HOUSTON, July 25, 2013 /PRNewswire/ -- Study* findings published online, ahead of print, in Cornea show that daily dietary supplementation with a unique combination of omega fatty acids (GLA, EPA and DHA) for six months is effective in improving ocular irritation symptoms and halting the progression of inflammation that characterizes moderate to severe dry eye.
The multicenter, double-blind, randomized, placebo-controlled clinical trial conducted at Baylor College of Medicine and Virginia Eye Consultants evaluated 38 post-menopausal women with tear dysfunction in both eyes. Participants randomly received a proprietary blend of omega fatty acids, antioxidants and other nutrients (HydroEye®), or a placebo every day. Patients were assessed at baseline, four-, 12- and 24-week intervals using a variety of disease parameters including Ocular Surface Disease Index (OSDI) symptom severity questionnaire, topographical indices (SAI and SRI), inflammatory biomarkers (HLA-DR and CD11c), Schirmer tear flow measurement, tear breakup time (TBUT), and conjunctival fluorescein and lissamine green staining. HydroEye was found to improve ocular irritation symptoms, suppress ocular surface inflammation, and maintain corneal surface smoothness. An irregular corneal surface contributes to both irritation and problematic visual symptoms.
"Prior to this study, clinical evidence showing that nutritional supplements were beneficial in treating dry eye was scarce. However, within three months, the group treated with HydroEye showed statistically significant improvements in irritation symptoms of dry eye, and no progression of ocular surface inflammation or corneal irregularity. The placebo group's dry eye symptoms actually worsened over the six-month testing period," said Ste
SOURCE ScienceBased Health
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