Navigation Links
NewLink Genetics Presents Preclinical Data on NLG919, a New Drug Candidate from a Novel Class of IDO Pathway Inhibitors for the Treatment of Cancer
Date:4/4/2013

AMES, Iowa, April 4, 2013 /PRNewswire/ -- NewLink Genetics Corporation (NASDAQ: NLNK) is a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics. The company today announced that preclinical data on one of its IDO pathway inhibitors, NLG919, will be presented at the 2013 Annual Meeting of the American Association for Cancer Research (AACR) to be held April 6-10 in Washington, DC. The poster presentation will describe the benefits of targeting the IDO pathway with small molecule immunomodulatory drugs for the treatment of cancer. NLG919 is in development as a potent IDO pathway inhibitor with desirable pharmacological properties.

Poster presentation:

  • (Poster #491): Sunday, April 7, 2013, 1:00 -5:00 PM, "NLG919, a novel indoleamine-2,3-dioxygenase (IDO)-pathway inhibitor drug candidate for cancer therapy," M. Mautino, Immunology 2: Vaccines, Immune Modulatory Agents, and Environment, Hall A-C, Poster Section 22, in The Washington Convention Center.

About inhibition of the IDO pathway

IDO pathway inhibitors are another class of immune check point inhibitors akin to the recently developed antibodies targeting CTLA-4 and PD-1 which represent a potential breakthrough approach to cancer therapy.  The IDO pathway regulates immune response by suppressing T-cell function and enabling local tumor immune escape. Recent studies have demonstrated that the IDO pathway is active in many cancers, both within tumor cells as a direct defense against T-cell attack, and also within antigen presenting cells in tumor draining lymph nodes whereby this pathway promotes peripheral tolerance to tumor associated antigens (TAAs).  When hijacked by developing cancers in this
'/>"/>

SOURCE NewLink Genetics Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. NewLink Genetics Announces Timing of Fourth Quarter and Year-End 2012 Financial Results Conference Call
2. NewLink Genetics Corporation Announces Exercise of Underwriters Option and Closing of Public Offering of Common Stock
3. NewLink Genetics Corporation Announces Pricing of Public Offering of Common Stock
4. NewLink Genetics Corporation Announces Proposed Public Offering of Common Stock
5. Clinical Data from NewLink Genetics HyperAcute Prostate Cancer Immunotherapy Published in Journal of Immunotherapy
6. Lota S. Zoth joins NewLinks Board of Directors; heads Audit Committee
7. Epigenetics Technology Market (Epigenomics, DNA Methylation, Histone Modifications, RNA Interference, Cancer Therapeutics, Personalized Medicine) (2012 - 2017)
8. Amgen to Acquire deCODE Genetics, a Global Leader in Human Genetics
9. Submit Questions to Nobel Laureates and Other Experts about Genetics and Society
10. The International Serious Adverse Event Consortium and UC San Diego To Collaborate On Research Into The Genetics Of Drug Induced Renal Injury
11. Millennium Laboratories Announces Landmark Pharmacogenetics Clinical Outcomes Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... plc (NYSE: MNK ) announced today that ... program. The open-ended authorization permits the company to repurchase ... "Funding additional initiatives and seeking attractive ... to pursue a range of focused growth strategies," said ...
(Date:1/22/2015)... CLEVELAND , Jan. 22, 2015  ViewRay™, a privately ... entered into an exclusive distributor agreement with ITOCHU Corporation ... radiation therapy system for the treatment of cancer in ... (me-rid-i-an) system, is the world,s first and only MRI-guided ...
(Date:1/22/2015)... 22, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" or ... Omega-3 therapies for cardiovascular disease and overall health is pleased ... in 2014 and its outlook for 2015 from the CEO, ... We would like to take this opportunity to ...
Breaking Medicine Technology:Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7
... 2011 The New Jersey Patient Care and Access Coalition ... encourages men and their families to speak out to preserve ... Force (USPSTF) recommended healthy men should no longer receive prostate-specific ... This decision was made by a panel ...
... 2011 Masimo (NASDAQ: ... Japanese Ministry of Health Labor & Welfare (MHLW) ... rainbow® Acoustic Monitoring technology—providing noninvasive and continuous acoustic ... and enhance patient compliance.  Available for the first ...
Cached Medicine Technology:NJ Docs Say Cancer Detection Tool Saves Lives 2Masimo rainbow Acoustic Monitoring Technology Cleared for Market in Japan 2Masimo rainbow Acoustic Monitoring Technology Cleared for Market in Japan 3Masimo rainbow Acoustic Monitoring Technology Cleared for Market in Japan 4Masimo rainbow Acoustic Monitoring Technology Cleared for Market in Japan 5Masimo rainbow Acoustic Monitoring Technology Cleared for Market in Japan 6
(Date:1/22/2015)... The U.S. Pharmacopeial Convention is pleased to announce ... Services at North Carolina State’s College of Veterinary Medicine ... Award for Distinguished Volunteer Service—the organization’s highest award. ... of volunteer experts to direct its work to improve ...
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the release of ... kids with cancer. The Chemo Duck App, available on iTunes for ... games to help children of all ages living with cancer adjust ... kids entertained, educated and at ease while waiting for clinic visits ...
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota (Blue ... means to “Live Fearless.” , The “Faces of ... stories about how they or someone they know has faced ... in the moment. By telling these types of stories through ...
(Date:1/22/2015)... 2015 Thousand of GranuFlo lawsuits ( ... its GranuFlo and NaturaLyte dialysis concentrates continue to move ... District Court, District of Massachusetts, Bernstein Liebhard LLP reports. ... has remanded a case filed by the state of ...
(Date:1/22/2015)... York, NY (PRWEB) January 22, 2015 ... College of Sports Medicine flagship journal Medicine & ... with L-Citrulline before exercise may help reduce gastrointestinal ... exercise. 1 , Participants in the double-blind, ...
Breaking Medicine News(10 mins):Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 2Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 3Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 4Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3
... Mean Unbeatable Consumer Value Queen c2 Mattress Starts at $699.99; One ... ... Minneapolis, MN (Vocus) February 26, 2009 -- In today,s uncertain economy, ... while they are buying fewer things, they are buying when they ...
... Dean Farms in New Castle, Lawrence County, has ... sales of raw milk on Feb. 26, Pennsylvania Agriculture ... that has not been pasteurized. Pennsylvania farms selling raw ... milk laboratory tested due to the health risks associated ...
... 26 The Communications Workers of America commended President ... administration,s proposed budget that will move our nation closer ... budget plan, the President has signaled his commitment to ... quality, affordable care. He understands the economic toll that ...
... hospitals tracked by HIMSS Analytics has achieved this recognition for implementation of ... ... As the country moves to transform healthcare with the passing of the ... 6 by HIMSS Analytics serve as role models in healthcare IT ...
... The Susan G. Komen for the Cure(R) Advocacy ... groundwork for fundamental health care reform and for ... to cancer with the release of his first ... Tuesday evening to hear President Obama voice his ...
... Predictive medicine company PreMD Inc. (TSX: PMD; PREMF.pk) today ... of the Corporation. Mr. Davis has been a director ... express my sincere thanks to Paul for his contribution ... PreMD.About PreMD Inc.PreMD Inc. has rapid, non-invasive tests for ...
Cached Medicine News:Health News:Select Comfort Launches Entirely Redesigned Line Of Sleep Number Beds 2Health News:Select Comfort Launches Entirely Redesigned Line Of Sleep Number Beds 3Health News:Select Comfort Launches Entirely Redesigned Line Of Sleep Number Beds 4Health News:Lawrence County Raw Milk Dairy Tests Negative For Campylobacter; Raw Milk Sales Resumed 2Health News:Honored for EMR Sophistication, HIMSS Analytics Announces Stage 6 Hospitals 2Health News:Honored for EMR Sophistication, HIMSS Analytics Announces Stage 6 Hospitals 3Health News:Susan G. Komen for the Cure(R) Advocacy Alliance Applauds Obama for Commitment to Health Reform, Cancer Research, in Budget Blueprint 2Health News:PreMD Announces Resignation of Director 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: