Navigation Links
Newly Published Study Results Showed That Two Mealtime Insulin Dosing Algorithms Were Effective for Patients with Type 2 Diabetes
Date:7/22/2008

Two Regimens Including Lantus(R) and Apidra(R) Resulted in Significant Reductions in A1C in Patients with Type 2 Diabetes, Whatever the Algorithm

Used

BRIDGEWATER, N.J., July 22 /PRNewswire/ -- Results from the "Adjust to Target in Type 2 Diabetes: Comparison of a Simple Algorithm to Carbohydrate Counting for Adjustment of Mealtime Insulin Glulisine" study, were published in the American Diabetes Association's (ADA) medical journal, Diabetes Care. This study, using a basal-bolus insulin regimen with Lantus(R) (insulin glargine [rDNA origin] injection) once daily (basal insulin) and rapid-acting Apidra(R) (insulin glulisine [rDNA origin] injection) at mealtime (bolus insulin) demonstrated significant reductions in postprandial blood glucose and A1C using two different dosing algorithms.

The 24-week, multicenter, randomized, controlled study compared two algorithms for adjusting mealtime insulin (Apidra(R)) in 273 intent-to-treat patients with type 2 diabetes. Apidra(R) and Lantus(R) were adjusted weekly in both groups based on the previous week's self-monitored blood glucose (SMBG) results. One group, the "Simplified Algorithm" group, was provided set doses of Apidra(R) to take before each meal. The second group, the "Carbohydrate Counting" group, was provided an insulin-to-carbohydrate ratio to use for each meal and adjusted their Apidra(R) dose based on amount of carbohydrate consumed. After 24 weeks, the percentage of patients who achieved A1C<7 percent -- the ADA's recommended target for blood sugar control -- while following these two treatment algorithms were 73% and 69% (P=0.70), respectively.

Average A1C levels at week 24 were 6.70 in the Simplified Algorithm group and 6.54 percent in the Carb Counting group. The respective mean A1C changes from baseline to 24 weeks were -1.46 percent and -1.59 percent (P=.24). A1C <7.0 percent was achieved by 73 percent (Simplified Algorithm) and 69 percent (C
'/>"/>

SOURCE sanofi-aventis
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
2. Sixty-One Percent of Newly Diagnosed Parkinsons Disease Patients Do Not Receive Any Drug Treatment in the First Year of Diagnosis
3. Phase III Clinical Trial in Newly Diagnosed Multiple Myeloma Stopped Early Due to Highly Significant Efficacy Advantage of VELCADE(R) (Bortezomib) for Injection Based Therapy Across All Endpoints
4. Newly Published Phase II Study Shows the Investigational Drug Vandetanib Prolongs Progression-Free Survival in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
5. New Data to Support VELCADE(R) (Bortezomib) For Injection Based Therapies as Setting New Standards in The Care of Newly Diagnosed Patients With Multiple Myeloma
6. Newly Approved HIV Drug Shows Great Promise
7. New Data Support High Complete Remission Rates With VELCADE(R) (Bortezomib) for Injection Based Therapies in Patients With Newly Diagnosed Multiple Myeloma
8. VELCADE(R) (Bortezomib) for Injection Based Treatment Delivers Impressive Complete Response and Survival in Patients With Newly Diagnosed Multiple Myeloma
9. Multiple Clinical Trials of VELCADE(R) (Bortezomib) for Injection Based Therapies Demonstrate High Complete Remission Rates in Patients with Newly Diagnosed Multiple Myeloma
10. Newly Published Study Shows OPKOs siRNA Bevasiranib Is Taken Up by Target Tissues in the Eye
11. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... Research and Markets ( http://www.researchandmarkets.com/research/dl9gbg/admetoxicology ) ... - Global Strategic Business Report" report to their ... for ADME-Toxicology Testing in US$ Million by the following ... The report provides separate comprehensive analytics for ... Japan , Europe , ...
(Date:4/17/2015)... and DETROIT , April 17, 2015 ... live in poverty, the infant mortality rate is two and ... per 1,000 live births. Nearly 6 of 10 infants that ... adequate prenatal care.  These are sobering statistics that Covenant Community ... people of Metro Detroit, is poised to change thanks to ...
(Date:4/17/2015)...  Over the next five years, the marijuana industry in ... predicting that 14 more states will legalize recreational marijuana and ... for legal cannabis grew 74 percent in 2014 to $2.7 ... market could grow more than fourfold to $11 billion in ... on marijuana. Cannabiz Mobile Inc. (OTCBB: LGBI) is ...
Breaking Medicine Technology:ADME-Toxicology Testing (In-Vivo, & In-Vitro) Market - Global Strategic Business Report 2015: Pharma Industry Renews Focus on Cost Optimization 2Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 2Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 3Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 4Cannabiz Mobile Analyst Brief: Next Big Thing by Torus IR Issued by BrokerBank Securities, Inc. 2
(Date:4/18/2015)... (PRWEB) April 18, 2015 Thousand of ... on behalf of individuals who were allegedly harmed by ... to move forward in the U.S. District Court, Northern ... 10th, the Court has amended an earlier Case Management ... Among other things, the new amendment permits the claims ...
(Date:4/18/2015)... April 18, 2015 On April 14th, 2015, ... Report , which they say, “exposes a tactical shift by ... malware variants were introduced in 2014 - almost a million ... Day threats to be identified and patched by prominent manufacturers ... clear that doing business in a digital world can be ...
(Date:4/18/2015)... FL (PRWEB) April 18, 2015 PHOENIX, ... Hillsborough County, along with 11 other secure destruction professionals ... Secure Destruction Specialists (CSDS). He will now display “CSDS” ... exams were offered before the National Association of Information ... Illinois and another Grapevine, Texas. Of the 20 people ...
(Date:4/17/2015)... John Evans, a Gardant affordable assisted ... from 2 p.m. to 3 p.m. on April 24. ... Ct. in Pekin, Illinois, serves older adults of all ... to maintain their independence. , Becky Baker will entertain ... be served during the luau. , For more information, ...
(Date:4/17/2015)... Riviera Magazine has featured ... of the Gallery of Cosmetic Surgery in Newport Beach, ... The publication focused on his expertise in the ... grafting, eyelid surgery, laser resurfacing and rhinoplasty. , Dr. ... has resulted in thousands of satisfied patients across the ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 4Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 5Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 3
... 27 Retirees who are able to supplement their ... their whole life insura n ce ... on track during future recessions, according to planning scenarios studied by ... By drawing on the cash values of their whole life insurance ...
... among poor, report finds , THURSDAY, Aug. 27 (HealthDay News) ... recommended vaccinations, but greater efforts are needed to reach youngsters ... , A 2008 survey of children from 19 months to ... 2007, found that 76.1 percent had received the recommended series ...
... , , Nearly two-thirds of Americans are ... , WASHINGTON, Aug. 27 A recent poll on the H1N1 ... or planning on taking extra measures to cover their coughs and sneezes with ... flu. , , (Logo: http://www.newscom.com/cgi-bin/prnh/20090108/RedCrossLOGO ) , ...
... fields of science, technology and medicine, has signed an ... journal, Hormones & Cancer , starting in January ... deadly cancer subtypes, cancers of the breast and prostate. ... Cancer will include research articles covering other less-commonly ...
... , , , , ... practice for dentists to perform repeat root canals and other procedures ... loss. Today, the American Academy of Implant Dentistry (AAID) said ... save failing teeth and replace them with long-lasting dental implants. ...
... , ... to present latest research findings at ASHG 2009 Meeting in Honolulu, Hawaii -- October 20-24, ... ... human genetics field will gather in Honolulu, Hawaii to present their latest research findings at ...
Cached Medicine News:Health News:MassMutual Analysis: Whole Life Insurance Can Help Supply Retirement Income, Preserve Equity Portfolios During Bear Markets 2Health News:MassMutual Analysis: Whole Life Insurance Can Help Supply Retirement Income, Preserve Equity Portfolios During Bear Markets 3Health News:MassMutual Analysis: Whole Life Insurance Can Help Supply Retirement Income, Preserve Equity Portfolios During Bear Markets 4Health News:MassMutual Analysis: Whole Life Insurance Can Help Supply Retirement Income, Preserve Equity Portfolios During Bear Markets 5Health News:U.S. Childhood Vaccine Rates Good But Could Be Better: CDC 2Health News:Red Cross Survey Finds Overwhelming Majority of Public Taking Steps against H1N1 Flu Virus 2Health News:Red Cross Survey Finds Overwhelming Majority of Public Taking Steps against H1N1 Flu Virus 3Health News:Springer signs publishing agreement with the Endocrine Society 2Health News:Why Save Bad Teeth? Dental 'Heroics' Unnecessary and Failure Prone 2Health News:The American Society of Human Genetics Hosts 59th Annual Meeting 2Health News:The American Society of Human Genetics Hosts 59th Annual Meeting 3Health News:The American Society of Human Genetics Hosts 59th Annual Meeting 4Health News:The American Society of Human Genetics Hosts 59th Annual Meeting 5
... Ultra MD Super Pulse sealed CO2 ... versatility backed by the experience and support ... years of surgical laser experience. All settings ... finger. The Ultra MD Super Pulse surgical ...
The compact size and portability of the Epic system makes it a cost-effective solution for single or multi-office use....
A soft contact lens that lets presbyopes see clearly and comfortably at all distances , without the hassles of bifocals or reading glasses. Recommended for daily wear. Also approved for extended wear...
... display of corneal layers: endothelium, ... epithelial layers. Accurate analysis of ... keratocytes, nerve fibres, basal & ... surgery and pathology: optical pachymetry, ...
Medicine Products: