Navigation Links
New York Robotic Surgery Expert Dr. David Samadi, MD Discusses New Findings that Hormone Therapy May Increase Risk of Developing Colorectal Cancer

NEW YORK, Dec. 8, 2010 /PRNewswire/ -- Androgen deprivation therapy has often been prescribed as a prostate cancer treatment for low-risk prostate cancer patients. This therapy for treating prostate cancer had previously been blamed for increased risk of cardiovascular disease and heart conditions. However, this hormone treatment for prostate cancer has now become more controversial due to its two potential side effects, diabetes and obesity, which are risk factors for colorectal cancer. "Androgen deprivation therapy is overused, and now may be even more dangerous than previously thought," said Dr. Samadi, a robotic prostatectomy expert, as well as the Vice Chairman, Department of Urology, and Chief of Robotics and Minimally Invasive Surgery at The Mount Sinai Medical Center in New York City.


The University of Michigan study, which appears in the December issue of the Journal of the National Cancer Institute, found that androgen deprivation therapy, delivered via injections or surgical castration, resulted in a 30 to 40 percent increased risk for colorectal cancer. However, the absolute risk is small, with no more than a 2.5 percent absolute risk of colorectal cancer over a five-year period.

"When treating late-stage prostate cancer that has spread beyond the prostate gland, it's effective," said Dr. Samadi, "When coupled with radiation, it can be very beneficial in treating locally advanced prostate cancer." However, the study showed that as a primary therapy for lower-risk or localized prostate cancer tumors, there is no substantial evidence for androgen deprivation therapy.

Furthermore, analysts are still debating that the prostate cancer screening test, prostate-specific antigen (PSA), results in unneeded prostate cancer treatment, something Dr. Samadi does not believe. "The androgen deprivation therapy risk just further complicates the whole prostate cancer treatment issue," he said, "Androgen deprivation therapy patients are undergoing the procedure when there is an elevated PSA as a result of a biochemical tumor recurrence. So the benefit is not definitive," says Samadi.

Additionally, the length of time patients received the hormone therapy increased their risk of developing colorectal cancer. Men who had their testicles removed had the highest risk. "Obesity has always been a significant risk factor, especially for men, for a wide variety of diseases, including colorectal cancer," said Dr. Samadi, a da Vinci prostatectomy expert who is also skilled in open prostatectomy as well as laparoscopic prostatectomy, "Obese men have lowered androgen levels, which suggests a direct link to colorectal cancer development."

Critics of the study believe that men receive a prostate cancer diagnosis usually undergo colorectal cancer screening for the first time, so cancer is detected only because of screening and not the hormone treatment for prostate cancer. A study would have to be conducted to assess the incidence of colorectal screening in men who received hormone therapy, a radical prostatectomy or no treatment.

Dr. Samadi explained that random biopsies are not accurate enough to image the entire prostate. Therefore it's insufficient to provide doctors with enough information on staging. "Not many patients realize that there is usually a 40 percent upgrading of the disease after the prostate is removed, which is also a strong argument against radiation as the primary treatment for prostate cancer," he said.

"Hormones and radiation go hand in hand and with all of the inherent risks, which is why I prefer prostate removal surgery and providing a total cure for patients," said Dr. Samadi, "However, this study highlights the continued need for a routine colorectal cancer screening and better lifestyle habits, such as exercise, to help diseases such as colorectal cancer."CONTACT:Dr. David B. Samadi1-855-DrSamadi

Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Society of Gynecologic Oncologists 40th Annual Meeting on Womens Cancer to Include Sessions on Robotics Surgery
2. Cardiums InnerCool Announces Positive Benefits of Cooling During Robotic-Assisted Prostate Surgery Published in Urology
3. WORLDS First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center
4. Health Robotics CytoCare(TM) Global Expansion Continues With Grifols International in Latin America
5. Health Robotics Announces Official i.v.STATION(TM) Inauguration at Gregorio Maranon University Hospital
6. ATS Medical Announces First in World Human Robotic Endoscopic Aortic Valve Replacement
7. El Camino Hospital Expands Robotic Surgery Program
8. Milestone Achieved in Revolutionary Robotic Thyroid Surgery
9. Health Robotics Reaches 100% Asia-Pacific Coverage Through its New Exclusive Distribution Contract With BioRobotics in Korea
10. HDT Develops Robotic Arm Technology for DARPAs Revolutionizing Prosthetics 2009 Program
11. Health Robotics to Unveil TPNstation(TM) at the American Society of Health-System Pharmacists on December 7th
Post Your Comments:
(Date:9/28/2017)... Cohen Veterans Bioscience and Early Signal Foundation announce a ... sensors for real-time monitoring of patients with trauma-related and ... focused on disruptive health solutions for rare disorders and ... record and integrate behavioral, cognitive, physiological and contextual data. ... ...
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
(Date:9/18/2017)... , Sept. 18, 2017  PMD Healthcare of ... Pharmacy of Kalamazoo, Mich. , have ... service that expedites and streamlines patient and provider access ... 2.0, and wellness management services.  ... used to measure lung function for a variety of ...
Breaking Medicine Technology:
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
(Date:10/12/2017)... , ... October 12, 2017 , ... The American College ... to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in ... , In honor of Morris F. Collen, a pioneer in the field of medical ...
(Date:10/12/2017)... Malvern, PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best ... New York City on October 11, 2017. , The annual award competition recognizes editorial ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
Breaking Medicine News(10 mins):