Navigation Links
New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis
Date:9/19/2007

en infrequent reports of severe and occasionally incapacitating bone, joint and/or muscle pain. Rare occurrences of osteonecrosis, primarily of the jaw (ONJ), have been reported in patients receiving bisphosphonates. Most ONJ cases have occurred in cancer patients undergoing dental procedures. In the majority of cases reported, patients had received intravenous bisphosphonate therapy.

In clinical trials of up to 3-years duration, the overall incidence of adverse events with Actonel 5 mg daily was comparable to placebo. The most commonly reported adverse events regardless of causality were infection (primarily upper respiratory, placebo 29.7% vs Actonel 5 mg 29.9%), back pain (23.6% vs 26.1%), and arthralgia (21.1% vs 23.7%).

In a clinical trial comparing Actonel 35 mg Once-a-Week and Actonel 5 mg daily for 1 year, the overall safety and tolerability profiles of the two dosing regimens were similar. The most commonly reported adverse events regardless of causality were infection (Actonel 35 mg 20.6% vs Actonel 5 mg 19.0%), arthralgia (14.2% vs 11.5%) and constipation (12.2% vs 12.5%).

In a clinical trial comparing Actonel 75 mg two consecutive days/month and Actonel 5 mg daily for 1 year, the overall safety and tolerability profiles of the two dosing regimens were similar. The most commonly reported adverse events regardless of causality were arthralgia (Actonel 75 mg 10.4% vs Actonel 5 mg 9.5%), dyspepsia (9.1% vs 7.3%), and back pain (8.8% vs 10.8%).

Please see full prescribing information for Actonel(R) (risedronate sodium tablets) for additional safety information. For a copy of the full prescribing information for Actonel visit the Actonel Web site at http://www.actonel.com.

About The Alliance for Better Bone Health

The Alliance for Better Bone Health was formed in May 1997 to promote bone health and disease awareness through numerous activities to support physicians and patie
'/>"/>

SOURCE The Alliance for Better Bone Health
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
3. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
4. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
6. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
7. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
8. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
9. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
10. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
11. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... -- The fairness of the proposed acquisition of Thoratec Corporation ... Jude") is the subject of an investigation by WeissLaw ...  The investigation is focusing on possible breaches of fiduciary ... of Directors of THOR for agreeing to sell the ... announced it had reached a definitive agreement for St. ...
(Date:7/27/2015)... , July 20, 2015 ... has announced the addition of the "Cardiometabolic ... Afrezza,s discounted pricing is in line ... is critical to the product,s commercial appeal. However, ... prevent Afrezza from gaining a sizeable share of ...
(Date:7/27/2015)...  Attorney Advertising-- Bronstein, Gewirtz & Grossman, LLC is ... the securities of AMAG Pharmaceuticals Inc. ("AMAG" or ... advised to contact Peretz Bronstein or ... at info@bgandg.com or 212-697-6484. ... its officers and/or directors have violated Sections 10(b) ...
Breaking Medicine Technology:WeissLaw LLP: Thoratec Corporation Acquisition By St. Jude Medical May Not Be In The Best Interest Of THOR Shareholders 2Cardiometabolic Drug News Issue - Afrezza Aggressive Pricing Strategy View Playing Out 2Cardiometabolic Drug News Issue - Afrezza Aggressive Pricing Strategy View Playing Out 3SHAREHOLDER ALERT: Bronstein, Gewirtz & Grossman, LLC Announces Investigation of AMAG Pharmaceuticals Inc. 2
... PRINCETON, N.J. , June 21 Celator Pharmaceuticals today ... (Nasdaq: CEPH). The research agreement provides for the utilization of Celator,s ... at Cephalon. , , ... "We are pleased that work with this research program has ...
... June 21 U.S. District Court Judge Sidney A. Fitzwater ... class action lawsuit that left hundreds of premature babies with life threatening medical ... Canada will receive compensation under the settlement. , ... "It took years of litigation and research to pry relevant information ...
Cached Medicine Technology:Celator® Pharmaceuticals Expands Research Agreement With Cephalon, Inc. 2Celator® Pharmaceuticals Expands Research Agreement With Cephalon, Inc. 3Fort Worth Attorney Dwain Dent Comments on Final Judgment in Case That Left Hundreds of Babies Dead or Injured 2
(Date:7/27/2015)... ... July 27, 2015 , ... According to an article published by the ... has increased in Tennessee stemming from intravenous drug use. Intravenous drug use causes more ... for contracting communicable diseases including Hepatitis B and C and HIV. Drug treatment facilities ...
(Date:7/27/2015)... , ... July 27, 2015 , ... ... , providing a new way to understand and share your geospatial experience. These ... creatively designed maps to solve distinct business problems. , “Our world is more ...
(Date:7/27/2015)... ... July 27, 2015 , ... Dentist in Los Angeles , Dr. Poneh Ghasri, is ... of new beginnings for many people. Teeth whitening can help brighten up a person’s look, ... whitening is the safest and most effective way to get a whiter smile. Dr. Ghasri, ...
(Date:7/27/2015)... ... 2015 , ... Sher Fertility Institute, a national network of fertility ... physician to their clinical team in Las Vegas. , Dr. Mark Severino ... successful Reproductive Endocrinology teams in the region. , Combined Drs. Sher and Severino have ...
(Date:7/27/2015)... ... July 27, 2015 , ... The Advocator Group, LLC, a ... Jon Cogswell as the vice president of client services. Mr. Cogswell has over ... significant role in the growth and transformation of several businesses, including Bob’s Discount ...
Breaking Medicine News(10 mins):Health News:Tennessee Sees an Increase in Hepatitis C Infections from Intravenous Heroin Use 2Health News:Tennessee Sees an Increase in Hepatitis C Infections from Intravenous Heroin Use 3Health News:Hexagon Geospatial Visualizes Stories with the Hexagon Smart M.App® 2Health News:Hexagon Geospatial Visualizes Stories with the Hexagon Smart M.App® 3Health News:Los Angeles Cosmetic Dentist, Dr. Poneh Ghasri, Is Now Offering a Teeth Whitening Special Just in Time for Summer 2Health News:Dr. Mark Severino Joins Dr. Geoffrey Sher at Sher Fertility Las Vegas- Sher Fertility is National Network of Fertility Clinics Known for Exceptional Patient Care 2Health News:Dr. Mark Severino Joins Dr. Geoffrey Sher at Sher Fertility Las Vegas- Sher Fertility is National Network of Fertility Clinics Known for Exceptional Patient Care 3Health News:The Advocator Group, LLC Announces Jonathan Cogswell as Vice President of Client Services 2Health News:The Advocator Group, LLC Announces Jonathan Cogswell as Vice President of Client Services 3
... come up with a novel idea to boost up the sales of ... has announced a handsome reward of Rs. 100,000 for those who prove ... case has been registered in the state. And despite this, the bird ... Rs.100,000 if anyone proves bird flu case in the state," Rajesh Kumar ...
... the steel town were affected by a mysterious viral fever. ... a slum// cluster in Panposh on the outskirts of Rourkela, famous ... to other parts of the town. ,The high fever ... senior district health official. ,Most of the patients have ...
... days and devouring every bit of the Flu news, ... Own Country// , as recent as yesterday, has demonstrated a ... Flu or no flu. The Kerala Chicken Merchants’ Association threw ... hotel in Malappuram, Kerala. The party was open for all, ...
... Health officials have now urged cat owners to keep pets indoors. ... Ruegen. Initially it is in this region that more than 100 ... head of Germany's Friedrich Loeffler Institute said that the cat could ... disease was also detected among the wild cats in Asia. But ...
... After the cooling down of the bird flu scare, the ... diet of the non-veggies and has decided to bring back ... withdrawn the order prohibiting the serving of chickens and eggs ... catering units," the Railway ministry said in a statement. "It ...
... goods including small cars, anti-AIDS drugs, anti-cancer drugs would ... is one of the highlights of the annual budget ... ,The beneficiaries of this reduction will be the 800, ... the Tata Indica. The prices of 10 anti-AIDS drugs ...
Cached Medicine News:Health News:Bird Flu attacks the feline community 2
The Nervous System Flash Cards product uses the time tested content and images from BryanEdwards.com and displays the necessary images to demonstrate the nervous system....
... Cochrane Reviews enable all those involved ... date with the very latest evidence in ... which becomes harder each year as the ... this problem by delivering the best single ...
... Cochrane Reviews enable all those involved ... date with the very latest evidence in ... which becomes harder each year as the ... this problem by delivering the best single ...
Pocket Medicine's Cardiology Bundle includes the following 4 applications: Treatment Strategies in Cardiovascular Medicine, Treatment Strategies in Interventional Cardiology, Treatment Strategies in ...
Medicine Products: