Navigation Links
New Research Suggests Platelet 'Stickiness' May be the Single Most Important Risk Factor in Patients Treated with Coronary Stents - Findings May be Applicable to Anyone with Vascular Disease
Date:1/27/2009

BALTIMORE, Jan. 27 /PRNewswire/ -- Most Americans know their cholesterol level, but do they know how "sticky" their platelets are? Research findings from Dr. Paul A. Gurbel, an interventional cardiologist and Director of the Sinai Center for Thrombosis Research based at Sinai Hospital of Baltimore, indicate that platelet aggregation or "stickiness" may be the single largest factor in determining the likelihood of developing serious complications, including heart attack, in patients treated with coronary artery stents.

"We currently measure the cholesterol level in everyone with vascular disease, yet the pivotal event that kills the patient - platelet aggregation isn't being assessed in any way," said Dr. Gurbel.

Dr. Gurbel's findings may explain why someone with no cardiac history could die suddenly of a massive heart attack, while an individual with high blood pressure, high cholesterol and plaque-filled arteries may never have a cardiac event because they had low platelet aggregation.

Along with his team at Sinai, Dr. Gurbel demonstrated that patients with platelets most prone to aggregate had the highest prevalence of complications, including heart attack, after coronary artery stenting.

Their work is helping to revolutionize the testing and treatment of patients with coronary artery disease, offering further evidence that a more personalized approach to anti-platelet therapy needs to be established.

Dr. Gurbel was one of the first researchers in the world to discover that up to 30% of patients taking clopidogrel, a drug designed to decrease platelet aggregation, do not respond to treatment.

"Of the millions of cardiac patients treated with clopidogrel, a significant percentage are non-responsive and remain at high risk for a major cardiac event," said Dr. Gurbel. "The platelet aggregation of each patient needs to be precisely measured to determine how well the drug is working. The blind administration of anti-platelet drugs without confirming a good response, in our opinion, will soon be reaching an end."

Click here for a recent story on Dr. Gurbel's research - http://www.wbaltv.com/video/17929792/index.html

About Sinai Hospital of Baltimore

Sinai Hospital of Baltimore is part of LifeBridge Health, a regional health organization that also includes Northwest Hospital, Levindale Hebrew Geriatric Center and Hospital, Jewish Convalescent & Nursing Home, and related subsidiaries and affiliates.


'/>"/>
SOURCE Sinai Hospital of Baltimore
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TVs 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol
2. Phidea Srl and Marvin Research Srl Announce Completion of Merger
3. Stents Can Treat - Not Just Prevent - Strokes, Suggests Early Research
4. Inclinix Releases Next Generation Critical Population Research(R) (CPR) for Clinical Trial Investigator Site Selection and Patient Recruitment
5. Beactica Announces Fragment-Based Drug Discovery Research Collaboration With GE Healthcare and Uppsala University
6. WaferGen and University of Texas Southwestern Medical Center Establish Biomarker Research Collaboration for SmartChip(TM) Real-Time PCR System
7. Michael J. Fox Foundation Awards $2.7 Million to Four Industry Teams for Pre-Clinical Parkinsons Disease Research
8. Fertility Physicians of Northern California Researchers Test New Forms of Progesterone Medication for Luteal Support During IVF
9. 2008 Human Research Protection Award Recipients Announced
10. New Research Reveals Unforeseen Side Effect of the Breast Cancer Movement
11. K-State Researcher Finds Correlation Between Childhood Obesity and Asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2017)... 18, 2017  EnteroMedics Inc. (NASDAQ: ... neuroblocking technology to treat obesity, metabolic diseases and ... an underwritten public offering of units for gross ... discounts and commissions and offering expenses payable by ... Class A Units, priced at a public offering ...
(Date:1/18/2017)... and PUNE, India , January 18, ... Allied Market Research, titled, "Breast Imaging Technologies Market by Type: ... global breast imaging technologies market size was valued at $2,544 ... by 2022, growing at a CAGR of 8.4% from 2016 ... Europe together accounted for over three-fourths market ...
(Date:1/18/2017)... , Jan. 18, 2017 The Philadelphia Pediatric ... companies developing medical devices for children. The Consortium ... receive seed grants of $50,000 each. The devices ... weak nerve signals, a hand-operated rapid blood delivery system for ... in babies. ...
Breaking Medicine Technology:
(Date:1/19/2017)... ... January 19, 2017 , ... Sam & Associates Insurance Agency, a ... residential clients in the California Bay Area, is launching a charity drive to raise ... , Heart disease is the primary killer of adult men and women in America, ...
(Date:1/19/2017)... ... , ... Attorney Robert “RC” Pate , founder of The Law Office ... Over Kid Cancer foundation. Each year, 175,000 children are diagnosed with pediatric cancers. In ... effect of the critical funding gap for research into pediatric cancer research. From 2006 ...
(Date:1/19/2017)... CT (PRWEB) , ... January 19, 2017 , ... Connecticut ... Sang H. Kim, a highly experienced and compassionate dermatologist. Dr. Kim brings an ... center . , “It is with considerable pleasure to welcome back Dr. Kim to ...
(Date:1/19/2017)... ... January 19, 2017 , ... Each year, the ... a conference where hundreds of surgeons from over fifteen different countries come together ... cosmetic breast augmentation to breast reconstruction for breast cancer patients, teaching ...
(Date:1/18/2017)... ... January 18, 2017 , ... From a health perspective, 2017 will clearly ... gut health to chronic disease, mental health and general physical well-being. The New York ... resolution to consider. , For one Charlottesville restaurant, good gut health is clearly on ...
Breaking Medicine News(10 mins):