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New Pre-Clinical and Clinical Data on GeNO LLC's Nitric Oxide Delivery Systems to Be Presented at 2013 American College of Cardiology and American Thoracic Society Medical Meetings
Date:1/29/2013

WALTHAM, Mass., Jan. 29, 2013 /PRNewswire/ -- GeNO LLC (www.genollc.com), a privately held pharmaceutical company developing a line of innovative nitric oxide drug products, today announced that new pre-clinical and clinical data from studies of GeNO's nitric oxide delivery systems will be presented at the American College of Cardiology's Annual Scientific Session in March 2013, and at the American Thoracic Society International Conference in May 2013.

GeNO's preclinical and clinical data will be included in the following presentations:

"Nitric Oxide Treatment of Right Ventricular (RV) Failure Associated with the Use of a Left Ventricular Assist Device (LVAD) and Hypoxemia-induced Pulmonary Hypertension" will be presented at the American College of Cardiology 62nd Annual Scientific Session in San Francisco, CA on March 11, 2013. The presentation will include pre-clinical data from a study showing GeNO's inhaled nitric oxide delivery system decreased pulmonary vascular resistance (PVR) and RV distension, increased RV ejection, and increased the maximum achievable LVAD speed and flow in a mammal model with LVAD associated RV failure and hypoxemia induced pulmonary hypertension.

"Ambulatory System for the Delivery of Nitric Oxide (NO) Derived from Liquid Dinitrogen Tetroxide (N2O4)" will be presented at the American Thoracic Society International Conference in Philadelphia, PA on May 20, 2013.  This pre-clinical data shows a novel approach for the delivery of inhaled nitric oxide to a mammal that, for the first time, uses a small volume of liquid rather than cylinders of compressed gas. The delivery system relies on evaporation of liquid N2O4 into NO2 gas, which is then reduced to ultrapure nitric oxide just prior to inhalation, using GeNO's proprieta
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