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New White Paper from Tuberous Sclerosis Alliance Assesses Visual Field Risks of Vigabatrin
Date:12/5/2013

SILVER SPRING, Md., Dec. 6, 2013 /PRNewswire-USNewswire/ -- A new white paper from the Tuberous Sclerosis Alliance (TS Alliance), entitled "Vigabatrin-Associated Visual Field Loss (VAVFL): What You Need to Know," was released today at the American Epilepsy Society annual meeting in Washington, DC.  The white paper was written by Darcy A. Krueger, MD, PhD, Associate Professor, Clinical Pediatrics and Neurology, Tuberous Sclerosis Clinic, Cincinnati Children's Hospital. Vigabatrin is approved in the United States by the Food and Drug Administration to treat infantile spasms and medically refractory complex partial seizures that are common in tuberous sclerosis complex (TSC).

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"Infantile spasms occur in approximately one-third of children with TSC," says TS Alliance President and CEO Kari Luther Rosbeck. "Because vigabatrin is the first-line medication recommended in the recently released TSC Clinical Consensus Guidelines to treat these types of seizures, it was important to address the medication's side effects, which Dr. Krueger has done in this new white paper." 

"The purpose of this white paper is to provide an authoritative report about vigabatrin-associated visual field loss (VAVFL) based on published clinical reports and studies," Dr. Krueger explains. "This report was written for patients and their families and will help in making an informed decision about the use of vigabatrin to treat infantile spasms and/or complex partial epilepsy." The white paper summarizes and critically evaluates what is known about the prevalence of VAVFL following vigabatrin exposure and possible ways to manage any potential retinal toxicity as reported in published, peer-revie
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SOURCE Tuberous Sclerosis Alliance
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