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New Study Heralds Use of Blood Biomarkers to Predict Preeclampsia
Date:11/17/2009

clampsia is severe. They may also suffer catastrophic complications such as liver rupture.

The findings of this new study are published in the November issue of the Journal of Maternal-Fetal & Neonatal Medicine.

"Left untreated, preeclampsia leads to serious - or fatal - complications for both the mother and baby," says Dr Kusanovic of the Perinatology Research Branch of the NIH and Wayne State University/Hutzel Women's Hospital in Detroit, Michigan and lead author of the study.

"Our study found that maternal plasma concentrations (of angiogenic and antiangiogenic factors) together with a combination of other demographic, biochemical and biophysical factors are useful in assigning risk for the subsequent development of early-onset preeclampsia," explains Dr Roberto Romero, Chief of the Perinatology Research Branch of the NIH, who is one of the world's leading experts on this condition and in the study of complications of pregnancy.

"The establishment of an accurate means to assess the risk for preeclampsia will enable health care practitioners to identify women who require more intensive monitoring to safeguard both mother and baby from this devastating condition," says Dr Romero.

Dr Mario Merialdi, Coordinator for Improving Maternal and Perinatal Health at the World Health Organisation (WHO) said: "The results of the study conducted by the international team led by Dr Romero have important implications for clinical practice and public health policies. Hypertensive disorders of pregnancy are one of the major causes of maternal and fetal mortality worldwide."

"Reliable screening tests that could identify women at risk for developing preeclampsia are not yet available and the findings of Kusanovic et al. provide the scientific basis for the development of such tests," explained Dr Merialdi.

"The World Health Organization, in collaboration with
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SOURCE Journal of Maternal-Fetal & Neonatal Medicine
Copyright©2009 PR Newswire.
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