Surgeon Publishes Cutting-Edge Novel Approach To Facelift Technique 2Health News:Young tennis players who play only 1 sport are more prone to injuries 2Health News:The Nation's Mayors Commend House Passage of Health Reform Bill 2Health News:APHA Applauds Prevention and Wellness Provisions in House Health Reform Bill 2
...Feb. 14 Findings released today at the Oncology N...ancer Nursing Research reveal that isolation was t...African American women with breast cancer. The stu...isconnection and the sociocultural influences that...
.... 14 Trust for America,s Health (TFAH) commends t...on for prevention and wellness in the American Rei...t will support more than 20,000 public health jobs...said Jeff Levi, PhD, Executive Director of TFAH. ...
.... 13 The American Public Health Association (AP...her on the economic stimulus bill to produce legis...l governments to continue offering critical safety...ollowing, all of which are supported by APHA as im...
...ops among women at certain times of year, study fi...- Seasonal changes can interfere with people,s att...dy that found that women work out more in the summ...ter readings, the women,s step counts averaged mor...
.... 13 /PRNewswire-FirstCall/ - Hard to Treat Diseas...d negotiations to merge with a health care UK base...ct which is marketed in many European countries, a... HTDS Andrea Zecevic-Rubio, Chief Project Scientis...
.... 13 Six Miami-Dade County residents have been in...edicare fraud scheme operated out of Midway Medica...treating HIV/AIDS patients, Acting Assistant Attor...ourdes del Cueto, M.D., 65, Roberto Rodriguez, M.D...
Other Medicine News:Health News:Social Disconnection in African American Women With Breast Cancer 2Health News:Trust for America's Health Commends Congress, Obama Administration for Historic Investment in Prevention and Wellness 2Health News:APHA Applauds Congress for Stimulus Bill Compromise; Health Provisions Are Step in Right Direction 2Health News:Winter's Cold, Summer's Heat Take a Toll 2Health News:Hard To Treat Diseases (HTDS) Negotiating to Merge with a UK Health Care Company 2Health News:Three Miami Physicians and Three Medical Workers Charged With $10 Million Medicare Fraud Scheme 2
Protein A, Gold Ribbon - .13 OD per sq. cm.
Protein A, Gold Ribbon - .25 OD per sq. cm.
Dressed Gold, Protein A
Protein G Samples Pack - .13 OD ; .25 OD; .50 OD per sq. cm
Medicine Products: