Navigation Links
New Study Shows Proprietary Canola Extract, Dermytol(TM), Produces Pronounced Decrease in Malignant Melanoma Tumor Volume
Date:4/7/2008

KGK Synergize Inc. Presents Findings Today

SAN DIEGO, April 7, 2008 /PRNewswire/ -- A new study presented at the Experimental Biology Annual Meeting shows that a proprietary blend extracted from canola, Dermytol(TM), produces a pronounced reduction of malignant melanoma cell growth. Dermytol(TM), a proprietary compound developed by KGK Synergize Inc., a biotechnology company in Ontario Canada, is designed to protect skin cells from damage that may lead to skin cancer.

Mal Evans, DVM, MSc, PhD, KGK Synergize Inc.'s Scientific Director, said, "Skin cancer rates have been rising, and we are likely to see that continue as the population ages. The National Cancer Institute (NCI) estimates that more than 62,000 Americans will be diagnosed with melanoma and one million Americans will be diagnosed with non-melanoma skin cancer this year. NCI expects more than 8,000 deaths from melanoma and less than 1,000 deaths from non-melanoma cancers this year.

"Dermytol(TM) has the potential to be used in anti-aging and sun-protection products to reduce damage to skin. Results of preclinical trials in animals have been promising leading to human trials now running in both Canada and the United States.

In the most recent study, male mice were fed either a Dermytol(TM)-canola oil mixture or just canola oil. In a separate part of the study, researchers applied either a Dermytol(TM) cream or a placebo cream onto the shaved skin of a different group of mice. After seven days of treatment, all of the mice were injected with malignant melanoma tumor cells. Dermytol(TM) or placebo treatments continued for 25 days.

The mice in both Dermytol(TM) groups benefited from their treatments. Compared to the controls, the orally treated mice showed an average decrease in tumor size by about 45 percent. The mice receiving the topical treatment benefited even more with a 61 percent decrease in tumor volume.

In this study and previous preclinical studies, Dermytol(TM) produced no adverse effects.

In a laboratory cell culture study, Dermytol(TM) inhibited the proliferation of human cancer cells.

In another study, dietary supplementation with Dermytol(TM) moderately delayed the onset of skin tumors and significantly reduced tumor growth rate in mice treated to induce non-melanoma skin cancers.

A trial involving 45 subjects with actinic keratoses -- precancerous skin lesions -- is underway. "The current treatment for actinic keratoses is removal by freezing which can be painful or the application of a cream that causes inflammation and blistering of the skin," said Evans. "We expect Dermytol(TM) to be a welcome option."

About KGK Synergize Inc:

KGK Synergize provides contract research services to the health nutrition, biotechnology and pharmaceutical industries which include analytical chemistry, in vitro assays, in vivo models, toxicology and human clinical trials.

In addition to its contract research capabilities, KGK has a Product Development Division, which brings new and innovative natural health products to the point where they are ready to be manufactured and marketed. These products include Sytrinol(TM) for cardiovascular health, Diabetinol(TM) for the treatment and/or prevention of Type II Diabetes, and Dermytol(TM), a new product for the protection of sun damage to the skin.


'/>"/>
SOURCE KGK Synergize Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. UltraShape(R) Non-Invasive Fat Reduction and Body Contouring Clinical Study Results Featured at American Society for Laser Medicine and Surgery Meeting
2. InterMune Provides Additional Information on ITMN-191 (R7227) MAD Study Results
3. EnVivo Pharmaceuticals Announces Initiation of Clinical Safety and Biomarker Study of Alpha-7 Nicotinic Agonist, EVP-6124, in Patients with Schizophrenia
4. Study Finds Taxus(R) Drug-Eluting Stent Beneficial in Treatment of Large Vessels
5. Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study
6. Gen-Probe Begins U.S. Clinical Study of Molecular Test for Human Papillomavirus, Which Causes Cervical Cancer
7. Ranolazine Shortens QT Interval and Improves Cardiac Relaxation in Study of Patients With Genetic Sodium Channel Disorder
8. Large Study Gives Nod to Drug-Eluting Stents in Heart Attack
9. Study Finds Repeated Episodes of Stent Thrombosis Common
10. Study Finds PCI Safe, Effective Despite Off-Site Cardiac Surgery
11. Study Results Show Investigational Drug, Prasugrel, Cuts Risk of Stent-Related Clots by More than Half Versus Clopidogrel
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... GERMANTOWN, Maryland , May 25, 2016 ... bedient dringenden Bedarf zur ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt ... und Entwicklungsvereinbarung mit Therawis Diagnostics GmbH zur Entwicklung ... zu sein. Ein erstes Projekt wird die Entwicklung ...
(Date:5/25/2016)... 2016  Zymo Research Corp. announced today the ... materials that help researchers obtain the most accurate ... The rapid growth of the study of microbiomes ... standard methods to improve the reproducibility and quality ... at every step of the measurement process including ...
(Date:5/25/2016)... YORK , May 25, 2016 ... Market Size, Share, Development, Growth and Demand Forecast to ... Syringe, Insulin Pump and Others)" published by P&S Market ... at $9,998.3 million in 2015, and it is expected ... Based on type, the insulin pump segment is expected ...
Breaking Medicine Technology:
(Date:5/31/2016)... ... 2016 , ... The Orthopaedic Research and Education Foundation (OREF) is pleased to ... MD, began his term as president in March, succeeding John J. Callaghan, MD, who ... president-elect. Richard F. Kyle, MD, will serve as chair, corporate development, succeeding Thomas P. ...
(Date:5/31/2016)... ... 31, 2016 , ... Phynd Technologies, Inc. announced recently the signing of three ... and Shore Medical Center – Somers Point, NJ. The new clients range in bed ... the breadth of Phynd’s solution and its interoperability. , Houston Methodist is a leading ...
(Date:5/31/2016)... ... 2016 , ... In a recent interview on The Greenburgh Report radio show ... WVOX (1460 AM), leading medical insurance advocate Adria Goldman Gross discussed several ... money maelstrom.” , During the interview with Mr. Feiner that aired on May ...
(Date:5/31/2016)... Scotch Plains, NJ (PRWEB) , ... May 31, 2016 , ... ... University of Medicine and Dentistry of New Jersey in the class of 1986, where ... family and cosmetic dentistry at his current location in Livingston since 1989. He has ...
(Date:5/31/2016)... ... May 31, 2016 , ... To meet ... to the healthcare industry, The University of Scranton is adding a Certificate in ... to a career in rapidly growing field of healthcare information. , Healthcare ...
Breaking Medicine News(10 mins):