Navigation Links
New Patent Awarded for Antigen-Sparing Vaccines that Elicit Robust Immunity
Date:1/30/2008

ANN ARBOR, Mich., Jan. 30 /PRNewswire/ -- A needle-free vaccine platform that elicits a robust immune response against a wide array of viruses and bacteria has been awarded a U.S. patent. The University of Michigan holds the patent and NanoBio Corporation, a spin-off from the university, licenses the patent and its associated technology.

The intranasal vaccines, produced using NanoBio's nanoemulsion technology, have elicited a dramatic immune response in animals vaccinated against influenza, anthrax, hepatitis B and other diseases. In some cases, the immune response is exponentially higher than what is required to provide adequate protection against infection. Such dramatic levels of immunity would confer significantly higher levels of protection to the vaccinated population at large compared with current injectable vaccines.

Because the vaccines trigger such robust immunity, scientists anticipate they will be able to reduce vaccine antigen quantities to a fraction of what current vaccines require, while still mounting an overwhelming immune response.

This "antigen-sparing" capability would enable scientists to rapidly produce large quantities of vaccines using miniscule amounts of antigen, a critical factor when faced with a disease pandemic or biological warfare.

"We've shown that when we mix our nanoemulsion with whole virus or a recombinant protein antigen and apply it to the naso-pharynx, the resulting vaccine elicits strong mucosal and systemic immunity," said James R. Baker Jr., M.D., founder and Chairman of NanoBio Corporation. "The nanoemulsion serves as an adjuvant to boost immune response against a specific antigen."

NanoBio is in various stages of testing its extensive pipeline of mucosal vaccines for influenza, bird flu, hepatitis B, HIV, RSV, small pox, anthrax and other viral and bacterial infections. Final results from the influenza vaccine study in ferrets are expected this quarter, and human tests with the
'/>"/>

SOURCE NanoBio Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. U.S. Patent Office Rejects Key HIV/AIDS Drug Patents at PUBPAT Request: Government Finds Prior Art Submitted By PUBPAT Invalidates All of Gilead Sciences Claims
2. Kibow Biotech Obtains Australian, Chinese and Indian Patents Protecting the Composition and Basic Technology Behind Its Oral Probiotic Formulation for Chronic Kidney Failure
3. DiObex, Inc. Awarded Patent for the Prevention of Insulin-Induced Hypoglycemia
4. Xenomics Announces Issuance of a US Patent That Covers Use of Transrenal Nucleic Acid Technology for Infectious Disease Diagnostics and Monitoring
5. Consumer Advocates Support Patent Office on Stem Cell Patent Rejection
6. AngioGenex Files Patent on First Small Molecule Id-Inhibitors for the Treatment of Cancer
7. Spectranetics Enrolls First Patient in PATENT Trial for the Treatment of Instent Restenosis
8. FAU Receives Patent for Invention Which Induces and Restores Cardiac Muscle Function
9. ArtJen Announces Major Clinical Trial of Its Patented Weight Loss Product FBCx
10. Quark Pharmaceuticals Files Patent Application Covering Novel Chemical Modifications to its RNAi Molecules
11. Fundamental Applied Biology, Inc. Is Awarded SBIR Phase IIB Grant for the Commercialization of Protein Therapeutics Using Cell Free Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... -- Sinovac Biotech Ltd. (NASDAQ: SVA ), ... China , announced that Sinovac Beijing, ... the Certificate of Good Manufacturing Practices for Pharmaceutical ... Food Administration (CFDA) for its proprietary vaccines, its ... filing and packaging facility. The GMP certificate covers ...
(Date:5/23/2013)... y PARÍS, 24 de mayo de 2013 ... un destacado desarrollador y fabricante de herramientas de ... diagnosis y tratamiento de la enfermedad vascular periférica ... ensayo ADVISE ( Ad enosine V asodilator ... valuation) II durante la sesión de ensayo clínico ...
(Date:5/23/2013)... 23, 2013 Hearing health affects a man,s lifestyle, ... remain socially and professionally engaged, he should address any hearing ... that the Better Hearing Institute (BHI) is delivering ... Men,s Health Week , which leads up to and includes ... June 10 through June 16. To help ...
Breaking Medicine Technology:Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 2Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4
(Date:5/24/2013)... New York, New York (PRWEB) May 24, 2013 ... da Vinci lawsuit involving Intuitive Surgical Inc.’s da ... According to court records, a Washington State Court ... not committed negligence in training a surgeon who performed ... several years later. The patient’s family had alleged ...
(Date:5/24/2013)... 24, 2013 Dwell Media LLC ... Huff as Executive Vice President of Digital for Dwell ... which represented a large portion of Yahoo's global media ... Dwell develops a fully-integrated commerce unit to launch in ... monetizing digital content for leading firms in Silicon Valley. ...
(Date:5/24/2013)... with high levels of cadmium in their urine are ... those with lower levels, a new study finds. ... of long-term exposure to the heavy metal that is ... Hopkins researchers explained. They also said their findings ... but instead suggest an association that requires further investigation. ...
(Date:5/24/2013)... According to the National Institutes of Health, Stevens Johnson Syndrome ... affects the skin and mucous membranes. SJS occurs most ... 30 (i). In the early stages SJS presents flu-like ... advances, it affects the mucous membranes such as the eyes, ... the eye causes conjunctivitis (pink eye). Inflammation of the ...
(Date:5/24/2013)... May 24, 2013 American Career College ... community, proudly participated in festivities surrounding the 2013 Toyota ... event provided the perfect backdrop to introduce the community ... E. 3rd Street, housed in an architectural gem known ... ACC was an active exhibitor throughout the weekend festivities. ...
Breaking Medicine News(10 mins):Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on Verdict in Nation’s First Trial Involving Alleged Da Vinci Complications 2Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on Verdict in Nation’s First Trial Involving Alleged Da Vinci Complications 3Health News:Yahoo Commerce Head Joins Leadership at Dwell Media 2Health News:High Cadmium Levels May Raise Risk for Dying From Liver Disease: Study 2Health News:Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines 2Health News:Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines 3Health News:American Career College Revs Up Community Support During Toyota Grand Prix of Long Beach 2
... -- Readmission rates have increased in many hospitals across ... elite academic medical centers, new research shows. About one ... within 30 days of being discharged for a medical ... for penalties -- reduced payments for readmissions -- for ...
... exposure to stressors in the Neonatal Intensive Care Unit ... and function of very preterm infants. According to the ... a journal published by Wiley-Blackwell on behalf of the ... experienced early exposure to stress displayed decreased brain size, ...
... , MONDAY, Oct. 3 (HealthDay News) -- The rate of ... rose dramatically over two decades, according to new government research. ... become the leading form of HPV-linked cancers, the researchers noted. ... percent of oral cancer samples tested positive for HPV. By ...
... Reporter , MONDAY, Oct. 3 (HealthDay News) -- Babies born very ... -- are five times more likely than full-term newborns to have ... study, based on Swedish medical databases, also found that being born ... seizure disorder as adults. Babies born as late as 35 to ...
... the strength of its synapses -- the connections between neurons ... a discovery that challenges conventional wisdom on the brain mechanisms ... brain "rhythm," or frequency, for changing synaptic strength. And further, ... to a different optimal frequency for learning. ...
... HealthDay Reporter , MONDAY, Oct. 3 (HealthDay News) ... recommended vaccination guidelines for their children, opting instead for ... delaying shots. And parents who do follow official ... schedule, according to new research. The findings alarm ...
Cached Medicine News:Health News:Hospital Readmission Rates on the Rise in Older Adults: Study 2Health News:Hospital Readmission Rates on the Rise in Older Adults: Study 3Health News:Preterm infants exposed to stressors in NICU display reduced brain size 2Health News:HPV-Linked Oral Cancers on the Rise, Study Finds 2Health News:HPV-Linked Oral Cancers on the Rise, Study Finds 3Health News:Preemies May Be at Higher Risk of Epilepsy Later in Life 2Health News:Preemies May Be at Higher Risk of Epilepsy Later in Life 3Health News:How the brain makes memories: Rhythmically! 2Health News:How the brain makes memories: Rhythmically! 3Health News:Some U.S. Parents Ignoring Vaccination Guidelines 2Health News:Some U.S. Parents Ignoring Vaccination Guidelines 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: