Navigation Links
Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
Date:8/26/2007

Trial to be Stopped Early to Allow All Patients Access to Nexavar

WAYNE, N.J. and EMERYVILLE, Calif., Aug. 27 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals (NYSE: BAY) and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that a planned review by an independent data monitoring committee (DMC) found that Nexavar(R) (sorafenib) tablets significantly improved overall survival, progression free survival, and time to progression in an Asia-Pacific regional Phase 3 trial of patients with advanced hepatocellular carcinoma (HCC), the most common form of liver cancer. Based on the DMC's recommendation, the trial will be stopped to allow all patients to receive treatment with Nexavar. Data from this study will be submitted for presentation at an upcoming scientific meeting.

The Asia-Pacific liver cancer study was conducted at the request of Asian health authorities in order to provide supplemental information on Nexavar's efficacy and safety in Asia-Pacific patient populations. Supplemental regulatory filings have been completed in several countries/regions including Europe, China and the United States for Nexavar in the treatment of liver cancer. These filings were based on positive data from the pivotal Phase 3 SHARP study announced earlier this year. Additional regulatory submissions for Nexavar in liver cancer are being finalized.

"Liver cancer incidence continues to rise in the Asia-Pacific region, due to the high prevalence of hepatitis B vi
'/>"/>

SOURCE Bayer HealthCare Pharmaceuticals Inc.; Onyx
Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Nexavar Significantly Extends Overall Survival by 44% in Liver Cancer Patients
2. Review of Nexavar Data Presented at ASCO 2007- Investor Conference Call on June 4, 2007
3. Liraglutide provides significantly better glucose control than insulin glargine in phase 3 study
4. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
5. Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
6. Lumiracoxib Study Showed Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
7. Actemra (tocilizumab) Significantly Improves Symptoms of Rheumatoid Arthritis Compared to a Current Standard of Care
8. Next Safety, Inc.s Innovative Drug Delivery System Will Replace Cigarettes and Significantly Advance Pulmonary Medication Delivery
9. Ivivis PEMF Technology Significantly Improves Neuron Survival in Parkinsons Disease Model, Study Finds
10. Mercks Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study
11. The Eloxatin-Based Regimen (FOLFOX4) Significantly Improved Progression Free Survival When Given Before and After Surgery in Patients With Resectable Liver Metastases From Colorectal Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/3/2015)...  VA North Texas Health Care System announces ... a technology-based, scientifically advanced weight loss therapy.  ... the Maestro® Rechargeable System that intermittently blocks intra-abdominal ... food intake and processing between the brain and ... to meet the needs of a patient,s changing ...
(Date:6/3/2015)... , June 3, 2015 ... a biotechnology company focused on discovering and ... of dermatology and ophthalmology, today announced that it ... United States Patent and Trademark Office (USPTO) ... The patent, titled "RNA Interference in Ocular ...
(Date:6/3/2015)... BOSTON , June 3, 2015 PillPack, ... has completed a $50 million round of financing led ... Menlo Ventures, and Sherpa Ventures. The capital will be ... world-class team, and build retail pharmacies in US markets. ... and launched a better, simpler pharmacy experience that folks ...
Breaking Medicine Technology:VA North Texas First VA in the Country to Perform vBloc Implant, a Cutting-Edge Weight Loss Therapy 2VA North Texas First VA in the Country to Perform vBloc Implant, a Cutting-Edge Weight Loss Therapy 3RXi Pharmaceuticals Granted Notice of Allowance for Patent Covering Lead Compound, RXI-109, for Use in the Eye 2RXi Pharmaceuticals Granted Notice of Allowance for Patent Covering Lead Compound, RXI-109, for Use in the Eye 3RXi Pharmaceuticals Granted Notice of Allowance for Patent Covering Lead Compound, RXI-109, for Use in the Eye 4PillPack Raises $50 Million to Build Retail Footprint and Accelerate Growth 2PillPack Raises $50 Million to Build Retail Footprint and Accelerate Growth 3
... University Hospitals (UH) in Cleveland, OH, and ... venture to construct a comprehensive inpatient rehabilitation hospital ... completion in October 2012, the state-of-the-art facility will ... with specialized rehabilitation nursing and a wide range ...
... Echo Therapeutics, Inc. (Nasdaq: ECTE ), ... a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) system ... today announced results for the period ended June 30, ... through Echo,s website at www.echotx.com . ...
Cached Medicine Technology:University Hospitals and Centerre Healthcare Announce Joint Venture to Open Comprehensive Inpatient Rehabilitation Hospital 2Echo Therapeutics Announces Second Quarter 2011 Financial Results 2Echo Therapeutics Announces Second Quarter 2011 Financial Results 3Echo Therapeutics Announces Second Quarter 2011 Financial Results 4Echo Therapeutics Announces Second Quarter 2011 Financial Results 5Echo Therapeutics Announces Second Quarter 2011 Financial Results 6
(Date:6/3/2015)... 2015 On June 22, 2015, Medicare ... drug sensitivity (pharmacogenetic) testing that it has reimbursed since 2009. ... as 19 million of the 49 million Medicare beneficiaries in ... life-threatening adverse drug events.(1) Sadly, if it became a standard ... Medicine, the use of an individual’s genetic information to tailor ...
(Date:6/3/2015)... 03, 2015 Dr. Steven Reisman, a nationally ... Center ( http://www.newyorkcardiac.com ) located in NYC, announced today the ... his practice. In most cases, depending on the level of ... they call, they will be seen by a cardiologist that ... a cardiologist is to ensure that people who have an ...
(Date:6/3/2015)... Alberto Grignolo, PhD, will be honored with a ... Global Inspire Award program recognizes the organization’s outstanding volunteers ... service on a global scale. , Grignolo ... one DIA member for meritorious service through a leadership ... foster innovation to improve health and well-being worldwide. , ...
(Date:6/3/2015)... Justina Molzon, MS Pharm, JD will be honored ... Meeting. DIA’s Global Inspire Award program recognizes the organization’s ... commitment to service on a global scale. ... that recognizes the “Member of the Year” who consistently ... has contributed to the advancement of DIA’s mission. ...
(Date:6/3/2015)... (PRWEB) June 03, 2015 Visual ... Analytics solutions, today announced the launch of the ... (DSX) for SAP® BusinessObjects™ Design Studio. The Design ... visualization capabilities and advanced functionalities into their dashboarding ... DSX suite, Visual BI is adding key components ...
Breaking Medicine News(10 mins):Health News:Medicare Limiting Coverage Benefit for Drug Sensitivity Testing on June 22, 2015 2Health News:Medicare Limiting Coverage Benefit for Drug Sensitivity Testing on June 22, 2015 3Health News:Medicare Limiting Coverage Benefit for Drug Sensitivity Testing on June 22, 2015 4Health News:Medicare Limiting Coverage Benefit for Drug Sensitivity Testing on June 22, 2015 5Health News:Medicare Limiting Coverage Benefit for Drug Sensitivity Testing on June 22, 2015 6Health News:Medicare Limiting Coverage Benefit for Drug Sensitivity Testing on June 22, 2015 7Health News:NYC Cardiologist, Dr. Steven Reisman, Announces Same Day and Evening Appointments 2Health News:Longtime DIA Champion and PAREXEL Executive Honored with Global Inspire Award at DIA’s Annual Meeting 2Health News:Longtime DIA Champion and PAREXEL Executive Honored with Global Inspire Award at DIA’s Annual Meeting 3Health News:Former FDA Official and U.S. Public Health Service Officer to Be Honored with Global Inspire Award at DIA’s 2015 51st Annual Meeting 2Health News:Former FDA Official and U.S. Public Health Service Officer to Be Honored with Global Inspire Award at DIA’s 2015 51st Annual Meeting 3Health News:Visual BI Launches Second Release for its Design Studio EXtensions (DSX) for SAP® BusinessObjects™ Design Studio 2Health News:Visual BI Launches Second Release for its Design Studio EXtensions (DSX) for SAP® BusinessObjects™ Design Studio 3
... News) -- The pain of knee osteoarthritis is more severe ... pain, a new study has found. In the study, ... to 79, about pain in the lower back, neck, shoulder, ... back pain was significantly associated with higher knee pain scores. ...
... study released today estimates that the global initiative to ... US$40-50 billion if transmission of wild polioviruses is interrupted ... first rigorous evaluation of the benefits and costs of ... ever undertaken by the global health community. The study ...
... Oliver Daumke of the Max Delbrck Center for Molecular ... Excellence in Science Award 2010" in the biology category. ... his contributions to the understanding of the structure and ... Together with him, two other scientists, Professor Nicolai Cramer ...
... Nov. 20 (HealthDay News) -- Kidney failure patients who ... had significantly better heart function, overall health and general ... stems from an analysis that compared the impact of ... per week, for three to four hours per session ...
... News) -- If teens, desires for health care privacy ... study suggests. Teens are cautious about revealing sensitive ... judged, and are reluctant to talk to unfamiliar or ... Hospital Medical Center. The researchers conducted 12 focus ...
... financial crisis still hanging over many countries, this year,s ... Systems Financing: The Path to Universal Coverage" is timely ... that all people have access to health care services, ... a Perspective article on the 2010 World Health Report ...
Cached Medicine News:Health News:Economic benefits of the global polio eradication initiative estimated at $40-50 billion 2Health News:Doubling Frequency of Dialysis May Help Kidney Failure Patients 2Health News:Doubling Frequency of Dialysis May Help Kidney Failure Patients 3Health News:For Teens, Privacy May Trump Health Care 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: