Navigation Links
New Research for Mechanical Support Devices in Pediatrics to Be Released at International Heart and Lung Transplant Meeting

BOSTON, April 9, 2008 /PRNewswire/ -- New devices and research for mechanical circulatory support in pediatrics from the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Pediatric Circulatory Support Program will be discussed at the International Society for Heart and Lung Transplantation (ISHLT) 28th Annual Meeting and Scientific Sessions. The meeting is ongoing this week at the Boston Marriott Copley Place and Hynes Convention Center.

The use of mechanical circulatory support devices (MCSDs) is shown to decrease wait list mortality and improve efficiency of organ utilization in children. Close to 1,800 children with congenital heart defects die each year, and 25 percent of the 36,000 babies born with these malformations require invasive treatment within the first year of life. Despite rapid technologic advances that have allowed development of sophisticated MCSDs for adults, very few such options exist for infants and children in need of mechanical circulatory support.

Acknowledging this vacancy, the NHLBI Pediatric Circulatory Support Program awarded five contracts to develop a family of devices. These include:
-- An implantable mixed-flow ventricular assist device designed

specifically for patients up to two years of age

-- Another mixed-flow ventricular assist device that can be implanted

intravascularly or extravascularly depending on size

-- Compact integrated pediatric cardiopulmonary assist systems

-- Apically implanted axial-flow ventricular assist device

-- Pulsatile-flow ventricular assist device.

"The field of pediatric mechanical circulatory support received a boost from the NHLBI program even beyond the much needed support for the development of these innovative new devices. There is a real sense of momentum in this field and the NHLBI program is largely responsible for this," said Brian Duncan, M.D., Pediatric and Congenital Heart Surgery, Children's Hospital, Cleveland Clinic.

At this year's meeting, Dr. Duncan will present data on the progress in development of each device. Because the program has reached its fifth year, the devices should soon be reaching the clinical trial phase, which Dr. Duncan will discuss as well.


The International Society for Heart and Lung Transplantation (ISHLT) is a not-for-profit organization dedicated to the advancement of the science and treatment of end-stage heart and lung diseases. Created in 1981, the society now includes more than 2,300 members from more than 45 countries, representing a variety of disciplines involved in the management and treatment of end-stage heart and lung disease.

ISHLT maintains two vital databases. The international Heart and Lung Transplant Registry is a one-of-a-kind registry that has been collecting data since 1983 from 223 hospitals from 18 countries. The ISHLT Mechanical Circulatory Device (MCSD) database has been collecting data since 2002 with the aim of identifying patient populations who may benefit from MCSD implantation; generating predictive models for outcomes; and assessing the mechanical and biological reliability of current and future devices. In Fall 2006 ISHLT released the first international guidelines for heart failure patient management. For more information, visit

Contact: Lauren Mason

(210) 857-2521

SOURCE International Society for Heart and Lung Transplantation
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Sunesis Pharmaceuticals to Present Non-Clinical Data at the Annual Meeting of the American Association for Cancer Research
2. SpineMark Partners With Regional Spine Leaders to Launch Its First Multisite Spine Research Organizations in Los Angeles, Denver
3. Alseres Pharmaceuticals, Inc. to Address a Congressional Briefing on Paralysis Research and the Spinal Cord Injury Community at Working 2 Walk in Washington, DC, April 13-15, 2008
4. Navigenics(TM) Genome Analysis Used In Research Trial on the Impact of Providing Genetic Risk Assessments
5. Recent siRNA Research Publications Support Silence Therapeutics Combined Development Approach
6. ACORNs Oncology-focused Contract Research Organization Exceeds Projections
7. Low Acid Coffee Backed By Scientific Research
8. Early Research Suggests Umbilical Cord Blood Cell Therapy May Reduce Progression of Alzheimers Disease
9. Stem Cell Research Provides Medical Breakthrough to Repair Heart Cell Damage Created by a Heart Attack
10. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Bioniche Life Sciences Inc.
11. Velos to Develop Key System Interface for Clinical Research
Post Your Comments:
(Date:11/24/2015)... FRANCISCO , Nov. 24, 2015  Thanks to ... Dignity Health St. Mary,s Medical Center,s Sister Diane Grassilli ... breast imaging capabilities in San Francisco ... an anonymous friend, stepped forward with a gift of ... for Breast Digital Mammography with Tomosynthesis and Whole Breast ...
(Date:11/24/2015)... Colo. , Nov. 24, 2015  Array ... that its Chief Executive Officer, Ron Squarer ... Healthcare Conference in New York.  The public is ... webcast on the Array BioPharma website.Event:Piper Jaffray Annual ... , Wednesday, December 2, 2015Time:1:30 p.m. Eastern Time ...
(Date:11/24/2015)... HOUSTON, TX and VANCOUVER, Nov. 24, 2015 /PRNewswire/ ... EPI; NASDAQ: EPIX ) announced today that the ... clinical study of EPI-506 as a treatment for metastatic ... States and Canada.  --> ... --> In the Phase 1/2 clinical trial, ...
Breaking Medicine Technology:
(Date:11/25/2015)... ... November 25, 2015 , ... “While riding the bus, I ... Bronx, N.Y. “I thought there had to be a convenient and comfortable way to ... The PROTECTOR enables disabled individuals to safely travel during cold or inclement weather. In ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible for advancing care ... disease. The Periwinkle Pioneers, nominated by the public, will receive special recognition throughout ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... philanthropic seniors, is resulting in a way for homeless people to have a ... have launched a new initiative whereby they are repurposing plastic bags into sleeping ...
(Date:11/25/2015)... ... November 25, 2015 , ... Since its launch in 2012, ... adult stem cell therapies to patients with chronic degenerative medical conditions. Now, the ... Registered Trademark (RTM). , Organizations are required to hold a registered trademark in ...
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software ... software creates an agreement between the practice owner and the patient that automatically ... notification, and projections. Click here to learn more. , ...
Breaking Medicine News(10 mins):