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New Study Reveals Collagenase SANTYL® Ointment More Effective Than Hydrogel Dressing for Pressure Ulcer Debridement
Date:9/30/2010

-term care setting where pressure ulcers continue to be a challenging issue requiring effective and convenient treatment solutions."

In difficult-to-heal and chronic wounds (such as diabetic, venous, and pressure ulcers) there is a continuous deposition of fibrotic and necrotic tissue that must be removed to maintain the readiness of the wound for healing. The process of removing these barriers to healing is called debridement.

Enzymatic debridement refers to the use of certain enzymes (types of proteins) to liquefy necrotic (dead) tissue, thus allowing bioburden to be more easily removed from the wound. More specifically, the collagenase enzyme liquefies the collagen fibers within necrotic tissue, the cellular and fibrotic debris (i.e., "bioburden") loosen their connections from each other and the wound bed, so they more easily wash away during routine cleansing at each dressing change.

Effective debridement to remove necrotic tissue, bacterial burden and the cellular debris of dead and abnormal cells is widely recognized as a critical first step in preparing a wound to heal. This consensus is supported by clinical studies that have shown that, in the presence of necrotic tissue, healing rates improve with increasing efficiency and frequency of debridement. There is also wide agreement that debridement should no longer be considered a one-time event; rather, effective ongoing or maintenance debridement until granulation tissue is well established should be provided to keep the wound microenvironment free of necrotic, bacterial and cellular barriers that can interfere with the wound's ability to progress toward healing.

"We are pleased to have provided support for this study as part of Healthpoint's ongoing commitment to research initiatives that contribute to the knowledge base of the clinical community," said Robert Bancroft, Executive Vice President, Strategic and Commercial Development of Healthpoint.  

The study was supp
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SOURCE HEALTHPOINT, Ltd.
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