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New Study Shows PCR and FCR Have Significant Activity in B-cell Chronic Lymphocytic Leukemia
Date:12/8/2008

patients."

The research found that both PCR and FCR have significant activity in CLL and can be given safely in the community setting. Both regimens possess significant toxicity and response rates in this multi-institution, community-based randomized trial were lower than previous Phase II trials of previously untreated patients. This trial did not demonstrate a lower infection rate with PCR using pentostatin at the 4 mg/m2 dose level. In early follow-up, no statistically significant differences with respect to overall response rate or survival were observed between FCR and PCR, although the CR rate was significantly higher with FCR.

This research will be presented at the 50th Annual Meeting of the American Society of Hematology on December 8, 2008 at 11:30 a.m. PST.

Physician researchers affiliated with the US Oncology network will also present the following US Oncology Research network studies as posters at this year's ASH conference:

  • Nicholas Di Bella, M.D., Rocky Mountain Cancer Centers-Parker: Results of a Phase II study of Bortezomib in patients with relapsed or refractory indolent lymphoma
  • Robert Rifkin, M.D., Rocky Mountain Cancer Centers-Midtown: Phase II open label-trial of Bortezomib in patients with multiple myeloma who have undergone high-dose melphalan therapy followed by autologous peripheral blood stem cell transplantation and failed to achieve a complete response.

The following physicians affiliated with the US Oncology network participated in the following studies that will be presented as oral and poster presentations and published studies at this year's ASH conference:

Acute Myeloid Leukemia (AML)

  • Roger Lyons, M.D., Cancer Care Centers of South Texas-Medical Center: Phase II study o
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SOURCE US Oncology
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