Navigation Links
New Post Hoc Analyses Examined the Effects of Neupro® (Rotigotine Transdermal System) on Daytime Functioning, Daytime Symptoms, Pain and Mood in Restless Legs Syndrome
Date:6/10/2011

BRUSSELS, June 10, 2011 /PRNewswire/ -- Results from new post hoc analyses assessing the effects of Neupro® (rotigotine transdermal system) in Restless Legs Syndrome (RLS) and utilizing novel surrogate markers suggested improved daytime functioning and daytime symptoms, reduced RLS-related pain and improved mood and depressive symptoms in patients with moderate to severe RLS. The data were presented at the 15th International Congress of Parkinson's disease and Movement disorders in Toronto, Canada.

Daytime functioning and daytime symptoms in RLS patients

RLS has been mainly associated with symptoms occurring in the late evening and at night. However, epidemiological studies and this post hoc analysis suggested that patients may also experience daytime symptoms and report impairment of daytime functioning.

Results of a post hoc analysis of a six month double blind study of rotigotine transdermal in 458 patients suggested improvement in daytime functioning and daytime symptoms in patients treated with rotigotine transdermal (1, 2 and 3 mg/24h, pooled data) than placebo.

"Daytime functioning symptoms, such as symptoms in the afternoon, sleepiness and tiredness due to bad sleep are a problem for many patients with moderate to severe RLS, and can adversely affect their ability to carry out everyday activities. While additional studies are needed, this post hoc analysis suggested that patients treated with rotigotine transdermal for 6 months may experience improvements in daytime functioning and daytime symptoms compared to those treated with placebo. These effects may be explained by the 24 hour coverage of symptoms, whenever they occur, with the application of transdermal rotigotine," said Dr. Ralf Kohnen, University of Erlangen-Nuremberg, Germany.

Significant improvements with rotigotine transdermal versus placebo (from baseline to end of maintenance) were seen in a series of measures of RLS symptom severity on the I
'/>"/>

SOURCE UCB
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Four Analyses of Three-Year Clinical Data Suggest CYPHER(R) Sirolimus-Eluting Coronary Stent May Provide Alternative to Surgery for Patients with Multivessel Disease
2. Xeloda XeNA Study Analyses of Xeloda, Docetaxel and Herceptin Combination Therapy for Metastatic Breast Cancer Featured at Major New Breast Cancer Symposium
3. Xeloda(R) XeNA Study Analyses of Xeloda, Docetaxel and Herceptin Combination Therapy for Metastatic Breast Cancer Featured at Major New Breast Cancer Symposium
4. Interim Response and Safety Analyses Support Continuation of Allos Therapeutics Pivotal Phase 2 PROPEL Trial of PDX in Patients with Peripheral T-Cell Lymphoma
5. New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG
6. New MIRCERA(R) Data Analyses to be Featured at the American Society of Nephrology Annual Meeting
7. New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer
8. Preliminary Analyses from Phase 2 Genzyme Study Highlight Efficacy and Safety of Clofarabine in Older Adult AML Patients
9. Independent Analyses of the SEAS, SHARP and IMPROVE-IT Studies of Ezetimibe
10. New Analyses Indicate that Divigel(R) (estradiol gel) 0.1% Is a Valuable Option for Certain Postmenopausal Women With Hot Flashes
11. Results and Additional Analyses From Efficacy and Safety Study of Cortheras Relaxin in Acute Heart Failure to be Presented at Heart Failure Congress 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... 29, 2014 /PRNewswire-iReach/ -- MHG Medical Management Services, ... its Medical Equipment and X-ray Annual Inspection ... tailored to the cruise industry,s unique requirements.  MHG ... to propose that they should develop a new ... is intended to create standardized processes and raise ...
(Date:7/29/2014)...  Roche (SIX: RO, ROG; OTCQX: RHHBY) launched its ... 2014 Clinical Lab Expo today by unveiling two booths ... is partnering with customers to redefine the value of ... day that they,re looking for a partner to help ... and offices," said Jack Phillips , president and ...
(Date:7/29/2014)... 2014  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ... second quarter 2014 financial results after the Nasdaq market ... host a live conference call and webcast to discuss ... morning, August 7, 2014 at 8:00 a.m. Eastern Time ... the live conference call by dialing 866-952-1907 (US) or ...
Breaking Medicine Technology:MHG Medical Management Services Aims to Change Cruise Industry Standard With New Equipment Maintenance Program 2Roche focuses on partnering with customers to redefine the value of the laboratory at the AACC 2014 Clinical Lab Expo 2Roche focuses on partnering with customers to redefine the value of the laboratory at the AACC 2014 Clinical Lab Expo 3Roche focuses on partnering with customers to redefine the value of the laboratory at the AACC 2014 Clinical Lab Expo 4Neurocrine Biosciences Announces Conference Call And Webcast To Report Second Quarter 2014 Financial Results 2
(Date:7/29/2014)... St. Petersburg, FL (PRWEB) July 30, 2014 Phytceramides ... explains how and why in her new book. , Today is ... Phytoceramides: Anti Aging At Its Best . The book is ... larger skin care book, but felt that Phytoceramides were ... sense to bring out this focused book now," says Kathy Heshelow, ...
(Date:7/29/2014)... Daily Gossip indicates that the new method ... symptoms that hemorrhoids commonly causes. The new method was ... expert. , The author of H Miracle reveals ... symptoms such as itching, burning, pain and swelling, as ... H Miracle by visiting the official website at: ...
(Date:7/29/2014)... 29, 2014 Daily Gossip reveals in its ... program claims that he cured his condition with the use ... share part of his experience. , He claimed that ... naturally in just 4 days. Since his method turned out ... from all around the world. , The Nasal Polyps ...
(Date:7/29/2014)... 29, 2014 DailyGossip.org reveals in its ... is a new method of naturally overcoming sciatica, in ... the new method ensure sufferers that the cure is ... , The new method is described as very ... sciatica with an 8 minutes per day treatment plan. ...
(Date:7/29/2014)... DailyGossip.org reveals in its latest review that ... can perfectly understand patients and what they have to go ... is the author of the new program. Ellie claims that ... suffering, Ellie started her very own research. Four years passed ... author of the Get Rid of Cold Sores program claims ...
Breaking Medicine News(10 mins):Health News:Last Day New Book Is Available at No Cost: Phytoceramides, Anti Aging At Its Best by Sublime Beauty Founder® Kathy Heshelow 2Health News:Last Day New Book Is Available at No Cost: Phytoceramides, Anti Aging At Its Best by Sublime Beauty Founder® Kathy Heshelow 3Health News:H Miracle Review Exposes Natural Method to Cure Hemorrhoids 2Health News:Nasal Polyps Treatment Miracle Review Reveals How to Cure Nasal Polyps Without Surgery 2Health News:Stop Sciatica in 8 Minutes Review Reveals the Way to Cure Sciatica Easily 2Health News:Get Rid of Cold Sores Fast Review Exposes the Way to Stop Outbreaks 2
... apnea, a dangerous medical condition that becomes more prevalent as ... deadly if left// untreated, says an expert. ,The ... irritation, with people being unaware that they are causing more ... the online edition of health portal News Medical. ...
... 'An ounce of prevention is worth a pound of cure.' , ... disease that could wipe the smile// off many faces and cause ... 43% of all cancers are preventable. Sunday, 4 February 2007, is ... will focus on strategies for a cancer free world – a ...
... College of Medicine finds that naltrexone may be beneficial to ... is often used to bring// relief to victims of alcohol ... inflammatory disorder of the intestine that affects an estimated 500,000 ... an early edition of the American Journal of Gastroenterology. ...
... hair dye are increasing as more and younger people dye ... dermatitis on the face and, in severe cases, facial swelling ... dyes currently contain para-phenylenediamine (PPD) and other related agents. During ... serious problem that it was banned from hair dyes in ...
... A promising step forward in the field of AIDS was ... to this 2-5AN6B, a nucleic acid, could actually stop the// ... ,This work was led by Robert J.Suhadolnik, Professor of ... 2-5AN6B in combination with drugs currently used for AIDS treatment ...
... menstrual cycles affect the responsiveness of their brains’ reward ... Mental Health (NIMH), a component of the National Institutes ... women were winning rewards, their circuitry was more active ... and dominated by estrogen, compared to a phase when ...
Cached Medicine News:Health News:'Cancer Prevention' - In Your Hands 2Health News:'Cancer Prevention' - In Your Hands 3Health News:NIMH Studies Woman’s Hormonal Cycl 2
Open blade design with aspiration capabilities for removing fluids from the operative site. 19 gauge wire....
Speculum can be used for any type of eye surgery. Arms of speculum lie flat due to joint between blade and arms. Features quick locking mechanism....
Pediatric model. Spring-controlled spread of blades with locking mechanism. Dull finish. Blades: 11 mm....
Fenestrated blades with screw-controlled spread. Dull finish. Blades: 16 mm....
Medicine Products: